Histone deacetylase proteins (HDACs) are a class of enzymes that remove acetyl groups (O=C-CH3) from an <ε>-N-acetyl lysine amino acid on a histone, allowing histones to wrap DNA more tightly. The deacetylation of histones is associated with transcriptional silencing. HDAC Substrates are used in the quantification and identification of HDAC activity. HDAC Substrates offered by Santa Cruz affects HDAC and, in some cases, other chromatin remodeling and transcription regulation related proteins. View detailed HDAC Substrate specifications, including HDAC Substrate CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
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