DNA Methylation
Santa Cruz Biotechnology now offers a broad range of DNA Methylation products. DNA Methylation products include compounds which can methylate DNA themselves or act as cofactors for enzyme-catalyzed methylation. Additionally, they include activators and inhibitors of DNA methyltransferases, such as Dnmt and MGMT. DNA methyltransferases help maintain genomic stability by repairing damage and helping prevent mismatch errors from occurring. Research has implicated several mutations affecting these enzymes in the growth and development of various cancers. Our popular products such as Streptozotocin (U-9889), Sinefungin, and S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt are typically available for immediate shipment.
indicates a highly recommended product based on customer preference.
| PRODUCT NAME/Application | CAS | Catalog # | QUANTITY | Price | Citations | RATING | |
|---|---|---|---|---|---|---|---|
Streptozotocin (U-9889)Streptozotocin (U-9889) is an N-nitroso containing antibiotic and can be used as a potent DNA methylating agent. |
18883-66-4 |
sc-200719 sc-200719A |
1 g 5 g |
$104.00
$500.00 |
135 |
| |
5-Aza-2′-Deoxycytidine5-Aza-2′-Deoxycytidine is a DNMT inhibitor shown to alter gene expression. |
2353-33-5 |
sc-202424 sc-202424A sc-202424B |
25 mg 100 mg 250 mg |
$200.00
$300.00 $400.00 |
7 |
| |
Diethylamine NONOateDiethylamine NONOate is a quick-releasing NO donor and MGMT inhibitor |
372965-00-9 |
sc-202575 sc-202575A sc-202575B sc-202575C |
10 mg 50 mg 100 mg 500 mg |
$31.00
$104.00 $190.00 $860.00 |
1 |
| |
O6-BenzylguanineO6-Benzylguanine is an effective substrate and efficient inactivator of DNA alkyltransferase |
19916-73-5 |
sc-202747 sc-202747A |
10 mg 50 mg |
$44.00
$71.00 |
6 |
| |
Mitoxantrone DihydrochlorideMitoxantrone Dihydrochloride is induces DNA damage by intercalating into DNA and inhibiting Topo II |
70476-82-3 |
sc-203136 sc-203136A sc-203136B sc-203136C |
10 mg 50 mg 100 mg 1 g |
$31.00
$57.00 $114.00 $760.00 |
6 |
| |
SinefunginSinefungin is a SAM analog and Dnmt inhibitor |
58944-73-3 |
sc-203263 sc-203263A sc-203263B sc-203263C |
1 mg 10 mg 100 mg 1 g |
$120.00
$615.00 $5,000.00 $38,800.00 |
4 |
| |
Sodium bisulfite, mixture of NaHSO3 and Na2S2O5Sodium bisulfite, mixture of NaHSO3 and Na2S2O5 is an antioxidant and antimicrobial agent for DNA methylation studies |
7631-90-5 |
sc-203273 sc-203273A sc-203273B sc-203273C |
5 g 100 g 500 g 2.5 kg |
$30.00
$35.00 $85.00 $210.00 |
0 |
| |
TemozolomideTemozolomide is an apoptosis inducer which causes arrest at the G2/M cell cycle checkpoint |
85622-93-1 |
sc-203292 sc-203292A |
25 mg 100 mg |
$80.00
$240.00 |
28 |
| |
ZebularineZebularine is an inhibitor of DNA methyltransferase (Dnmt) |
3690-10-6 |
sc-203315 sc-203315A sc-203315B |
10 mg 25 mg 100 mg |
$119.00
$268.00 $960.00 |
3 |
| |
RG 108RG 108 is a Dnmt inhibitor that silences tumor suppressor genes |
48208-26-0 |
sc-204235 sc-204235A |
10 mg 50 mg |
$125.00
$495.00 |
2 |
| |
Chlorogenic AcidChlorogenic Acid is a Bcr-Abl inhibitor |
327-97-9 |
sc-204683 sc-204683A |
500 mg 1 g |
$40.00
$62.00 |
1 |
| |
DisulfiramDisulfiram is an ALDH and tumor cell growth inhibitor |
97-77-8 |
sc-205654 sc-205654A |
50 g 100 g |
$46.00
$80.00 |
6 |
| |
Penicillin G procainePenicillin G procaine is a combination of Penicillin G and Procaine |
6130-64-9 |
sc-205797 sc-205797A |
10 g 25 g |
$46.00
$65.00 |
0 |
| |
1-Hydrazinophthalazine Hydrochloride1-Hydrazinophthalazine Hydrochloride is an inhibitor of Dnmt, MAO-A/B, and amine oxidase |
304-20-1 |
sc-206167 |
10 g |
$280.00
|
0 |
| |
Temozolomide-d3Temozolomide-d3 is a labeled antineoplastic chemical |
208107-14-6 |
sc-212996 |
1 mg |
$300.00
|
0 |
| |
N-Nitroso-N-ethylureaN-Nitroso-N-ethylurea is a precursor of Diazoethane |
759-73-9 |
sc-215469 sc-215469A sc-215469B sc-215469C |
10 g 100 g 500 g 1 kg |
$330.00
$1,600.00 $6,500.00 $9,500.00 |
0 |
| |
R,S-(5′-Adenosyl)-L-methionine p-toluenesulfonate saltR,S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt is a methyl donor and cofactor for enzyme-catalyzed methylations |
52248-03-0 |
sc-215827 sc-215827A sc-215827B |
25 mg 100 mg 500 mg |
$61.00
$124.00 $600.00 |
0 |
| |
3-Methyl-d3-adenine3-Methyl-d3-adenine is an isotope labeled DNA methylater |
5142-23-4 (unlabeled) |
sc-216512 |
1 mg |
$280.00
|
0 |
| |
5-Azacytidine-15N45-Azacytidine-15N4 is a Dnmt inhibitor |
320-67-2 (unlabeled) |
sc-217140 |
1 mg |
$490.00
|
0 |
| |
5-Methylcytosine HCl5-Methylcytosine HCl is Useful in studying DNA methylation |
58366-64-6 |
sc-217223 sc-217223A |
250 mg 1 g |
$101.00
$320.00 |
0 |
| |
5-Azacytidine5-Azacytidine is a potent growth and Dnmt inhibitor |
320-67-2 |
sc-221003 |
500 mg |
$270.00
|
3 |
| |
Procaine hydrochlorideProcaine hydrochloride is a sodium channel blocker and DNA methylation inhibitor |
51-05-8 |
sc-250776 |
250 mg |
$61.00
|
0 |
| |
Psammaplin APsammaplin A is a DNA methyltransferase inhibitor |
110659-91-1 |
sc-258049 sc-258049A |
1 mg 5 mg |
$80.00
$400.00 |
7 |
| |
ProcaineProcaine is a sodium channel blocker and inhibitor of a variety of processes |
59-46-1 |
sc-296134 sc-296134A sc-296134B sc-296134C |
25 g 50 g 500 g 1 kg |
$101.00
$180.00 $386.00 $599.00 |
1 |
| |
LomeguatribLomeguatrib is a monosaccharide-linked inhibitor of MGMT |
192441-08-0 |
sc-362764 sc-362764A |
10 mg 50 mg |
$205.00
$865.00 |
0 |
| |
SemustineSemustine is an alkylating agent and interstrand DNA cross linker |
13909-09-6 |
sc-391062 |
100 mg |
$112.00
|
1 |
| |
SGI-1027SGI-1027 is an inhibitor of the DNA methyltransferases |
1020149-73-8 |
sc-473875 |
10 mg |
$165.00
|
0 |
|