MYBPH Inhibitors

MYBPH (Myosin-binding protein H) inhibitors represent a class of compounds that exert their biochemical effects through the inhibition of the MYBPH protein. MYBPH is a crucial regulatory protein involved in the function of striated muscle, particularly in cardiac and skeletal muscle tissues. This protein plays a pivotal role in the modulation of muscle contraction and relaxation by binding to myosin, a motor protein responsible for muscle contraction. By binding to myosin, MYBPH fine-tunes the mechanical properties of muscle contraction, contributing to the overall control of muscle function.

Inhibitors of MYBPH are designed to interfere with the interaction between MYBPH and myosin, disrupting the normal regulatory processes that govern muscle contraction. These compounds may act by binding to specific regions of MYBPH or altering its conformation, ultimately reducing its ability to bind to myosin effectively. As a consequence, MYBPH inhibitors can lead to alterations in muscle contractility and relaxation, potentially affecting muscle performance.