Cox-2 Inhibitors

Santa Cruz Biotechnology now offers a broad range of Cox-2 Inhibitors. Cyclooxygenase-2 (Prostaglandin endoperoxide H synthase, Cox-2) converts arachidonic acid (AA) to prostaglandin endoperoxide H2. Cox-2 is efficiently induced in migratory cells responding to pro-inflammatory stimuli and is considered to be an important mediator of inflammation. The expression of Cox-2 is upregulated in many cancers, and inhibiting Cox-2 may be relavent in the prevention and treatment of certain types of cancer. Cox-2 Inhibitors offered by Santa Cruz inhibit Cox-2 and, in some cases, other prostaglandin and inflammation related proteins. View detailed Cox-2 Inhibitor specifications, including Cox-2 Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
SB 203580
SB 203580 is a pyridinyl imidazole and specific inhibitor that suppresses p38 mediated activation of MK2.
152121-47-6 sc-3533
sc-3533A
1 mg
5 mg
$84.00
$332.00
226
(5)
(R)-Ibuprofen
(R)-Ibuprofen is an inhibitor of Cox-1 and Cox-2
51146-57-7 sc-200625
200 mg
$126.00
3
(1)
Bromfenac Sodium
120638-55-3 sc-337599
100 mg
$560.00
0
(0)
Chelerythrine chloride
Chelerythrine chloride is a potent and selective inhibitor of protein kinase C
3895-92-9 sc-3547
sc-3547A
5 mg
25 mg
$81.00
$300.00
16
(1)
Diclofenac Sodium
Diclofenac Sodium is an inhibitor of Cox-1 and Cox-2
15307-79-6 sc-202136
sc-202136A
5 g
25 g
$28.00
$116.00
0
(1)
A77 1726
A77 1726 is an active metabolite of leflunomide that inhibits Cox-2
163451-81-8 sc-207235
10 mg
$55.00
11
(1)
Curcumin (Synthetic)
Curcumin (Synthetic) is reported to suppress COX-1, COX-2, NF-κB and other inflammatory mediators
458-37-7 sc-294110
sc-294110A
5 g
25 g
$50.00
$150.00
2
(1)
Acetaminophen
Acetaminophen is a Cox-1, Cox-2, and Cox-3 (cyclooxygenase) inhibitor
103-90-2 sc-203425
sc-203425A
sc-203425B
5 g
100 g
500 g
$20.00
$25.00
$114.00
3
(1)
Radicicol
Radicicol is a potent inhibitor of HSP 90, SRC, and Cox-2
12772-57-5 sc-200620
sc-200620A
1 mg
5 mg
$80.00
$320.00
13
(1)
Aspirin
Aspirin is an inhibitor of COX-1 (cylooxygenase) and NFκB
50-78-2 sc-202471
sc-202471A
5 g
50 g
$20.00
$40.00
3
(1)
Ebselen
Ebselen is a cysteine modifier that inhibits 5-LO, 15-LO, Cox, NADPH, and NADPH oxidase
60940-34-3 sc-200740B
sc-200740
sc-200740A
1 mg
25 mg
100 mg
$20.00
$125.00
$435.00
4
(1)
Indomethacin
Indomethacin is an inhibitor of Cox-1 and activator of PPARγ
53-86-1 sc-200503
sc-200503A
1 g
5 g
$23.00
$31.00
7
(1)
Sedanolide
Sedanolide is an inducer of GST and inhibitor of Cox-1, Cox-2, Topo I, Topo II, and carcinogenesis
6415-59-4 sc-205972
100 mg
$148.00
0
(1)
Xanthorrhizol
Xanthorrhizol is a pro-apoptotic inhibitor of Cox-2 and NOS2
30199-26-9 sc-202855
1 mg
$150.00
1
(1)
Zaltoprofen
Zaltoprofen is an inhibitor of Cox-1 and Cox-2
74711-43-6 sc-213173
sc-213173A
10 mg
100 mg
$130.00
$290.00
1
(1)
NS-398
NS-398 is a selective Cox-2 inhibitor neuroprotective agent
123653-11-2 sc-200604
sc-200604A
5 mg
25 mg
$82.00
$325.00
5
(1)
Carprofen
Carprofen is an antiinflammatory inhibitor of COX-2
53716-49-7 sc-205621
sc-205621A
1 g
5 g
$74.00
$349.00
0
(1)
Curcumin
Curcumin is a yellow-orange dye, NOS2 regulator, and inhibitor of NF-κB, 5-LO, Cox-2, COP9, and p300/CBP.
458-37-7 sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$19.00
$38.00
$60.00
$110.00
$220.00
$835.00
$1,920.00
16
(1)
Robenacoxib
Robenacoxib is a COX-2 selective inhibitor
220991-32-2 sc-391707
100 mg
$180.00
0
(0)
Niflumic acid
Niflumic acid is a selective Cox-2 inhibitor and GPR35 activator
4394-00-7 sc-204820
5 g
$30.00
2
(1)
9-cis-Retinoic acid
9-cis-Retinoic acid is a Cox-2 inhibitor that prevents cell proliferation and induces cell differentiation
5300-03-8 sc-205589
sc-205589A
sc-205589B
sc-205589C
sc-205589D
1 mg
5 mg
25 mg
250 mg
500 mg
$64.00
$135.00
$400.00
$3,000.00
$5,500.00
3
(1)
(S)-Ibuprofen
(S)-Ibuprofen is an inhibitor of Cox-1 and Cox-2
51146-56-6 sc-200612
sc-200612A
1 g
5 g
$41.00
$132.00
2
(1)
Sulindac sulfide
Sulindac sulfide is an active metabolite of sulindac that inhibits for Cox
32004-67-4 sc-200118
sc-200118A
5 mg
25 mg
$61.00
$215.00
2
(1)
Leflunomide
Leflunomide is an inhibitor of Cox-2 and tyrosine kinase
75706-12-6 sc-202209
sc-202209A
10 mg
50 mg
$20.00
$79.00
3
(1)
Tenidap
Tenidap is a 5-LO and selective Cox-1 inhibitor
120210-48-2 sc-204334
sc-204334A
10 mg
50 mg
$129.00
$548.00
1
(1)
(S)-(+)-Flurbiprofen
(S)-(+)-Flurbiprofen is an inhibitor of Cox-1 and Cox-2
51543-39-6 sc-205503
sc-205503A
sc-205503B
sc-205503C
10 mg
50 mg
1 g
1.5 g
$25.00
$113.00
$1,000.00
$1,800.00
0
(0)
Meclofenamate sodium
Meclofenamate sodium is an inhibitor of 5-LO, Cox-1, and Cox-2
6385-02-0 sc-200532
sc-200532A
1 g
5 g
$50.00
$75.00
0
(0)
Sulindac
Sulindac is an inhibitor of the NF-κB pathway and a Cox inhibitor
38194-50-2 sc-202823
sc-202823A
sc-202823B
1 g
5 g
10 g
$30.00
$82.00
$144.00
2
(1)
4′-Hydroxy Diclofenac
4′-Hydroxy Diclofenac is a Cox-2 inhibitor and an active CYP2C9 metabolite of the NSAID diclofenac.
64118-84-9 sc-202423
sc-202423A
1 mg
5 mg
$167.00
$600.00
2
(0)
Celecoxib Carboxylic Acid
Celecoxib Carboxylic Acid is a metabolite of the Cox-2 inhibitor celecoxib
170571-01-4 sc-207408
10 mg
$188.00
0
(0)
Inotilone
Inotilone is a potent Cox-2 inhibitor
906366-79-8 sc-207758
5 mg
$124.00
0
(0)
Meloxicam sodium salt
Meloxicam sodium salt is a Cox-2 inhibitor
71125-39-8 sc-215294
100 mg
$177.00
1
(0)
Isoxicam
Isoxicam is a nonsteroidal anti-inflammatory
34552-84-6 sc-235433
1 g
$77.00
0
(0)
Acetylsalicylic Acid-d4
Acetylsalicylic Acid-d4 is an inhibitor of Cox-1 and Cox-2
97781-16-3 sc-217570
5 mg
$280.00
1
(1)
Sodium Salicylate
Sodium Salicylate is an NF kappa B inhibitor and reducer of oxidative stress
54-21-7 sc-3520
sc-3520A
sc-3520B
sc-3520C
1 g
25 g
500 g
1 kg
$5.00
$20.00
$74.00
$128.00
6
(1)
Rutaecarpine
Rutaecarpine is an inhibitor of Cox-2 and platelet aggregation
84-26-4 sc-205846
sc-205846A
10 mg
25 mg
$123.00
$359.00
1
(0)
Deguelin
Deguelin is an inhibitor of Cox-2
522-17-8 sc-200657
sc-200657A
sc-200657B
5 mg
25 mg
500 mg
$67.00
$268.00
$1,821.00
3
(1)
Pterostilbene, Pterocarpus marsupium
Pterostilbene, Pterocarpus marsupium is a Cox-1 and Cox-2 inhibitor
537-42-8 sc-203223
10 mg
$203.00
0
(0)
Berberine hydrochloride
Berberine hydrochloride is an isoquinoline alkaloid
633-65-8 sc-204645
sc-204645A
sc-204645B
sc-204645C
sc-204645D
1 g
5 g
25 g
100 g
500 g
$20.00
$45.00
$120.00
$360.00
$1,270.00
3
(1)
Indomethacin Methyl Ester
Indomethacin Methyl Ester is a selective COX-2 inhibitor
1601-18-9 sc-207757
10 mg
$220.00
0
(0)
N-tert-Butyl-a-phenylnitrone
N-tert-Butyl-a-phenylnitrone is a Cox-2 inhibitor
3376-24-7 sc-202722
500 mg
$50.00
0
(1)
Flurbiprofen
Flurbiprofen is a potent inhibitor of Cox-1 and Cox-2
5104-49-4 sc-202158
sc-202158A
100 mg
1 g
$68.00
$102.00
0
(1)
Tryptanthrin
Tryptanthrin is a potent inhibitor of Cox-2 and NOS II
13220-57-0 sc-202844
sc-202844A
1 mg
5 mg
$50.00
$213.00
0
(0)
Tolfenamic Acid
Tolfenamic Acid is a non steroidal anti-inflammatory agent found to inhibit COX-2 isoenzymes
13710-19-5 sc-204918
sc-204918A
5 g
25 g
$68.00
$306.00
0
(1)
Ibuprofen
Ibuprofen is a Cox-1 and Cox-2 inhibitor
1189866-35-0 (unlabeled) sc-200534
sc-200534A
1 g
5 g
$44.00
$78.00
2
(0)
Ketoprofen
Ketoprofen is an inhibitor of Cox-1 and Cox-2
22071-15-4 sc-205359
sc-205359A
5 g
25 g
$86.00
$297.00
1
(0)
(S)-Ketoprofen
(S)-Ketoprofen is an inhibitor of TXB2 generation and of Cox
22161-81-5 sc-200624
1 g
$114.00
0
(1)
Naproxen
Naproxen is a Cox-1 and Cox-2 inhibitor
22204-53-1 sc-200506
sc-200506A
1 g
5 g
$24.00
$39.00
0
(1)
6-Methoxy-2-Naphthylacetic acid
6-Methoxy-2-Naphthylacetic acid is a competitive and selective inhibitor of Cox-2
23981-47-7 sc-200602
sc-200602A
10 mg
50 mg
$82.00
$325.00
4
(0)
Naproxen Sodium Salt
Naproxen Sodium Salt is a nonselective inhibitor of Cox-1 and Cox-2
26159-34-2 sc-212361
25 g
$177.00
1
(0)
Piroxicam
Piroxicam is an inhibitor of prostaglandin synthesis as well as Cox-1 and Cox-2
36322-90-4 sc-200576
sc-200576A
1 g
5 g
$44.00
$180.00
2
(0)
Etodolac
Etodolac is a Cox-2 inhibitor with anti-inflammatory activity
41340-25-4 sc-204747
sc-204747A
100 mg
250 mg
$85.00
$125.00
1
(1)
Nimesulide
Nimesulide is a selective Cox-2 inhibitor
51803-78-2 sc-200623
5 g
$71.00
0
(0)
Ethyl 3,4-Dihydroxycinnamate
A Cox-2, iNOS, NOS II, and PGE2 inhibitor
66648-50-8 sc-205930
sc-205930A
25 mg
250 mg
$51.00
$360.00
0
(0)
Loxoprofen
Loxoprofen is a non-steroidal anti-inflammatory compound
68767-14-6 sc-221861
5 mg
$300.00
0
(0)
Lornoxicam
Lornoxicam is a cyclooxygenase inhibitor
70374-39-9 sc-207833
sc-207833A
10 mg
100 mg
$40.00
$93.00
0
(1)
Meloxicam
Meloxicam is an inhibitor of Cox-1 and Cox-2, selective for Cox-2
71125-38-7 sc-200626
sc-200626A
sc-200626B
20 mg
100 mg
500 mg
$34.00
$90.00
$150.00
2
(1)
Ketorolac
Ketorolac is a heterocyclic acetic acid derivative that inhibits prostaglandins
74103-06-3 sc-279250
500 mg
$500.00
0
(0)
Ketorolac (tromethamine salt)
Ketorolac (tromethamine salt) is a non selective inhibitior of Cox-1 and Cox-2
74103-07-4 sc-205360
sc-205360A
500 mg
1 g
$20.00
$50.00
3
(0)
Nepafenac
Nepafenac is an analgesic selective inhibitor of COX-2
78281-72-8 sc-208091
10 mg
$240.00
0
(0)
Cinnamtannin B-1
Cinnamtannin B-1 is a potent antioxidant and Cox-2 inhibitor
88082-60-4 sc-202997
5 mg
$237.00
0
(1)
DuP-697
DuP-697 is a thiophene that inhibits Cox-2
88149-94-4 sc-200680
sc-200680A
5 mg
25 mg
$114.00
$465.00
0
(1)
Aceclofenac
Aceclofenac is an anti-inflammatory and analgesic agent
89796-99-6 sc-217557
10 mg
$58.00
0
(0)
Pravadoline
Pravadoline is a cannabimimetic analgesic and Cox-1 and Cox-2 inhibitor
92623-83-1 sc-200369
sc-200369A
5 mg
25 mg
$47.00
$251.00
0
(0)
COX-2 Inhibitor V, FK3311
COX-2 Inhibitor V, FK3311 is a selective Cox-2 inhibitor and NSAID
116686-15-8 sc-202557
5 mg
$199.00
0
(0)
rac Ibuprofen-d3
rac Ibuprofen-d3 is a selective cyclooxygenase inhibitor
121662-14-4 sc-208276
10 mg
$280.00
0
(0)
Fexofenadine HCl
Fexofenadine HCl is an antihistamine that inhibits Cox-1, Cox-2, and is a histamine H1 receptor agonist
153439-40-8 sc-203047
sc-203047A
10 mg
50 mg
$95.00
$399.00
0
(0)
Licofelone
Licofelone is an inhibitor of Cox-1, Cox-2, and 5-lipoxygenase
156897-06-2 sc-207826
sc-207826A
sc-207826B
sc-207826C
5 mg
250 mg
1 g
4 g
$60.00
$240.00
$800.00
$3,200.00
3
(1)
Vioxx
Vioxx is a selective Cox-2 inhibitorthat has anti-inflammatory properties
162011-90-7 sc-208486
100 mg
$146.00
3
(1)
SC236
SC236 is a highly selective and potent inhibitor of Cox-2 and Cox-1
170569-86-5 sc-222298
sc-222298A
5 mg
25 mg
$77.00
$304.00
0
(0)
COX-2 Inhibitor II
COX-2 Inhibitor II is a selective inhibitor of Cox-2
181696-33-3 sc-221437
5 mg
$270.00
0
(0)
Etoricoxib
Etoricoxib is a specific inhibitor of COX-2
202409-33-4 sc-218446
10 mg
$35.00
0
(1)
Lumaricoxib
Lumaricoxib is a Cox-2 selective inhibitor and NSAID
220991-20-8 sc-205736
sc-205736A
100 mg
250 mg
$140.00
$280.00
0
(0)
Indomethacin Ester, 4-Methoxyphenyl-
Indomethacin Ester, 4-Methoxyphenyl- is a potent and selective inhibitor of COX-2
261766-24-9 sc-221757
5 mg
$340.00
0
(0)
N-(2-Phenylethyl)indomethacin Amide
N-(2-Phenylethyl)indomethacin Amide is an inhibitor of Cox-2
261766-32-9 sc-218925
50 mg
$250.00
0
(0)
COX-1 Inhibitor II
COX-1 Inhibitor II is a selective inhibitor of Cox-1
304913-22-2 sc-202556
25 mg
$195.00
0
(0)
3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole
3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole is a dual inhibitor of Cox-2 and 5-L
443919-96-8 sc-205108
sc-205108A
1 mg
5 mg
$90.00
$406.00
0
(0)
2,4,5-Trimethoxybenzaldehyde
2,4,5-Trimethoxybenzaldehyde is a selective Cox-2 inhibitor
4460-86-0 sc-238357
sc-238357A
25 g
100 g
$51.00
$177.00
0
(0)
CAY10404
CAY10404 is a selective inhibitors of COX-2
340267-36-9 sc-223860
sc-223860A
1 mg
5 mg
$36.00
$162.00
1
(0)
FR122047 monohydrate
FR122047 monohydrate is a highly selective Cox-1 inhibitor
sc-221628
sc-221628A
sc-221628B
sc-221628C
1 mg
5 mg
10 mg
50 mg
$25.00
$95.00
$168.00
$739.00
0
(0)
Indomethacin heptyl ester
Indomethacin heptyl ester is a selective Cox-2 inhibitor that reduces expression and activity of MDR-1
sc-221758
sc-221758A
1 mg
5 mg
$24.00
$108.00
0
(0)
MEG, Hydrochloride
MEG, Hydrochloride is a NOS2, Cox-1, and Cox-2 inhibitor
19767-44-3 sc-364694
10 mg
$225.00
0
(0)
SC 58125
SC 58125 is a selective Cox-2 inhibitor
162054-19-5 sc-204267
sc-204267A
10 mg
50 mg
$113.00
$550.00
0
(0)
APHS
APHS is a anti-inflammatory, selective, and potent Cox-2 inhibitor
209125-28-0 sc-200668
sc-200668B
10 mg
100 mg
$250.00
$2,000.00
0
(0)
N-(3-Pyridyl)indomethacin Amide
N-(3-Pyridyl)indomethacin Amide is a potent and selective reversible Cox-2 inhibitor
261755-29-4 sc-218939
50 mg
$250.00
0
(0)
N-(4-Acetamidophenyl)indomethacin Amide
N-(4-Acetamidophenyl)indomethacin Amide is a selective reversible Cox-2 inhibitor
261766-23-8 sc-207912
50 mg
$250.00
0
(0)
NO-Indomethacin
NO-Indomethacin is a Cox-1 and Cox-2 inhibitor and NO donor
301838-28-8 sc-205414
sc-205414A
sc-205414B
sc-205414C
1 mg
5 mg
10 mg
50 mg
$25.00
$108.00
$192.00
$849.00
0
(0)
COX-2 Inhibitor I
COX-2 Inhibitor I is an inhibitor of Cox-2
416901-58-1 sc-221436
5 mg
$257.00
0
(0)
YS121
YS121 is an inhibitor of mPGES-1, 5-LO, Cox-1, and Cox-2
916482-17-2 sc-296707
sc-296707A
1 mg
5 mg
$56.00
$251.00
0
(0)
ZLJ-6
ZLJ-6 is an inhibitor of Cox-1, Cox-2, and 5-LO
1051931-39-5 sc-224468
sc-224468A
1 mg
5 mg
$40.00
$180.00
0
(0)
CAY10589
CAY10589 is an inhibitor of 5-LO, Cox-1, and Cox-2
1077626-52-8 sc-223872
sc-223872A
1 mg
5 mg
$56.00
$255.00
0
(0)
TCS PIM-1 4a
TCS PIM-1 4a is a selective and ATP-competitive Pim kinase inhibitor
438190-29-5 sc-296450
sc-296450A
10 mg
50 mg
$63.00
$339.00
0
(0)
N-(3-hydroxyphenyl)-Arachidonoyl amide
N-(3-hydroxyphenyl)-Arachidonoyl amide is a selective, irreversible inhibitor of COX-2
183718-75-4 sc-221969
sc-221969A
5 mg
10 mg
$40.00
$76.00
0
(0)
Diclofenac diethylamine
Diclofenac diethylamine is An anti-inflammatory drug that is an inhibitor of leukocyte migration and the enzyme cyclooxygenase (COX-1 and COX-2)
78213-16-8 sc-357333
sc-357333A
5 g
25 g
$120.00
$233.00
0
(0)
Indomethacin sodium
Indomethacin sodium is a Cox-1 and Cox-2 inhibitor
7681-54-1 sc-337874
1 g
$560.00
0
(0)
Bromfenac monosodium salt sesquihydrate
120638-55-3 (anhydrous) sc-358075
sc-358075A
25 mg
100 mg
$141.00
$494.00
0
(0)
(S)-Ketorolac
(S)-Ketorolac is a prostaglandin biosynthesis inhibitor
66635-92-5 sc-208368
5 mg
$350.00
0
(0)
Wogonin, S. baicalensis
Wogonin, S. baicalensis is a flavonoid that displays anti-inflammatory properties
632-85-9 sc-203313
10 mg
$200.00
11
(1)
Wogonin
Wogonin is an anti-inflammatory agent and inhibitor of COX-2
632-85-9 sc-216062
sc-216062A
5 mg
25 mg
$144.00
$560.00
0
(0)
7-(Trifluoromethyl)1H-indole-2,3-dione
391-12-8 sc-217411
100 mg
$250.00
0
(0)
Ampiroxicam
Ampiroxicam is a COX-1 and COX-2 inhibitor
99464-64-9 sc-210813
10 mg
$147.00
0
(0)
(S)-(+)-Ketoprofen
(S)-(+)-Ketoprofen is a Cox inhibitor
22161-81-5 sc-212844
100 mg
$83.00
0
(0)
(S)-(+)-Ibuprofen (S)-(+)-Lysinate
(S)-(+)-Ibuprofen (S)-(+)-Lysinate is a non-steroidal anti-inflammatory drug
sc-220042
25 mg
$240.00
0
(0)
Meloxicam-d3
Meloxicam-d3 is an anti-inflammatory
sc-218687
1 mg
$280.00
0
(0)
Firocoxib
Firocoxib is a selective cyclooxygenase-2 (Cox-2) inhibitor
189954-96-9 sc-470944
1 mg
$180.00
0
(0)
DFU
CAS: 178402-36-3, MF: C19H17FO4S, MW: 360.4
178402-36-3 sc-489951
5 mg
$61.00
0
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