SLC7A10 Activators

SLC7A10 activators are a class of compounds that directly enhance the functional activity of SLC7A10 protein through specific signaling pathways or biological processes. These compounds act by directly or indirectly activating the protein, leading to increased functional activity.

One mechanism involves the activation of specific signaling pathways. For example, L-arginine enhances the functional activity of SLC7A10 protein through the arginine-NO pathway. L-arginine serves as a substrate for nitric oxide synthase (NOS), leading to the production of nitric oxide (NO). NO then activates guanylate cyclase, increasing the levels of cyclic guanosine monophosphate (cGMP). Increased cGMP levels enhance the functional activity of SLC7A10 protein, promoting its transport function. Another mechanism involves the modulation of intracellular signaling cascades. For instance, L-lysine activates the mechanistic target of rapamycin (mTOR) signaling pathway, leading to increased expression of SLC7A10. Activation of mTOR enhances protein synthesis, including the synthesis of SLC7A10, thereby enhancing its functional activity.