Histaminergics

We now offer a broad range of Histaminergics. Histamine is a key molecule involved in a number of physiological processes, ranging from regulation of the sleep-wake cycle to gastric acid release. Among the most studied processes involving histamine is the immune response to foreign pathogens. Release of histamine is triggered when the cellular membranes of the basophils and mast cells where histamine is stored are bound by IgE antibodies. Upon release, histamine binds to a class of receptors called G protein-coupled histamine receptors, inducing a multitude of effects that vary depending on the specific receptor and location. These effects include increasing capillary permeability to white blood cells and select protein as part of the immune response. Histaminergics include compounds that can stimulate or antagonize this response, and are useful for investigating further effects of histamine in physiological systems. Our popular products such as Ketotifen fumarate, Loratadine, and Diphenhydramine hydrochloride are typically available for immediate shipment. View detailed information on all our available Histaminergics by linking to the specific product blocks.

PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
Ketotifen fumarate
A histamine H1 antagonist and mast cell growth inhibitor
34580-14-8 sc-201094
sc-201094A
1 g
100 mg
$62.00
$39.00
3
(1)
Loratadine
Loratadine is a peripheral histamine H1 receptor agonist
79794-75-5 sc-203117
sc-203117A
10 mg
50 mg
$105.00
$446.00
1
(1)
Ranitidine
Ranitidine is a selective and competitive histamine H2 receptor inhibitor
66357-35-5 sc-203679
1 g
$180.00
0
(1)
Astemizole
Astemizole is a potent and selective H1-receptor antagonist that displays antihistamine and antimalarial activity
68844-77-9 sc-201088
sc-201088A
10 mg
50 mg
$69.00
$275.00
3
(1)
2-Pyridylethylamine dihydrochloride
2-Pyridylethylamine dihydrochloride is a histamine H1 receptor agonist that produces vasoconstriction
3343-39-3 sc-203467
50 mg
$80.00
0
(0)
Dimaprit dihydrochloride
Dimaprit dihydrochloride is a specific agonist of the histamine H2-receptor
23256-33-9 sc-201090
100 mg
$94.00
0
(0)
Imetit dihydrobromide
Imetit dihydrobromide is a high affinity agonist at the histamine H3- and H4-receptors
32385-58-3 sc-203602
10 mg
$110.00
0
(0)
HTMT dimaleate
HTMT dimaleate is a mixed H1/H2 histamine agonist that is significantly more potent than histamine itself
195867-54-0 sc-204003
sc-204003A
10 mg
50 mg
$149.00
$615.00
0
(0)
Mepyramine maleate
Mepyramine maleate is a histamine H1 receptor antagonist
59-33-6 sc-203629
sc-203629A
100 mg
1 g
$65.00
$220.00
1
(1)
Chlorpheniramine Maleate
Chlorpheniramine Maleate is an antagonist of the histamine H1-receptor
113-92-8 sc-204684
sc-204684A
5 g
25 g
$35.00
$83.00
1
(1)
Buclizine, Dihydrochloride
Buclizine, Dihydrochloride is an antihistamine used as an anti-emetic
129-74-8 sc-210969
50 mg
$260.00
0
(0)
N-Methyl-1H-imidazole-4-ethanamine dihydrochloride
N-Methyl-1H-imidazole-4-ethanamine dihydrochloride is a potent histamine receptor agonist
16503-22-3 sc-203638
sc-203638A
10 mg
50 mg
$107.00
$411.00
0
(0)
Brompheniramine Maleate
Brompheniramine Maleate is a histamine H1 receptors antagonist
980-71-2 sc-210967
sc-210967A
25 mg
250 mg
$100.00
$240.00
1
(1)
Doxepin hydrochloride
Doxepin hydrochloride is a highly potent histamine H1 antagonist with affinity to H4 receptor
1229-29-4 sc-203930
1 g
$50.00
0
(1)
L-Histidinol dihydrochloride
L-Histidinol dihydrochloride is A precursor of histamine and a reversible inhibitor of protein synthesis.
1596-64-1 sc-207801
1 g
$137.00
0
(1)
Hydroxyzine Dihydrochloride
Hydroxyzine Dihydrochloride is a hetercyclic H1 receptor antagonist
2192-20-3 sc-205716
sc-205716A
5 g
10 g
$75.00
$103.00
0
(0)
Antazoline hydrochloride
Antazoline hydrochloride is an anticholinergic and antihistamine agent
2508-72-7 sc-203515
sc-203515A
sc-203515B
100 mg
1 g
5 g
$65.00
$80.00
$200.00
0
(1)
Orphenadrine Citrate Salt
Orphenadrine Citrate Salt is a histaminergic compound
4682-36-4 sc-212481
5 g
$45.00
0
(0)
trans-Triprolidine hydrochloride
trans-Triprolidine hydrochloride is a potent H1 receptor antagonist
6138-79-0 sc-204354
1 g
$35.00
0
(1)
Clemastine fumarate
Clemastine fumarate is a selective histamine H1 antagonist
14976-57-9 sc-203897
100 mg
$95.00
0
(1)
Cimetidine
Cimetidine is an inhibitor of histamine binding to histamine H2 receptors
51481-61-9 sc-202996
sc-202996A
5 g
10 g
$62.00
$86.00
1
(1)
Ranitidine hydrochloride
Ranitidine hydrochloride is a histamine H2-receptor antagonist
66357-59-3 sc-204874
1 g
$32.00
0
(0)
Nizatidine
Nizatidine is an inhibitor of gastric acid secretion
76963-41-2 sc-205771
sc-205771A
5 g
10 g
$70.00
$134.00
0
(1)
Azelastine HCl
Azelastine HCl is an H1-receptor antagonist with antiallergic effects and disrupts TNF alpha activity
79307-93-0 sc-201096
sc-201096A
sc-201096B
sc-201096C
sc-201096D
100 mg
250 mg
1 g
5 g
10 g
$92.00
$200.00
$642.00
$1,950.00
$3,200.00
0
(1)
Levocabastine Hydrochloride
Levocabastine Hydrochloride is a histamine H1 receptor antagonist and anti-allergic agent
79547-78-7 sc-201095
10 mg
$184.00
4
(1)
Cetirizine Dihydrochloride
Cetirizine Dihydrochloride is a Histamine H1 receptor inverse agonist
83881-52-1 sc-202992
50 mg
$59.00
0
(0)
Ebastine
Ebastine is an antagonist of the histamine H1-receptor
90729-43-4 sc-205663
sc-205663A
1 g
5 g
$104.00
$420.00
2
(1)
Roxatidine Acetate Hydrochloride
Roxatidine Acetate Hydrochloride is an antagonist of the histamine H2-receptor
93793-83-0 sc-205844
sc-205844A
100 mg
500 mg
$80.00
$240.00
0
(1)
Dimebolin dihydrochloride
Dimebolin dihydrochloride is a histamine, AR, and Ca channel inhibitor
97657-92-6 sc-294348
sc-294348A
sc-294348B
1 mg
5 mg
50 mg
$37.00
$96.00
$384.00
0
(0)
Amthamine
Amthamine is a very selective agonist of the histamine H2-receptor
142437-67-0 sc-201087
5 mg
$84.00
0
(0)
Methimepip dihydrobromide
Methimepip dihydrobromide is a selective histamine H3 receptor agonist
151070-80-3 sc-204080
sc-204080A
10 mg
50 mg
$155.00
$670.00
1
(0)
Fexofenadine HCl
Fexofenadine HCl is an antihistamine that inhibits Cox-1, Cox-2, and is a histamine H1 receptor agonist
153439-40-8 sc-203047
sc-203047A
10 mg
50 mg
$95.00
$399.00
0
(0)
(+)-alpha-Methylhistamine dihydrobromide
(+)-α-Methylhistamine dihydrobromide is a less active enantiomer of H3 agonist R-(−)-α-methylhistamine
75614-93-6 sc-204426
sc-204426A
10 mg
50 mg
$119.00
$510.00
0
(0)
Inositol
Inositol is a component of membrane phospholipids
6917-35-7 sc-394417
100 g
$75.00
0
(0)
2-Methyl-3-carbethoxy-5,6-dihydropyran
CAS: 10226-28-5, MF: C9H14O3, MW: 170.21
10226-28-5 sc-394336
250 mg
$260.00
0
(0)
ICI 162,846
ICI 162,846 is a potent histamine H2 receptor antagonist
84545-30-2 sc-361207
50 mg
$200.00
0
(0)
DPPE Fumarate
DPPE Fumarate is a compound that inhibits histamine binding at the intracellular histamine (Hlc) site
98774-23-3 sc-205942
sc-205942A
10 mg
50 mg
$115.00
$440.00
0
(0)
Zolantidine dimaleate
Zolantidine dimaleate is a selective and penetrating H2 receptor inhibitor
104076-38-2 sc-364691
25 mg
$522.00
0
(0)
Aminopotentidine
Aminopotentidine is a histamine H2-receptor antagonist
140873-26-3 sc-203817A
sc-203817
sc-203817B
1 mg
5 mg
10 mg
$90.00
$185.00
$350.00
0
(0)
S15535
S15535 is a partial SR-1A (5-HT1A) receptor agonist
146998-34-7 sc-250959
5 mg
$200.00
0
(0)
2-(2-Methylaminoethyl)pyridine
2-(2-Methylaminoethyl)pyridine is a histidine analog and H1 receptor agonist
5638-76-6 sc-254040
5 g
$99.00
0
(0)
Sinomenine hydrochloride
Sinomenine hydrochloride is a natural anti-inflammatory morphinan analog
6080-33-7 sc-280083
25 mg
$225.00
0
(0)
2-[3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoic Acid Methyl Ester
2-[3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoic Acid Methyl Ester is a precursor to Montelukast
149968-11-6 sc-394339
25 mg
$280.00
0
(0)
Phenindamine Hydrochloride
Phenindamine Hydrochloride is a Histamine H1 receptor inhibitor
5503-08-2 sc-460196
50 mg
$320.00
0
(0)
Carbinoxamine Maleate Salt
Carbinoxamine Maleate Salt is an analgesic and anti-inflammatory compound
3505-38-2 sc-211015
100 mg
$187.00
0
(0)
Carebastine
Carebastine is an active caboxylic acid metabolite of Ebastine
90729-42-3 sc-211022
1 mg
$205.00
2
(1)