RB3 activators represent a distinctive class of chemical compounds with a unique molecular structure designed to modulate specific biological pathways. These activators are characterized by their ability to interact with and enhance the activity of the RB3 protein, a key player in cellular processes. The molecular architecture of RB3 activators is finely tuned to engage with the binding sites on the RB3 protein, triggering conformational changes that result in an upregulation of its functional activity. Through this targeted interaction, RB3 activators play a crucial role in the intricate signaling networks within cells.
RB3 activators involves their selective binding to the RB3 protein, a member of the retinoblastoma protein family. This interaction induces a cascade of molecular events that modulate cellular functions such as cell cycle progression, DNA replication, and apoptosis. By specifically engaging with RB3, these activators influence cellular responses to various environmental cues, contributing to the intricate regulation of cell fate. The design and synthesis of RB3 activators involve a deep understanding of the structural and functional aspects of the RB3 protein, emphasizing the precision required in developing molecules within this chemical class. Ongoing research in this field aims to elucidate the full scope of cellular processes influenced by RB3 activators, providing valuable insights into the intricate mechanisms that govern cellular behavior.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Guanosine 5′-diphosphate sodium salt hydrate (GDP) | 146-91-8 non-salt | sc-507402 | 10 mg | $645.00 | ||
GDP is bound by inactive Rab3 proteins. Conversion of GDP to GTP within the Rab3 protein triggers its activation. | ||||||
Calcium | 7440-70-2 | sc-252536 | 5 g | $209.00 | ||
Increased intracellular Ca2+ concentration triggers the activation of Rab3 proteins, as they are involved in calcium-dependent exocytosis. | ||||||
N-Ethylmaleimide | 128-53-0 | sc-202719A sc-202719 sc-202719B sc-202719C sc-202719D | 1 g 5 g 25 g 100 g 250 g | $22.00 $69.00 $214.00 $796.00 $1918.00 | 19 | |
N-Ethylmaleimide inactivates NSF (N-ethylmaleimide Sensitive Factor), an ATPase involved in vesicle fusion. Inhibition of NSF indirectly affects Rab3 activation and function. | ||||||
ADP | 58-64-0 | sc-507362 | 5 g | $54.00 | ||
ATP provides the energy necessary for the GTP/GDP exchange on Rab3 proteins, a key step in their activation. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates Protein Kinase C (PKC), which can phosphorylate and therefore modulate the role of Rab3 proteins in vesicle transport. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin increases the cellular levels of cAMP, which can indirectly modulate the activity of Rab3 proteins. | ||||||