Santa Cruz Biotechnology offers a variety of gene editing products to target transport and trafficking proteins using the CRISPR/Cas9 system. Transport proteins facilitate the movement of a chemical across a biological lipid membrane. Transport proteins use either passive transport, in which no energy is required because movement is in the same direction as the electrochemical gradient, or active transport, in which energy input is necessary for movement against the electrochemical gradient. Active transport proteins fall into one of three categories: symporters, antiporters, and uniporters. Trafficking proteins help to mediate the movement of other proteins or small molecules accross and between cells. To knockdown expression of transport and trafficking proteins, Santa Cruz Biotechnology offers target-specific CRISPR/Cas9 Knockout (KO) Plasmids and CRISPR Double Nickase Plasmids.To activate transcription of transport and trafficking protein genes, Santa Cruz Biotechnology offers target-specific CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems.
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