Date published: 2026-4-1

1-800-457-3801

SCBT Portrait Logo
Seach Input

LCE3C Activators

LCE3C Activators designate a category of chemical compounds identified for their ability to modulate the activity of the LCE3C gene. LCE3C, or Late Cornified Envelope 3C, is a gene that encodes proteins involved in the formation of the cornified cell envelope, a crucial structural component of the skin. This envelope plays a fundamental role in maintaining skin barrier integrity and protection against external environmental factors. Activators of LCE3C are molecules that possess the capacity to either enhance the expression of the LCE3C gene or potentiate its biological activity within a cell. These compounds serve as essential tools for researchers interested in deciphering the biological significance of LCE3C and its potential involvement in skin biology and barrier function.

The precise mechanisms through which LCE3C activators exert their effects are currently a subject of active scientific investigation. These molecules may act at the transcriptional or post-transcriptional level, potentially influencing the production of LCE3C proteins or modifying their interactions with other cellular components involved in the cornified cell envelope assembly. By manipulating LCE3C activity, researchers aim to uncover its roles in skin homeostasis, barrier function, and responses to external stressors. Exploring LCE3C activators could provide valuable insights into the molecular pathways and cellular processes controlled by this gene, contributing to a deeper understanding of its significance in normal skin physiology and potentially leading to novel discoveries in the fields of dermatology and molecular biology.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic acid, involved in skin differentiation, might upregulate LCE3C as part of its role in enhancing skin barrier formation and repair by promoting the differentiation of keratinocytes.

1α,25-Dihydroxyvitamin D3

32222-06-3sc-202877B
sc-202877A
sc-202877C
sc-202877D
sc-202877
50 µg
1 mg
5 mg
10 mg
100 µg
$220.00
$645.00
$1000.00
$1500.00
$440.00
32
(2)

The active form of Vitamin D3 can induce keratinocyte differentiation, potentially leading to increased LCE3C expression in processes related to skin barrier formation and maintenance.

(−)-Epigallocatechin Gallate

989-51-5sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$43.00
$73.00
$126.00
$243.00
$530.00
$1259.00
11
(1)

EGCG, with antioxidant properties, might influence LCE3C expression by modulating cellular responses to oxidative stress, which is known to affect skin barrier homeostasis and repair.

Hyaluronic acid

9004-61-9sc-337865
10 mg
$208.00
(0)

Hyaluronic acid, involved in skin hydration and repair, might indirectly stimulate LCE3C expression by enhancing keratinocyte activity and promoting skin barrier recovery processes.

Glycolic acid solution

79-14-1sc-215102
sc-215102A
25 g
500 g
$38.00
$60.00
(0)

Used in skin care for exfoliation, glycolic acid might upregulate LCE3C by stimulating epidermal renewal and repair, which involves the cornified envelope proteins.

Nicotinamide

98-92-0sc-208096
sc-208096A
sc-208096B
sc-208096C
100 g
250 g
1 kg
5 kg
$44.00
$66.00
$204.00
$831.00
6
(1)

As a form of vitamin B3, niacinamide can improve skin barrier function, potentially enhancing LCE3C expression as part of its effects on keratinocyte differentiation and lipid synthesis.

Urea

57-13-6sc-29114
sc-29114A
sc-29114B
1 kg
2 kg
5 kg
$31.00
$43.00
$78.00
17
(1)

A component of the skin's natural moisturizing factor, urea might enhance LCE3C expression by modulating skin hydration and keratinocyte function, particularly in dry skin conditions.

L-Ascorbic acid, free acid

50-81-7sc-202686
100 g
$46.00
5
(1)

Vitamin C, an antioxidant, might influence LCE3C expression through its role in collagen synthesis and skin repair, potentially affecting pathways involved in skin barrier function.