Santa Cruz Biotechnology offers a variety of gene editing products to target structural proteins using the CRISPR/Cas9 system. Structural proteins are essential for maintaining the overall structural integrity of cells. Proteins which maintain structural integrity also ensure proper locomotion of the cell, which is essential for pinocytosis, phagocytosis and cytokinesis. Cell structure influences cell surface adhesion and migration, both of which are important factors in cancer metastasis. In addition to cytoskeletal organization, structural proteins play a critical role in cell differentiation and tissue specialization. Structural proteins also play various roles in stabilizing actin filaments, thereby contributing to actin polymerization and reorganization. To knockdown expression of structural proteins, Santa Cruz Biotechnology offers target-specific CRISPR/Cas9 Knockout (KO) Plasmids and CRISPR Double Nickase Plasmids.To activate transcription of structural protein genes, Santa Cruz Biotechnology offers target-specific CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems.
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