DNA Methylation
Santa Cruz Biotechnology now offers a broad range of DNA Methylation products. DNA Methylation products include compounds which can methylate DNA themselves or act as cofactors for enzyme-catalyzed methylation. Additionally, they include activators and inhibitors of DNA methyltransferases, such as Dnmt and MGMT. DNA methyltransferases help maintain genomic stability by repairing damage and helping prevent mismatch errors from occurring. Research has implicated several mutations affecting these enzymes in the growth and development of various cancers. Our popular products such as Streptozotocin (U-9889), Sinefungin, and S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt are typically available for immediate shipment.
indicates a highly recommended product based on customer preference.
| PRODUCT NAME/Application | CAS | Catalog # | QUANTITY | Price | Citations | RATING | |
|---|---|---|---|---|---|---|---|
Streptozotocin (U-9889)An NO donor and DNA methylating agent | 18883-66-4 | sc-200719 sc-200719A | 1 g 5 g | $104.00 $500.00 | 30 |
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5-Aza-2'-DeoxycytidineA Dnmt inhibitor shown to alter gene expression | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $200.00 $300.00 $400.00 | 3 |
| |
Diethylamine NONOateA quick-releasing NO donor and MGMT inhibitor | 372965-00-9 | sc-202575 sc-202575A sc-202575B sc-202575C | 10 mg 50 mg 100 mg 500 mg | $31.00 $104.00 $190.00 $860.00 | 0 |
| |
O6-BenzylguanineAn effective substrate and efficient inactivator of DNA alkyltransferase | 19916-73-5 | sc-202747 sc-202747A | 10 mg 50 mg | $44.00 $71.00 | 1 |
| |
Mitoxantrone DihydrochlorideInduces DNA damage by intercalating into DNA and inhibiting Topo II | 70476-82-3 | sc-203136 sc-203136A | 10 mg 50 mg | $31.00 $57.00 | 4 |
| |
SinefunginA SAM analog and Dnmt inhibitor | 58944-73-3 | sc-203263 sc-203263A sc-203263B sc-203263C | 1 mg 10 mg 100 mg 1 g | $81.00 $499.00 $5,000.00 $38,800.00 | 3 |
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Sodium bisulfite, mixture of NaHSO3 and Na2S2O5An antioxidant and antimicrobial agent for DNA methylation studies | 7631-90-5 | sc-203273 sc-203273A sc-203273B sc-203273C | 5 g 100 g 500 g 2.5 kg | $21.00 $23.00 $65.00 $163.00 | 0 |
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TemozolomideAn apoptosis inducer which causes arrest at the G2/M cell cycle checkpoint | 85622-93-1 | sc-203292 sc-203292A | 25 mg 100 mg | $80.00 $240.00 | 16 |
| |
ZebularineAn inhibitor of DNA methyltransferase (Dnmt) | 3690-10-6 | sc-203315 sc-203315A sc-203315B | 10 mg 25 mg 100 mg | $119.00 $268.00 $960.00 | 2 |
| |
RG 108A Dnmt inhibitor that silences tumor suppressor genes | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $125.00 $495.00 | 0 |
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Chlorogenic AcidA Bcr-Abl inhibitor | 327-97-9 | sc-204683 sc-204683A | 500 mg 1 g | $40.00 $62.00 | 0 |
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DisulfiramAn ALDH and tumor cell growth inhibitor | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $46.00 $80.00 | 1 |
| |
Penicillin G procaineA combination of Penicillin G and Procaine | 6130-64-9 | sc-205797 sc-205797A | 10 g 25 g | $34.00 $50.00 | 0 |
| |
1-Hydrazinophthalazine HydrochlorideAn inhibitor of Dnmt, MAO-A/B, and amine oxidase | 304-20-1 | sc-206167 | 10 g | $240.00 | 0 |
| |
Temozolomide-d3A labeled antineoplastic chemical | 208107-14-6 | sc-212996 | 1 mg | $220.00 | 0 |
| |
N-Nitroso-N-ethylureaA precursor of Diazoethane | 759-73-9 | sc-215469 sc-215469A sc-215469B sc-215469C | 10 g 100 g 500 g 1 kg | $165.00 $1,600.00 $6,500.00 $9,500.00 | 0 |
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R,S-(5'-Adenosyl)-L-methionine p-toluenesulfonate saltA methyl donor and cofactor for enzyme-catalyzed methylations | 52248-03-0 | sc-215827 sc-215827A sc-215827B | 25 mg 100 mg 500 mg | $61.00 $124.00 $600.00 | 0 |
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3-Methyl-d3-adenineAn isotope labeled DNA methylater | 5142-23-4 (unlabeled) | sc-216512 | 1 mg | $200.00 | 0 |
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5-Azacytidine-15N4A Dnmt inhibitor | 320-67-2 (unlabeled) | sc-217140 | 1 mg | $450.00 | 0 |
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5-Methylcytosine HClUseful in studying DNA methylation | 58366-64-6 | sc-217223 sc-217223A | 250 mg 1 g | $101.00 $320.00 | 0 |
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5-AzacytidineA potent growth and Dnmt inhibitor | 320-67-2 | sc-221003 | 500 mg | $190.00 | 2 |
| |
Procaine hydrochlorideA sodium channel blocker and DNA methylation inhibitor | 51-05-8 | sc-250776 | 250 mg | $61.00 | 0 |
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Psammaplin AA DNA methyltransferase inhibitor | 110659-91-1 | sc-258049 sc-258049A | 1 mg 5 mg | $80.00 $400.00 | 5 |
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ProcaineA sodium channel blocker and inhibitor of a variety of processes | 59-46-1 | sc-296134 sc-296134A sc-296134B sc-296134C | 25 g 50 g 500 g 1 kg | $101.00 $180.00 $386.00 $599.00 | 0 |
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LomeguatribA monosaccharide-linked inhibitor of MGMT | 192441-08-0 | sc-362764 sc-362764A | 10 mg 50 mg | $205.00 $865.00 | 0 |
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SemustineAn alkylating agent and interstrand DNA cross linker | 13909-09-6 | sc-391062 | 100 mg | $112.00 | 0 |
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SGI-1027An inhibitor of the DNA methyltransferases | 1020149-73-8 | sc-473875 | 10 mg | $165.00 | 0 |
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