Date published: 2025-11-1

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TR β Activators

Santa Cruz Biotechnology now offers a broad range of TR β Activators for use in various applications. These compounds are essential tools in the study of transcriptional regulation, specifically in relation to the thyroid hormone receptor beta (TR β). TR β activators are crucial for exploring the mechanisms by which thyroid hormones influence gene expression, metabolism, and development. In scientific research, these activators are used to modulate the activity of TR β, allowing researchers to investigate the receptor's role in various physiological processes and its impact on cellular functions. This chemical category has been widely utilized in molecular biology and biochemistry to study the pathways and networks involved in thyroid hormone signaling. By using TR β activators, scientists can dissect the specific actions of TR β and differentiate them from other thyroid hormone receptors, providing a clearer understanding of the receptor's distinct functions. Moreover, these activators are valuable in developing assays and experimental models to study endocrine regulation and nuclear receptor biology. The availability of high-quality TR β activators facilitates advanced research in these fields, supporting the discovery of new insights into gene regulation and receptor biology. View detailed information on our available TR β Activators by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

3,3′,5-Triiodo-L-thyronine sodium salt

55-06-1sc-231968
sc-231968A
sc-231968B
100 mg
500 mg
1 g
$88.00
$240.00
$430.00
(0)

3,3',5-Triiodo-L-thyronine sodium salt demonstrates a remarkable ability to engage with thyroid hormone receptors, particularly favoring the TR beta isoform. Its triiodinated configuration contributes to enhanced stability and specificity in receptor binding, leading to distinct modulation of signaling pathways. The compound's unique physicochemical properties facilitate its diffusion across cellular membranes, while its dynamic conformational changes enable precise interactions with transcriptional machinery, influencing metabolic regulation.

GSK 4716

101574-65-6sc-203986
sc-203986A
10 mg
50 mg
$71.00
$285.00
(1)

GSK-4716 is a selective TRβ modulator, showing efficacy in altering lipid profiles and potentially beneficial in treating dyslipidemia and obesity.