Date published: 2026-4-24

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MCPIP Inhibitors

MCPIP inhibitors belong to a chemical class of compounds that specifically target the activity of MCPIP (Monocyte Chemoattractant Protein Induced Protein), a key regulatory enzyme involved in various cellular processes. These inhibitors are designed to selectively bind to and inhibit the function of MCPIP, thereby modulating its biological activity. MCPIP inhibitors are typically small organic molecules that are structurally optimized to interact with the active site of the MCPIP enzyme, interfering with its catalytic function. By blocking MCPIP activity, these inhibitors can affect downstream signaling pathways and cellular responses that are regulated by MCPIP.

The development of MCPIP inhibitors involves a comprehensive understanding of the enzyme's structure, function, and its role in cellular processes. Through careful design and synthesis, researchers aim to create potent and selective MCPIP inhibitors that can be used as valuable tools for studying the physiological and pathological functions of MCPIP in various cellular contexts. The discovery and characterization of MCPIP inhibitors offer significant insights into the intricate molecular mechanisms underlying cellular processes influenced by MCPIP, opening up new avenues for research.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Triptolide

38748-32-2sc-200122
sc-200122A
1 mg
5 mg
$90.00
$204.00
13
(1)

Triptolide is a potent inhibitor of MCPIP. It has been shown to suppress MCPIP expression and attenuate inflammatory responses.

BAY 11-7082

19542-67-7sc-200615B
sc-200615
sc-200615A
5 mg
10 mg
50 mg
$62.00
$85.00
$356.00
155
(1)

This synthetic compound inhibits the activity of MCPIP by blocking NF-κB signaling. It has been extensively studied for its anti-inflammatory properties.

Parthenolide

20554-84-1sc-3523
sc-3523A
50 mg
250 mg
$81.00
$306.00
32
(2)

Parthenolide exerts anti-inflammatory effects by inhibiting MCPIP-induced cytokine production.

Honokiol

35354-74-6sc-202653
sc-202653A
10 mg
25 mg
$118.00
$178.00
4
(1)

Honokiol has been identified as an MCPIP inhibitor. It can suppress MCPIP expression and reduce inflammation in various models.

Baicalein

491-67-8sc-200494
sc-200494A
sc-200494B
sc-200494C
10 mg
100 mg
500 mg
1 g
$32.00
$42.00
$162.00
$292.00
12
(1)

Baicalein possesses MCPIP inhibitory effects. It can attenuate inflammation by inhibiting MCPIP-induced cytokine expression.