Date published: 2025-10-21

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PLK4 Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of PLK4 monoclonal antibodies for research in cell cycle regulation and mitotic processes. PLK4 monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). PLK4, or Polo-like kinase 4, plays a critical role in centriole biogenesis and is essential for proper cell division. Dysregulation of PLK4 has been implicated in various cancers, making it a significant target for therapeutic intervention and a key focus in cancer research. Understanding PLK4 function can provide insights into the mechanisms of tumorigenesis and potential strategies for treatment. Researchers worldwide utilize PLK4 monoclonal antibodies to investigate cellular division mechanisms and their relationship to cancer development. The high specificity of PLK4 monoclonal antibodies enables precise detection and analysis of protein expression patterns in diverse experimental settings. Santa Cruz Biotechnology monoclonal antibodies for PLK4 support researchers in advancing our understanding of cell cycle regulation and contributing to breakthrough discoveries in cancer biology.

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PLK4 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

SAK/STK18/PLK4 Antibody (D-6)

sc-518222mouse IgG1 κ241-264 (h)WB, IP, IF, ELISAh

new

(1)

SAK/STK18/PLK4 Antibody (19-Y7)

sc-100413mouse IgG1 κ1-110 (h)WB, IP, ELISAh
1
(3)

PLK4 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SAK/STK18/PLK4 CRISPR/Cas9 KO Plasmid (h)

sc-416389hGene KnockoutGFP0
(0)

SAK/STK18/PLK4 HDR Plasmid (h)

sc-416389-HDRhHomology Directed RepairPuromycin0
(0)

SAK/STK18/PLK4 Double Nickase Plasmid (h)

sc-416389-NIChGene KnockoutPuromycin0
(0)

SAK/STK18/PLK4 Double Nickase Plasmid (h2)

sc-416389-NIC-2hGene KnockoutPuromycin0
(0)

SAK/STK18/PLK4 CRISPR/Cas9 KO Plasmid (m)

sc-423195mGene KnockoutGFP0
(0)

SAK/STK18/PLK4 HDR Plasmid (m)

sc-423195-HDRmHomology Directed RepairPuromycin0
(0)

SAK/STK18/PLK4 Double Nickase Plasmid (m)

sc-423195-NICmGene KnockoutPuromycin0
(0)

SAK/STK18/PLK4 Double Nickase Plasmid (m2)

sc-423195-NIC-2mGene KnockoutPuromycin0
(0)

PLK4 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SAK/STK18/PLK4 CRISPR Activation Plasmid (h)

sc-416389-ACThGene ActivationPuro, Blast, Hygro0
(0)

SAK/STK18/PLK4 CRISPR Activation Plasmid (h2)

sc-416389-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

SAK/STK18/PLK4 Lentiviral Activation Particles (h)

sc-416389-LAChGene ActivationPuro, Blast, Hygro0
(0)

SAK/STK18/PLK4 Lentiviral Activation Particles (h2)

sc-416389-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

SAK/STK18/PLK4 CRISPR Activation Plasmid (m)

sc-423195-ACTmGene ActivationPuro, Blast, Hygro0
(0)

SAK/STK18/PLK4 CRISPR Activation Plasmid (m2)

sc-423195-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

SAK/STK18/PLK4 Lentiviral Activation Particles (m)

sc-423195-LACmGene ActivationPuro, Blast, Hygro0
(0)

SAK/STK18/PLK4 Lentiviral Activation Particles (m2)

sc-423195-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PLK4 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

SAK/STK18/PLK4 siRNA (h)

sc-61491hGene SilencingN/A0
(0)

SAK/STK18/PLK4 shRNA Plasmid (h)

sc-61491-SHhGene SilencingPuromycin0
(0)

SAK/STK18/PLK4 shRNA (h) Lentiviral Particles

sc-61491-VhGene SilencingPuromycin0
(0)

SAK/STK18/PLK4 siRNA (m)

sc-61492mGene SilencingN/A0
(0)

SAK/STK18/PLK4 shRNA Plasmid (m)

sc-61492-SHmGene SilencingPuromycin0
(0)

SAK/STK18/PLK4 shRNA (m) Lentiviral Particles

sc-61492-VmGene SilencingPuromycin0
(0)