p53 Inhibitors

Santa Cruz Biotechnology now offers a broad range of p53 Inhibitors. p53 is a DNA-binding tumor suppressor, which upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation and cell cycle control mechanisms. p53 Inhibitors offered by Santa Cruz inhibit p53 and, in some cases, other cell death and cell differentiation related proteins. View detailed p53 Inhibitor specifications, including p53 Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
Ellipticine
Ellipticine is a DNA intercalating inhibitor of Topo II
519-23-3 sc-200878
sc-200878A
10 mg
50 mg
$104.00
$430.00
4
(1)
Nutlin-3
Nutlin-3is an apoptosis inducer and disruptor of MDM2-p53 interaction, inhibiting with a IC50 of 0.09 µM.
548472-68-0 sc-45061
sc-45061A
sc-45061B
1 mg
5 mg
25 mg
$45.00
$197.00
$739.00
16
(1)
Pifithrin-alpha hydrobromide
Pifithrin-α hydrobromide is an inhibitor of p53 that reversibly blocks p53 dependent transcriptional activation and apoptosis
63208-82-2 sc-45050
sc-45050A
5 mg
25 mg
$106.00
$272.00
30
(1)
Roscovitine
Roscovitine is a potent and selective inhibitor of cyclin-dependent kinases. Selective for Cdk1, Cdk2, and Cdk5
186692-46-6 sc-24002
sc-24002A
1 mg
5 mg
$37.00
$105.00
28
(2)
Pifithrin-alpha, p-Nitro
Pifithrin-α, p-Nitro is a cell-permeable p53 inhibitor
389850-21-9 sc-222176
5 mg
$125.00
2
(2)
Pifithrin-mu
Pifithrin-µ is an inhibitor of p53 activity and HSP 70 activity
64984-31-2 sc-203195
sc-203195A
10 mg
50 mg
$120.00
$360.00
4
(1)
9-Hydroxyellipticine, Hydrochloride
9-Hydroxyellipticine, Hydrochloride is a potent topoisomerase II inhibitor
52238-35-4 sc-203940
sc-203940A
10 mg
50 mg
$220.00
$700.00
0
(1)
Pifithrin-α, p-nitro, cyclic
Pifithrin-α, p-nitro, cyclic is A cell-permeable p53 inhibitor that is more potent & longer half-life than Pifithrin-α
60477-38-5 sc-222177
sc-222177A
sc-222177B
sc-222177C
5 mg
10 mg
25 mg
50 mg
$164.00
$300.00
$600.00
$1,100.00
0
(1)
Cyclic Pifithrin-alpha hydrobromide
Cyclic Pifithrin-α hydrobromide is a cyclic analog of pifithrin-α
511296-88-1 sc-361164
sc-361164A
10 mg
50 mg
$222.00
$915.00
1
(0)
SJ 172550
SJ 172550 is a MDMX inhibitor that inhibits MDMX-p53 interaction in cultured cells
431979-47-4 sc-357403
sc-357403A
10 mg
50 mg
$169.00
$709.00
0
(1)
(+)-Nutlin-3
(+)-Nutlin-3 is a potent inhibitor of p53-Mdm2 interaction
675576-97-3 sc-222085
sc-222085A
500 µg
1 mg
$90.00
$118.00
0
(0)
(-)-Nutlin-3
(–)-Nutlin-3 is an inhibitor of p-53-MDM2 interaction
675576-98-4 sc-222086
sc-222086A
1 mg
5 mg
$113.00
$203.00
2
(1)

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