PPAR alpha Inhibitors

Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors activated by a variety of compounds. PPARs promote transcription by forming heterodimers with members of the retinoid X receptor (RXR) family of steroid receptors and binding to specific DNA motifs termed PPAR-response elements (PPREs). PPARα is abundant in primary hepatocytes, where it regulates the expression of proteins involved in fatty acid metabolism. PPAR alpha Inhibitors offered by Santa Cruz inhibit PPAR alpha and, in some cases, other nuclear hormone receptor and transcription regulation related proteins. View detailed PPAR alpha Inhibitor specifications, including PPAR alpha Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
MK-886 sodium salt
MK-886 sodium salt is a potent and selective inhibitor of FLAP and Cox-1
118427-55-7 sc-200608B
1 mg
5 mg
25 mg
GW6471 is a complete inhibitor of PPARα that allows interaction with co-repressors
436159-64-7 sc-300779
5 mg

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