Neuropeptide S Activators
Neuropeptide S Activators as a chemical class encompasses compounds that can modulate the activity of the NPS/NPSR1 signaling pathway. The influence of these activators can be exerted through a range of biochemical interactions, which may include altering intracellular second messenger levels, modifying neurotransmitter release or reuptake, or affecting the expression levels of the NPS receptor itself. These compounds, by acting on various components of the signaling cascade, can indirectly enhance or upregulate the action of NPS.
The activation of NPS-related pathways by these chemicals may result from increased intracellular cyclic AMP levels, as seen with forskolin and rolipram, which is known to enhance the activity of protein kinase A (PKA) and can lead to the phosphorylation of various proteins that modulate receptor activity and neurotransmission. Others, like caffeine or nicotine, may indirectly influence the NPS system through their primary actions on neurotransmitter systems that are known to interact with or modulate the physiological responses attributed to NPS.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Adenylyl cyclase activator that raises cAMP levels, potentially enhancing NPSR1 activity by promoting receptor expression or function. | ||||||
Fluoxetine hydrochloride | 56296-78-7 | sc-201125 sc-201125A sc-201125B sc-201125C | 50 mg 250 mg 1 g 5 g | $77.00 $213.00 $407.00 $849.00 | 14 | |
Selective serotonin reuptake inhibitor that can influence serotonergic pathways, possibly affecting NPSR1 modulated systems. | ||||||
L-Theanine | 3081-61-6 | sc-204787 sc-204787A | 1 g 5 g | $58.00 $142.00 | 1 | |
Amino acid that may affect glutamatergic signaling, which could modulate the NPS system indirectly. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Adenosine receptor antagonist that can increase neurotransmitter release, potentially enhancing NPSR1 signaling indirectly. | ||||||
Modafinil | 68693-11-8 | sc-507327 | 10 mg | $99.00 | ||
Agent that promotes wakefulness, possibly affecting downstream effects of NPSR1 signaling. | ||||||
Olanzapine | 132539-06-1 | sc-212469 | 100 mg | $133.00 | 6 | |
Atypical antipsychotic known to interact with multiple neurotransmitter receptors, which may indirectly affect NPSR1 signaling. | ||||||
Yohimbine hydrochloride | 65-19-0 | sc-204412 sc-204412A sc-204412B | 1 g 5 g 25 g | $51.00 $171.00 $530.00 | 2 | |
Alpha-2 adrenergic receptor antagonist that can increase noradrenergic transmission, possibly affecting NPS activity. | ||||||
Reserpine | 50-55-5 | sc-203370 sc-203370A | 1 g 5 g | $137.00 $414.00 | 1 | |
Indole alkaloid that depletes monoamine neurotransmitters, potentially modulating systems regulated by NPS. | ||||||
Haloperidol | 52-86-8 | sc-507512 | 5 g | $190.00 | ||
Dopamine D2 receptor antagonist, could indirectly affect dopaminergic pathways intersecting with NPS/NPSR1 signaling. | ||||||