Date published: 2026-1-9

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PNPO Antibodies

Santa Cruz Biotechnology delivers a wide array of PNPO monoclonal antibodies for research focused on understanding PNPO protein functions. PNPO monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). PNPO, or pyridoxamine 5'-phosphate oxidase, plays a crucial role in the metabolism of vitamin B6, facilitating the conversion of pyridoxamine 5'-phosphate to pyridoxal 5'-phosphate, the active form of vitamin B6. PNPO is essential for numerous enzymatic reactions, influencing amino acid metabolism and neurotransmitter synthesis. Research has shown that PNPO deficiency can lead to various neurological disorders and developmental delays. Understanding PNPO function provides valuable insights into vitamin B6-dependent processes and associated pathological conditions. Investigating PNPO activity helps researchers explore potential therapeutic approaches for vitamin B6-related disorders. Current studies continue to reveal new aspects of PNPO's involvement in cellular metabolism and disease progression. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of PNPO's role in health and disease.

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PNPO Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PNPO Antibody (E-8)

sc-393561mouse IgG1 κ157-261 (h)WB, IP, IF, ELISAm, r, h

new

(2)

PNPO CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PNPO CRISPR/Cas9 KO Plasmid (h)

sc-408250hGene KnockoutGFP0
(0)

PNPO HDR Plasmid (h)

sc-408250-HDRhHomology Directed RepairPuromycin0
(0)

PNPO Double Nickase Plasmid (h)

sc-408250-NIChGene KnockoutPuromycin0
(0)

PNPO Double Nickase Plasmid (h2)

sc-408250-NIC-2hGene KnockoutPuromycin0
(0)

PNPO CRISPR/Cas9 KO Plasmid (m)

sc-430481mGene KnockoutGFP0
(0)

PNPO HDR Plasmid (m)

sc-430481-HDRmHomology Directed RepairPuromycin0
(0)

PNPO Double Nickase Plasmid (m)

sc-430481-NICmGene KnockoutPuromycin0
(0)

PNPO Double Nickase Plasmid (m2)

sc-430481-NIC-2mGene KnockoutPuromycin0
(0)

PNPO CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PNPO CRISPR Activation Plasmid (h)

sc-408250-ACThGene ActivationPuro, Blast, Hygro0
(0)

PNPO CRISPR Activation Plasmid (h2)

sc-408250-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PNPO Lentiviral Activation Particles (h)

sc-408250-LAChGene ActivationPuro, Blast, Hygro0
(0)

PNPO Lentiviral Activation Particles (h2)

sc-408250-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PNPO CRISPR Activation Plasmid (m)

sc-430481-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PNPO CRISPR Activation Plasmid (m2)

sc-430481-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PNPO Lentiviral Activation Particles (m)

sc-430481-LACmGene ActivationPuro, Blast, Hygro0
(0)

PNPO Lentiviral Activation Particles (m2)

sc-430481-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

PNPO siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PNPO siRNA (h)

sc-76182hGene SilencingN/A0
(0)

PNPO shRNA Plasmid (h)

sc-76182-SHhGene SilencingPuromycin0
(0)

PNPO shRNA (h) Lentiviral Particles

sc-76182-VhGene SilencingPuromycin0
(0)

PNPO siRNA (m)

sc-76183mGene SilencingN/A0
(0)

PNPO shRNA Plasmid (m)

sc-76183-SHmGene SilencingPuromycin0
(0)

PNPO shRNA (m) Lentiviral Particles

sc-76183-VmGene SilencingPuromycin0
(0)