Erg Inhibitors
Erg inhibitors belong to a specific chemical class of compounds designed to target and inhibit the activity of ETS-related gene (Erg), a transcription factor that plays a significant role in regulating gene expression during development and differentiation of various tissues. Erg belongs to the ETS family of transcription factors and is involved in the control of cell proliferation, differentiation, and maintenance of tissue homeostasis.
Erg inhibitors work by specifically targeting the Erg transcription factor, interfering with its ability to bind to DNA and regulate the expression of target genes. By doing so, these inhibitors may modulate the transcriptional programs that govern cellular processes and tissue development. Research into Erg inhibitors is ongoing to unravel their precise mechanisms of action and explore their implications in understanding transcriptional regulation and cellular differentiation. The study of Erg inhibitors contributes to a deeper understanding of the intricate mechanisms governing tissue-specific gene expression and cellular identity.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bisphenol A | 80-05-7 | sc-391751 sc-391751A | 100 mg 10 g | $300.00 $490.00 | 5 | |
Bisphenol A (3-chloro-2-hydroxypropyl) (2,3-dihydroxypropyl) ether is a small molecule inhibitor that targets the DNA binding activity of ERG and other ETS transcription factors. It works by disrupting the interaction between ERG and its target DNA sequences, potentially affecting the transcriptional regulation of genes involved in various cellular processes. | ||||||
PFI-1 | 1403764-72-6 | sc-478504 | 5 mg | $96.00 | ||
PFI-1 is a small molecule inhibitor that targets the protein-protein interactions of ERG with bromodomain proteins. By disrupting these interactions, PFI-1 may affect the recruitment of ERG to specific genomic regions and the subsequent transcriptional regulation of genes involved in cancer progression. | ||||||