Santa Cruz Biotechnology offers a variety of gene editing products to target neurobiology proteins using the CRISPR/Cas9 system. Neurobiology proteins are concerned with the structure and function of cells of the nervous system. Proper neuronal function relies on normal cellular growth as well as the tight regulation of neurotransmitters and their receptors. Changes in neurofilament phosphorylation or metabolism are frequently observed in neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), Parkinson's disease and Alzheimer's disease. To knockdown expression of neurobiology proteins, Santa Cruz Biotechnology offers target-specific CRISPR/Cas9 Knockout (KO) Plasmids and CRISPR Double Nickase Plasmids.To activate transcription of neurobiology protein genes, Santa Cruz Biotechnology offers target-specific CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems.