Date published: 2026-5-30

1-800-457-3801

SCBT Portrait Logo
Seach Input

GABAA R β 3 Activators

Santa Cruz Biotechnology now offers a broad range of GABA A Rβ3 Activators for use in various applications. GABA A receptors, particularly those containing the β3 subunit, are integral to the inhibitory neurotransmission system in the central nervous system. These receptors play a vital role in modulating neural excitability by mediating the effects of gamma-aminobutyric acid (GABA), the brain's primary inhibitory neurotransmitter. GABA A Rβ3 Activators are crucial tools in scientific research, allowing for the selective enhancement of these specific receptor subtypes to investigate their roles in neural function, synaptic transmission, and overall brain activity. By activating GABA A Rβ3, researchers can delve into the mechanisms of synaptic inhibition, explore the modulation of neuronal circuits, and gain insights into how these receptors contribute to processes such as anxiety regulation, sensory processing, and motor control. These activators are widely employed in electrophysiological studies and behavioral experiments to understand the intricate dynamics of GABAergic signaling in the brain. The availability of these activators has significantly advanced research in neurobiology and neuroscience, providing essential tools for exploring the complex regulatory mechanisms of inhibitory neurotransmission. View detailed information on our available GABA A Rβ3 Activators by clicking on the product name.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Etifoxine Hydrochloride

56776-32-0sc-358742
10 mg
$196.00
(0)

Etifoxine Hydrochloride acts as a selective allosteric modulator of GABAA receptors, specifically targeting the beta-3 subunit. This compound alters the conformational dynamics of the receptor, promoting a unique binding affinity that stabilizes the open state. Its interaction with lipid bilayers is influenced by its amphiphilic characteristics, facilitating membrane penetration and influencing receptor localization. The compound's kinetic behavior showcases a rapid onset of action, contributing to its distinct pharmacodynamic profile.

Muscimol

2763-96-4sc-200460
sc-200460A
5 mg
25 mg
$161.00
$537.00
2
(1)

Muscimol is a direct agonist of the GABAA receptor. By binding to the GABA binding site on the receptor, it enhances the receptor's response to GABA, leading to increased activation of GABAA Rβ3.

Etomidate

33125-97-2sc-203577
10 mg
$126.00
(0)

Etomidate is a positive allosteric modulator of the GABAA receptor. It enhances the receptor's response to GABA, leading to increased activation of GABAA Rβ3.

Isoflurane

26675-46-7sc-470926
sc-470926A
5 g
25 g
$69.00
$219.00
7
(1)

Isoflurane is a positive allosteric modulator of the GABAA receptor. It enhances the receptor's response to GABA, leading to increased activation of GABAA Rβ3.