Date published: 2025-9-30

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Fluorogenic Substrates

Santa Cruz Biotechnology now offers a broad range of Fluorogenic Substrates for use in various applications. Fluorogenic substrates are specialized molecules designed to release a fluorescent signal in response to specific biochemical interactions. This characteristic makes them invaluable tools in the field of biochemistry and molecular biology, especially in the study of enzyme activities, substrate specificity, and kinetic properties. Researchers rely on these substrates to monitor real-time reactions within cells and tissues, enabling the visualization of processes that were previously invisible with conventional techniques. These substrates have revolutionized the approach to studying cellular mechanisms, offering a dynamic way to observe the activation and regulation of enzymes in situ. They are extensively used in high-throughput screening to identify potential modulators of enzyme activity, providing insights that are critical in fields like genetics, enzymology, and molecular signaling pathways. Furthermore, fluorogenic substrates are utilized in environmental monitoring and diagnostics, aiding in the detection of specific enzymes or microbial contaminants. The application of these substrates extends into material science as well, where they help in the development of new fluorescent materials with advanced properties. The versatility and specificity of fluorogenic substrates continue to make them a cornerstone in experimental science, facilitating a deeper understanding of complex biological systems through vivid, real-time imaging. View detailed information on our available Fluorogenic Substrates by clicking on the product name.

Items 121 to 130 of 147 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

L-Arginyl-L-arginine 7-amido-4- methylcoumarin trihydrochloride

201847-69-0sc-281540
sc-281540A
10 mg
25 mg
$139.00
$251.00
(0)

L-Arginyl-L-arginine 7-amido-4-methylcoumarin trihydrochloride is a fluorogenic compound characterized by its ability to undergo specific hydrolysis reactions, leading to the release of a highly fluorescent product. Its unique coumarin moiety facilitates strong intramolecular interactions, enhancing fluorescence intensity. The compound's reactivity with various nucleophiles is governed by its distinct electronic properties, allowing for precise monitoring of biochemical processes through fluorescence modulation.

[Ru(bpy)2(5-iodoacetamido-1,10-phenanthroline)](PF6)2

204273-39-2sc-396635
sc-396635A
10 mg
100 mg
$205.00
$1761.00
(0)

Ru(bpy)2(5-iodoacetamido-1,10-phenanthroline)(PF6)2 is a fluorogenic complex notable for its robust luminescent properties, driven by the unique coordination of ruthenium with bipyridine ligands. The presence of the iodoacetamido group enhances its reactivity towards biomolecules, facilitating selective interactions that can modulate fluorescence. This compound exhibits distinct photophysical behavior, including efficient energy transfer and tunable emission spectra, making it a versatile tool for probing molecular environments.

[Ru(bpy)2(5-chloroacetamido-1,10-phenanthroline)](PF6)2

204273-42-7sc-396634
10 mg
$205.00
(0)

Ru(bpy)2(5-chloroacetamido-1,10-phenanthroline)(PF6)2 is a distinctive fluorogenic complex characterized by its strong luminescence and unique electronic properties. The chlorinated acetamido moiety introduces specific steric and electronic effects, enhancing its interaction with target molecules. This compound demonstrates remarkable stability under varying conditions and exhibits a pronounced sensitivity to environmental changes, allowing for precise monitoring of molecular dynamics through fluorescence modulation.

6-TET dipivaloate

314734-87-7sc-396586
500 mg
$290.00
(0)

6-TET dipivaloate is a notable fluorogenic compound that exhibits unique photophysical properties due to its specific molecular structure. The presence of dipivaloyl groups enhances its solubility and stability, facilitating efficient energy transfer processes. Its reactivity as an acid halide allows for selective interactions with nucleophiles, leading to distinct fluorescence responses. This compound's ability to undergo rapid reaction kinetics makes it an intriguing candidate for studying dynamic molecular interactions in various environments.

6,7-Diethoxy-4-methylcoumarin

314744-06-4sc-291434
500 mg
$700.00
(0)

6,7-Diethoxy-4-methylcoumarin is a distinctive fluorogenic compound characterized by its unique coumarin backbone, which enables strong intramolecular interactions. The diethoxy substituents enhance its photostability and fluorescence quantum yield, allowing for efficient light absorption and emission. Its reactivity profile showcases selective interactions with various chemical species, resulting in notable fluorescence changes. This compound's rapid photochemical kinetics make it an interesting subject for exploring molecular dynamics and environmental sensing.

Hoechst 34580

911004-45-0sc-396575
sc-396575A
5 mg
50 mg
$105.00
$500.00
2
(0)

Hoechst 34580 is a specialized fluorogenic dye known for its high affinity for nucleic acids, particularly DNA. Its unique structure facilitates intercalation between base pairs, leading to significant fluorescence enhancement upon binding. This compound exhibits remarkable photophysical properties, including a sharp emission spectrum and high quantum yield. The dye's selective binding dynamics and rapid response to environmental changes make it a valuable tool for studying nucleic acid interactions and cellular processes.

6-HEX dipivaloate

1166837-63-3sc-396590
25 mg
$185.00
(0)

6-HEX dipivaloate is a fluorogenic compound characterized by its ability to undergo specific molecular interactions that enhance fluorescence. Its unique ester groups facilitate hydrophobic interactions, promoting selective binding to target molecules. The compound exhibits distinct reaction kinetics, with rapid fluorescence activation upon interaction with certain substrates. Additionally, its stability under varying conditions allows for consistent performance in diverse environments, making it an intriguing subject for studying molecular dynamics.

(+)-Biotin 4-Amidobenzoic Acid, Sodium Salt

102418-74-6sc-207358
sc-207358A
sc-207358B
sc-207358C
100 mg
250 mg
500 mg
1 g
$325.00
$726.00
$1122.00
$1889.00
(1)

(+)-Biotin 4-Amidobenzoic Acid, Sodium Salt is a fluorogenic compound notable for its unique ability to form strong hydrogen bonds, enhancing its fluorescence properties. The presence of the amidobenzoic acid moiety allows for specific interactions with biomolecules, leading to increased signal intensity. Its ionic nature contributes to solubility in aqueous environments, facilitating rapid diffusion and interaction kinetics, making it a compelling candidate for exploring molecular recognition processes.

4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside

229644-17-1sc-220956
5 mg
$388.00
(1)

4-Methylumbelliferyl 6-thio-palmitate-β-D-glucopyranoside is a fluorogenic compound characterized by its unique thioester linkage, which enhances its reactivity in enzymatic assays. The palmitate chain promotes hydrophobic interactions, facilitating membrane penetration and substrate specificity. Its β-D-glucopyranoside structure allows for selective enzymatic cleavage, resulting in a significant increase in fluorescence. This compound exhibits rapid reaction kinetics, making it ideal for real-time monitoring of enzymatic activity.

4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-α-D-glucopyranoside Potassium Salt

210357-37-2sc-397321
1 mg
$325.00
(0)

4-Methylumbelliferyl 6-Sulfo-2-acetamido-2-deoxy-α-D-glucopyranoside Potassium Salt is a fluorogenic substrate notable for its sulfonate group, which enhances solubility and ionic interactions in aqueous environments. The α-D-glucopyranoside configuration allows for specific enzyme recognition, leading to efficient hydrolysis. Upon enzymatic cleavage, a pronounced fluorescence shift occurs, enabling sensitive detection. Its rapid turnover rate supports dynamic studies of enzymatic processes.