DHRS12, which stands for Dehydrogenase/Reductase 12, is a protein that is encoded by the DHRS12 gene in humans. This protein is a member of the short-chain dehydrogenases/reductases (SDR) family, which is a large group of enzymes that exhibit oxidoreductase activity, typically with NAD or NADP as cofactors.
The exact biological function of DHRS12 remains not fully characterized, but proteins in the SDR family generally play crucial roles in metabolism, including the catalysis of reactions involving the dehydrogenation of substrates and the reduction of aldehydes and ketones. These enzymes are involved in a wide array of physiological processes, such as the metabolism of steroids, prostaglandins, and xenobiotics, as well as in the synthesis of lipids, hormones, and vitamins.DHRS12, like other members of the SDR family, is likely to be involved in metabolic pathways within cells. Its expression patterns and enzymatic activities may contribute to cellular homeostasis and the regulation of redox states, which are vital for maintaining a balance between the production of reactive oxygen species and the cell's antioxidant defenses.
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