NOS Activators

Nitric oxide (NO) has a broad range of biological activities including cell signaling pathways in phylogenetically diverse species. Nitric oxide synthases (NOSs), the enzymes responsible for synthesis of NO, contain an N-terminal oxygenase domain and a C-terminal reductase domain. NOS activity requires homodimerization as well as three cosubstrates (L-arginine, NADPH and O2) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin and heme). NOS Activators offered by Santa Cruz activate NOS and, in some cases, other cell signaling and nitric oxide synthesis related proteins. View detailed NOS Activator specifications, including NOS Activator CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
DAF-FM
DAF-FM is a photo-stable nitric oxide (NO) fluorescent indicator with a detection limit of ~3 nM
254109-20-1 sc-396104
1 mg
$785.00
0
(0)
Histamine, free base
Histamine, free base is a compound that activates NOS which results in the release of NO
51-45-6 sc-204000
sc-204000A
sc-204000B
1 g
5 g
25 g
$90.00
$272.00
$950.00
4
(1)
Tetrahydrobiopterin (THB) dihydrochloride
Tetrahydrobiopterin (THB) dihydrochloride is an activating NOS cofactor
69056-38-8 sc-200345
sc-200345A
25 mg
100 mg
$79.00
$196.00
10
(1)
Hyperforin dicyclohexylammonium salt
Hyperforin dicyclohexylammonium salt is an inhibitor of monoamine uptake and TRPC6 agonsit
238074-03-8 sc-202178
sc-202178A
500 µg
1 mg
$134.00
$176.00
1
(1)
PTIO
PTIO is a nitric oxide (NO) radical scavenger used to inhibit physiological effects of NO
18390-00-6 sc-202782
sc-202782A
25 mg
100 mg
$37.00
$110.00
4
(1)
7,8-Dihydro-L-biopterin
7,8-Dihydro-L-biopterin is a precursor of BH4 synthesis
6779-87-9 sc-202895
sc-202895A
10 mg
50 mg
$95.00
$300.00
1
(1)
Prostaglandin G2
Prostaglandin G2 is the first intermediary in the COX pathway which is stable enough to be isolated and characterized
51982-36-6 sc-205471
sc-205471A
25 µg
50 µg
$96.00
$184.00
0
(0)
Agmatine sulfate
Agmatine sulfate is an L-arginine decarboxy analog with neurotransmiter activity
2482-00-0 sc-202920
sc-202920A
100 mg
500 mg
$69.00
$178.00
0
(0)
Ethylthiourea
Ethylthiourea is a bactericidal precursor
625-53-6 sc-203333
10 g
$132.00
0
(0)
Gemfibrozil
Gemfibrozil is a hyperlipidemic agent
25812-30-0 sc-204764
sc-204764A
5 g
25 g
$64.00
$257.00
1
(2)
L-Biopterin
L-Biopterin is a cofactor in the production of many neurotransmitters and nitric oxide
22150-76-1 sc-204781
sc-204781A
25 mg
100 mg
$90.00
$210.00
1
(1)
Isatin
Isatin is an endogenous monoamine oxidase inhibitor
91-56-5 sc-205721
sc-205721A
100 g
500 g
$63.00
$276.00
0
(0)
Calmodulin (human), (recombinant)
Calmodulin (human), (recombinant) is an activator of NOS, PDE and CaMK
73298-54-1 sc-471287
1 mg
$222.00
0
(0)
Oleanolic Acid
Oleanolic Acid is a compound useful for the induction of iNOS and of Cyclooxygenase 2
508-02-1 sc-205775
sc-205775A
100 mg
500 mg
$77.00
$285.00
3
(2)
Penicillamine
Penicillamine is an exogenous NOS modulator and an antirheumatic and chelating agent used for Wilson′s disease
52-67-5 sc-205795
sc-205795A
1 g
5 g
$28.00
$92.00
0
(0)
4-Chloro-3-methylpyridine 1-Oxide
1073-34-3 sc-206857
10 mg
$250.00
0
(0)
4-Phenyl-3-furoxancarbonitrile
4-Phenyl-3-furoxancarbonitrile is an soluble guanylate cyclase activator
125520-62-9 sc-206935
10 mg
$96.00
0
(0)
2,3-Diaminonaphthalene
2,3-Diaminonaphthalene is an inhibitor of nitric oxide formation
771-97-1 sc-202882
100 mg
$60.00
0
(0)
Diphenyleneiodonium Sulfate
Diphenyleneiodonium Sulfate is a downstream inhibitor of NO synthase, NADG reductase and NADPH oxidase
4510-83-2 sc-207583
50 mg
$210.00
3
(0)
Hydroxyurea-15N
214331-53-0 sc-207747
1 mg
$220.00
0
(0)
S-Ethyl N-[4-Triflurormethyl)phenyl]isothiourea, Hydrochloride
163490-78-6 sc-208325
10 mg
$220.00
0
(0)
S-Ethyl N-Phenylisothiourea
S-Ethyl N-Phenylisothiourea is A potent inhibitor of the human neuronal, constitutive, and inducible isoforms of NOS.
19801-34-4 sc-208326
50 mg
$250.00
0
(0)
tert-Butyl N-[3-(Acetimidoylaminomethyl)benzyl]carbamate, Hydrochloride
tert-Butyl N-[3-(Acetimidoylaminomethyl)benzyl]carbamate, Hydrochloride is A human iNOS inhibitor and intermediate for a selective iNOS inhibitor.
180001-98-3 sc-208426
5 mg
$150.00
0
(0)
N-Methyl-L-aspartic acid
4226-18-0 sc-212234
sc-212234A
10 mg
50 mg
$19.00
$50.00
0
(0)
N-Nitroso Akardite II
1076199-26-2 sc-219204
250 mg
$220.00
0
(0)
2-Imino-4-methylpiperidine, Acetate
sc-216215
10 mg
$220.00
0
(0)
2-Imino-4,6-dimethylpiperidine, Acetate
2-Imino-4,6-dimethylpiperidine, Acetate is a strong inhibitor of human NOS2 (iNOS)
165383-79-9 sc-216216
10 mg
$220.00
0
(0)
2-Methyl-3,4-dichloropyridine N-Oxide
sc-216247
250 mg
$250.00
0
(0)
4-Methyl-1-hydrazinophthalizine Hydrochloride
29902-28-1 (non-salt) sc-216923
10 mg
$200.00
0
(0)
5-Acetoxymethyl-2,3-dimethyl-4-chloropyridine N-oxide
sc-217113
10 mg
$152.00
0
(0)
S-Nitroso-N-valeryl-D,L-penicillamine
S-Nitroso-N-valeryl-D,L-penicillamine is can exhibit high lipophilicity and stability in solution
225233-99-8 sc-220025
25 mg
$210.00
0
(1)
5-Acetoxymethyl-2,3-dimethylpyridine N-oxide
sc-217115
25 mg
$280.00
0
(0)
Glyco-SNAP-2
Glyco-SNAP-2 is a highly soluble nitric oxide donor
188849-82-3 sc-218911
sc-218911A
10 mg
50 mg
$150.00
$750.00
0
(0)
N-(Indole)nitroso Naratriptan
sc-218969
1 mg
$280.00
0
(0)
N-(Methyl-d3)-Nprime-nitrosopiperazine
sc-218973
25 mg
$250.00
0
(0)
N,N-Dicarboxymethyl-N,N-dinitroso-p-phenylenediamine, Disodium Salt
N,N-Dicarboxymethyl-N,N-dinitroso-p-phenylenediamine, Disodium Salt is a caged, photolabile Nitric Oxide donor
1042969-16-3 sc-219273
sc-219273A
1 mg
5 mg
$280.00
$1,300.00
0
(0)
N4-tert-Butoxycarbonyl-1-[2-(2-hydroxyethoxy)ethyl]piperazine N1-Oxide
N4-tert-Butoxycarbonyl-1-[2-(2-hydroxyethoxy)ethyl]piperazine N1-Oxide is an intermediate in Quetiapine derivative preparation
sc-219313
250 mg
$240.00
0
(0)
Nicotinic Acid Methyl Ester 5-N-Methylnitrone
Nicotinic Acid Methyl Ester 5-N-Methylnitrone is a nicotinic acid derivative for proteomics research
sc-219366
100 mg
$220.00
0
(0)
Ropinirole N-Oxide
Ropinirole N-Oxide is a reference standard
1076199-41-1 sc-219988
1 mg
$280.00
0
(0)
S-Nitroso-N-heptanoyl-D,L-penicillamine
225234-00-4 sc-220023
10 mg
$240.00
0
(0)
S-Nitroso-N-propionyl-D,L-penicillamine
225233-98-7 sc-220024
10 mg
$240.00
3
(0)
alpha-Carboline-15N2 N-Oxide
sc-220428
1 mg
$300.00
0
(0)
BEC, Hydrochloride
BEC, Hydrochloride is a competitive transition state inhibitor of arginases I and II
sc-221291
5 mg
$345.00
0
(0)
Carboxy-PTIO, Sodium Salt
Carboxy-PTIO, Sodium Salt is a SIN-1 induced endothelial cell death inhibitor
148819-93-6 (non-salt) sc-221395
10 mg
$171.00
0
(0)
DAR-4M
DAR-4M is a rhodamine-based photo-stable NO fluorescent indicator
sc-221529
1 mg
$562.00
0
(0)
DAR-4M AM
DAR-4M AM is a cell-permeable photo-stable nitric oxide fluorescent indicator with a detection limit of ~10 nM.
sc-221530
1 mg
$700.00
3
(1)
Diethylamine NONOate/AM
Diethylamine NONOate/AM is an intracellular nitric oxide donor
213768-16-2 sc-221540
sc-221540A
1 mg
5 mg
$218.00
$667.00
0
(0)
FeTPPS
FeTPPS is a decomposition catalyst and a selective peroxynitrite scavenge
90384-82-0 sc-221611
sc-221611A
250 mg
1 g
$195.00
$600.00
2
(1)
Glyco-SNAP-1
Glyco-SNAP-1 is a water-soluble nitric oxide donor
188849-81-2 sc-221680
sc-221680A
5 mg
25 mg
$260.00
$650.00
1
(1)
Hypoestoxide, Hypoestes rosea
Hypoestoxide, Hypoestes rosea is a naturally occurring, cell-permeable diterpene
88498-46-8 sc-221735
1 mg
$208.00
0
(0)
L-Thiocitrulline
CAS: 156719-37-8, MF: C6H13N3O2S, MW: 191.25, Purity: >98%
156719-37-8 sc-221813
sc-221813A
10 mg
50 mg
$57.00
$216.00
0
(0)
Lipopolysaccharide, E. coli J5
Lipopolysaccharide, E. coli J5 is an E. coli mutant that stimulates the activity of inducible NO synthase
sc-221854
5 mg
$119.00
1
(0)
Lipopolysaccharide, E. coli 055:B5
Lipopolysaccharide, E. coli O55:B5 is a component of the cell wall of Gram-negative bacteria and Specific activator of Toll-like receptor (TLR) 4.
sc-221855
sc-221855A
sc-221855B
sc-221855C
10 mg
25 mg
100 mg
500 mg
$70.00
$125.00
$310.00
$1,125.00
7
(2)
Lipopolysaccharide, Re 595
Lipopolysaccharide, Re 595 is a strain that stimulates the activity of NOS2 and induces apoptosis
sc-221856
5 mg
$225.00
0
(1)
Lipopolysaccharide, Ultra Pure, Salmonella minnesota R595 (Re)
Lipopolysaccharide, Ultra Pure, Salmonella minnesota R595 (Re) is a phenol-petroleum ether
sc-221858
1 mg
$350.00
0
(0)
MnTBAP chloride
MnTBAP chloride is a cell permeable superoxide dismutase mimetic and peroxynitrite reactive oxygen species (ROS) scavenger.
55266-18-7 sc-221954
sc-221954A
10 mg
50 mg
$33.00
$90.00
32
(1)
NG-Hydroxy-L-arginine, Monoacetate Salt
NG-Hydroxy-L-arginine, Monoacetate Salt is an intermediate in the biosynthesis of nitric oxide
53598-01-9 sc-222067
sc-222067A
25 mg
5 mg
$327.00
$83.00
0
(0)
NG-Monomethyl-L-homoarginine monoacetate
NG-Monomethyl-L-homoarginine monoacetate is NG-Monomethyl-L-homoarginine monoacetate is an inhibitor of NOS.
sc-222069
5 mg
$50.00
0
(0)
ROS Probe, HPF
ROS Probe, HPF is a cell-permeable, photo-stable hydroxyphenyl-substituted fluorescein compound
359010-69-8 sc-222262
1 mg
$520.00
0
(0)
L-N6-(1-Iminoethyl) Lysine 5-Tetrazole Amide, Dihydrochloride
MF: C9H22Cl2N8O, MW: 329.23
sc-280886
5 mg
$220.00
0
(0)
Lansoprazole-d4 Sulfone N-Oxide
Lansoprazole-d4 Sulfone N-Oxide is a labeled impurity of Lansoprazole
sc-280903
1 mg
$450.00
0
(0)
BAY-41-8543
CAS: 256498-66-5, MF: C21H21FN8O, MW: 420.4
256498-66-5 sc-291927
sc-291927A
1 mg
5 mg
$77.00
$605.00
0
(0)
4-Amino-(6R)-5,6,7,8-tetrahydro-L-biopterin dihydrochloride
sc-362202
10 mg
$1,000.00
0
(0)

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