Date published: 2025-9-13

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Thiol-Reactive

Santa Cruz Biotechnology now offers a broad range of Thiol-reactive compounds for use in various applications. Thiol-reactive chemicals are critical tools in biochemistry and molecular biology, primarily used for selectively modifying cysteine residues in proteins and peptides. This capability is essential for studying protein structure, function, and dynamics. These compounds enable researchers to tag proteins with fluorescent markers or other biochemical probes, facilitating the observation of protein interactions, localization, and trafficking within cells. Beyond protein research, thiol-reactive agents are utilized in creating biosensors and developing targeted drug delivery systems, where the precision of thiol-based reactions ensures the correct attachment of agents to specific molecular targets. In materials science, thiol-reactive chemicals are employed to engineer surfaces with specific properties, such as increased biocompatibility or enhanced catalytic activity. Their high reactivity and specificity make them invaluable for crafting molecular assemblies and nanostructures that are fundamental in the development of nanotechnology and biotechnology applications. The unique properties of thiol groups, including their redox-reactivity and ability to form disulfide bonds, also make thiol-reactive compounds ideal for designing dynamic materials that can respond to environmental stimuli. This adaptability has wide-ranging implications for research in environmental science, where they are used to detect and neutralize toxic substances. View detailed information on our available Thiol-reactive compounds by clicking on the product name.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

6-Iodoacetamidotetramethyl Rhodamine (Technical grade)

159435-00-4sc-500883
0.5 mg
$372.00
(0)

6-Iodoacetamidotetramethyl Rhodamine is a thiol-reactive compound characterized by its strong electrophilic properties, enabling it to form covalent bonds with thiol groups. This reactivity is influenced by the presence of the iodoacetamido group, which enhances its specificity and efficiency in targeting thiols. The compound exhibits distinct fluorescence characteristics, allowing for sensitive detection in various biochemical assays. Its unique molecular structure facilitates diverse interactions, making it a versatile tool in chemical biology.