Gene Regulation Reagents

Santa Cruz Biotechnology now offers a broad range of Gene Regulation Reagents. Gene Regulation Reagents are compounds that affect the expression of genes and their products through a variety of mechanisms, including the up- or down- regulation of gene expression via the activation or inhibition of transcription factors. Our popular products such as Hypoxia Inducible Factor-1α Inhibitor, Mitomycin C, and Dimethyloxaloylglycine (DMOG) are typically available for immediate shipment.

indicates a highly recommended product based on customer preference.

PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
Hygromycin B solution
An antibiotic often used for selection of cells transfected with E. coli hygromycin resistance gene.
31282-04-9 sc-29067
sc-29067A
sc-29067B
1 g
5 g
10 g
$95.00
$415.00
$829.00
25
(4)
MC 1568
A class II (IIa) HDAC inhibitor selective for HDAC4 and HDAC6
852475-26-4 sc-362767
sc-362767A
10 mg
50 mg
$175.00
$555.00
4
(1)
Hypoxia inducible factor-1α inhibitor Inhibitor
Hypoxia inducible factor-1α inhibitor is an HIF and HIF-1α inhibitor which suppresses expression of downstream target genes
934593-90-5 sc-205346
sc-205346A
sc-205346B
sc-205346C
1 mg
5 mg
10 mg
25 mg
$22.00
$100.00
$176.00
$385.00
15
(1)
Mitomycin C
A DNA crosslinking agent that inhibits DNA synthesis, induces apoptosis in a variety of cells, and activates caspase
50-07-7 sc-3514
sc-3514A
sc-3514B
5 mg
2 mg
10 mg
$87.00
$50.00
$125.00
44
(4)
BAY 11-7082
BAY 11-7082 is an anti-inflammatory agent and NFκB inhibitor
19542-67-7 sc-200615
sc-200615A
sc-200615B
10 mg
50 mg
5 mg
$81.00
$342.00
$60.00
102
(1)
Actinomycin D
A potent antibiotic that binds to the GpC steps of DNA
50-76-0 sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$62.00
$224.00
$693.00
$2,462.00
$20,990.00
23
(3)
Dimethyloxaloylglycine (DMOG)
An inhibitor of PHF and FIH-1 that upregulates HIF-1α and FLRG
89464-63-1 sc-200755
sc-200755A
sc-200755B
sc-200755C
10 mg
50 mg
100 mg
500 mg
$70.00
$279.00
$350.00
$739.00
15
(2)
Bufalin
Inducer of apoptosis in human HL-60 and U-937 cell lines
465-21-4 sc-200136
sc-200136A
sc-200136B
sc-200136C
10 mg
25 mg
50 mg
100 mg
$97.00
$200.00
$334.00
$533.00
4
(1)
Mithramycin A
A polymerase inhibitor that binds to GC rich sequences located in the minor groove of DNA
18378-89-7 sc-200909
1 mg
$53.00
4
(1)
Rifampicin
An antibiotic that potently inhibits RNA polymerase and is an activator of PXR
13292-46-1 sc-200910
sc-200910A
sc-200910B
sc-200910C
1 g
5 g
100 g
250 g
$83.00
$306.00
$640.00
$1,400.00
4
(1)
AG 1024
Inhibits insulin-stimulated cellular proliferation and IGF-1R autophosphorylation
65678-07-1 sc-205907
1 mg
$82.00
16
(1)
GW 3965 hydrochloride
A liver X receptor (LXR) activator
405911-17-3 sc-224011
sc-224011A
5 mg
25 mg
$134.00
$465.00
0
(1)
Smoothened Agonist, HCl
A Hh pathway agonist that interacts with the heptahelical domain of Smo
364590-63-6 sc-202814
sc-202814A
1 mg
5 mg
$200.00
$500.00
29
(1)
N-3-oxo-dodecanoyl-L-Homoserine lactone
An activator of transcription factors NF-κB and AP-2
168982-69-2 sc-205399
sc-205399A
1 mg
5 mg
$31.00
$139.00
0
(1)
7-Aminoactinomycin D
A fluorescent DNA dye for apoptosis and flow cytomtery studies
7240-37-1 sc-221210
sc-221210A
1 mg
5 mg
$167.00
$390.00
7
(2)
5prime-Deoxy-5prime-methylthioadenosine
An endogenous methylthioadenosine phosphorylase substrate and potent inhibitor of PDE
2457-80-9 sc-202427
50 mg
$89.00
0
(1)
RG 108
A Dnmt inhibitor that silences tumor suppressor genes
48208-26-0 sc-204235
sc-204235A
10 mg
50 mg
$125.00
$495.00
0
(1)
C646
A selective p300, CBP, histone H3 and H4 inhibitor
328968-36-1 sc-364452
sc-364452A
10 mg
50 mg
$199.00
$902.00
5
(1)
BADGE
An inhibitor of PPARγ and suppressor of TNFα
1675-54-3 sc-202487
sc-202487A
sc-202487B
sc-202487C
25 g
50 g
100 g
500 g
$32.00
$44.00
$57.00
$180.00
1
(1)
N-3-oxo-octanoyl-L-Homoserine lactone
A reagent that promotes the expression of the transcriptional activator
147795-39-9 sc-205400
sc-205400A
5 mg
10 mg
$46.00
$88.00
0
(0)
5-Aza-2'-Deoxycytidine
A Dnmt inhibitor shown to alter gene expression
2353-33-5 sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$200.00
$300.00
$400.00
3
(1)
alpha-Sarcin
A ribosome-inactivating protein and apoptosis inducer
86243-64-3 sc-204427
1 mg
$300.00
2
(0)
5-Fluoroorotic acid monohydrate
A gene regulation reagent for proteomics research
220141-70-8 sc-217188
1 g
$75.00
0
(1)
RNA Polymerase III Inhibitor
An indazolo-sulfonamide compound displaying inhibitory activity against RNA Polymerase III
577784-91-9 sc-222257
10 mg
$390.00
0
(1)
GSK J1
A selective and potent inhibitor of JMJDE and UTX demethylases
1373422-53-7 sc-391113
sc-391113A
10 mg
50 mg
$185.00
$781.00
0
(0)
VAHA
An inhibitor to HDAC with efficacy against Class I and II enzymes
106132-78-9 sc-364642
sc-364642A
5 mg
25 mg
$64.00
$341.00
0
(0)
Histone Lysine Methyltransferase Inhibitor
Histone Lysine Methyltransferase Inhibitor is an HMTase inhibitor known as BIX-01294 Trihydrochloride
935693-62-2 (hydrate) sc-202651
5 mg
$145.00
3
(1)
AMI-1, free acid
A chemical shown to inhibit arginine, in vitro, with no inhibitory effect on lysine
134-47-4 sc-300192
1 g
$96.00
0
(0)
NFkappaB Activation Inhibitor III
A TNF-α-stimulated NF kappa B activation inhibitor
380623-76-7 sc-204818
5 mg
$99.00
2
(1)
5-Azacytidine
A potent growth and Dnmt inhibitor
320-67-2 sc-221003
500 mg
$190.00
2
(1)
13-cis-Retinoic acid
A vitamin A analog that inhibits cell proliferation
4759-48-2 sc-205568
sc-205568A
100 mg
250 mg
$67.00
$110.00
7
(1)
Bisbenzimide H 33258 Fluorochrome, Trihydrochloride
An A-T specific highly fluorescent DNA stain that has many uses
23491-45-4 sc-202503
sc-202503A
sc-202503B
100 mg
250 mg
1 g
$118.00
$251.00
$493.00
5
(1)
3-Deazaneplanocin, HCl salt
An effective S-adenosylhomocysteine hydrolase inhibitor
120964-45-6 sc-351856
sc-351856A
sc-351856B
1 mg
5 mg
10 mg
$150.00
$400.00
$700.00
2
(1)
Dodecanoyl-L-homoserine lactone
A modulator of cell communication and regulation
137173-46-7 sc-391777
5 mg
$47.00
0
(0)
N-hexanoyl-L-Homoserine lactone
A small diffusible signaling molecule
147852-83-3 sc-205405
sc-205405A
sc-205405B
sc-205405C
5 mg
10 mg
25 mg
50 mg
$50.00
$76.00
$162.00
$313.00
1
(0)
Thyroid Hormone Receptor Antagonist, 1-850
Thyroid Hormone Receptor Antagonist, 1-850 is a selective and high-affinity thyroid hormone receptor (TR) antagonist
251310-57-3 sc-222357A
sc-222357
sc-222357B
1 mg
5 mg
10 mg
$74.00
$92.00
$126.00
2
(1)
N-nonanoyl-L-Homoserine lactone
A rare odd-numbered acyl carbon chain produced by the wild-type Erwinia carotovora strain
177158-21-3 sc-224145
sc-224145A
5 mg
10 mg
$39.00
$74.00
0
(0)
Lycorine hydrochloride
A protein synthesis inhibitor
2188-68-3 sc-200917
sc-200917A
10 mg
50 mg
$75.00
$299.00
0
(1)
BML-266
A SIRT2 inhibitor
96969-83-4 sc-221371
sc-221371A
10 mg
50 mg
$102.00
$402.00
1
(1)
BML-210
An inhibitor of HDAC activity and gene expression modulator
537034-17-6 sc-221369
sc-221369A
1 mg
5 mg
$77.00
$263.00
0
(0)
Triphenyl Compound A
A pirin inhibitor
21306-65-0 sc-364144
sc-364144A
1 mg
5 mg
$47.00
$101.00
0
(0)
beta-Rubromycin
A quinone antibiotic agent that inhibits reverse transcriptase
27267-70-5 sc-204636
sc-204636A
1 mg
5 mg
$177.00
$712.00
0
(0)
AK-7
A deacetylase which targets α-tubulin, histone 4, forkhead transcription factors, and several other substrates it is also a selective SIRT2 inhibitor
420831-40-9 sc-364096
sc-364096A
5 mg
25 mg
$54.00
$221.00
0
(0)
Pimelic Diphenylamide 106
An HDAC1, HDAC2, HDAC3, and HDAC8 inhibitor
937039-45-7 sc-364589
sc-364589A
1 mg
5 mg
$41.00
$74.00
0
(0)
LXRalpha/beta Agonist
A specific liver X receptor (LXR) dual agonist
264206-85-1 sc-221864
10 mg
$315.00
0
(1)
Toxin A from Clostridium difficile
A high molecular weight, small molecule GTPase inhibitor
sc-222361
sc-222361A
2 µg
100 µg
$192.00
$772.00
0
(1)
Linoleic Acid
A fatty acid with cytotoxic activity that influences the inflammatory process
60-33-3 sc-200788
sc-200788A
sc-200788B
sc-200788C
100 mg
1 g
5 g
25 g
$23.00
$52.00
$150.00
$260.00
3
(1)
Oleylethanolamide
An activator of Neu/ErbB2 receptors and a mediator of p38 and JNK kinases
111-58-0 sc-201400
sc-201400A
10 mg
50 mg
$55.00
$164.00
0
(1)
Betamethasone
A glucocorticoid that induces gene expression and apoptosis
378-44-9 sc-204647
sc-204647A
100 mg
500 mg
$160.00
$555.00
0
(1)
Chromomycin A3
A G-C specific DNA ligand which inhibits transcription and acts as a DNA binding dye
7059-24-7 sc-200907
10 mg
$240.00
0
(1)
Hoechst 33342 trihydrochloride
An A:T-specific DNA minor groove ligand used for visualizing cellular DNA
23491-52-3 sc-200908
100 mg
$131.00
5
(1)
3,5-Diiodo-L-thyronine
An iodinated thyronine hormone that regulates activity
1041-01-6 sc-216601
sc-216601A
sc-216601B
sc-216601C
1 g
5 g
10 g
25 g
$220.00
$500.00
$902.00
$1,353.00
0
(0)
Procysteine
A precursor in glutathione synthesis
19771-63-2 sc-200811
1 g
$90.00
0
(0)
O6-Benzylguanine
An effective substrate and efficient inactivator of DNA alkyltransferase
19916-73-5 sc-202747
sc-202747A
10 mg
50 mg
$44.00
$71.00
1
(1)
beta-Amanitin
A specific and potent inhibitor of eukaryotic RNA polymerase II and a mild inhibitor of RNA polymerase III
21150-22-1 sc-202860
1 mg
$195.00
0
(0)
(+)-cis,trans-Abscisic acid
A natural and active isomer of the abscission accelerating plant hormone.
21293-29-8 sc-202103
sc-202103A
500 µg
1 mg
$98.00
$179.00
0
(0)
CB 1954
A compound for gene therapyt resrearch
21919-05-1 sc-214672
sc-214672A
sc-214672B
sc-214672C
sc-214672D
50 mg
100 mg
1 g
5 g
10 g
$215.00
$430.00
$4,212.00
$13,500.00
$24,000.00
1
(1)
Berninamycin A
An antibiotic that contains sulfur and highly modified cyclic peptides
58798-97-3 sc-202077
sc-202077A
1 mg
5 mg
$250.00
$1,014.00
0
(1)
N-butyryl-L-Homoserine lactone
A diffusable quorum sensing lactone
67605-85-0 sc-205402
sc-205402A
5 mg
10 mg
$28.00
$54.00
0
(0)
Leptomycin B, Free Acid
A potent nuclear export and RNA translation inhibitor
87081-35-4 sc-202210
sc-202210A
100 µg
500 µg
$170.00
$670.00
10
(0)
Blasticidin A
An aflatoxin production inhibitor
100513-53-9 sc-202082
1 mg
$500.00
1
(0)
Pioglitazone
A PPAR agonist with potential antidiabetic characteristics
111025-46-8 sc-202289
sc-202289A
1 mg
5 mg
$48.00
$116.00
9
(1)
B2
A cell permeable inhibitor of SIRT2 (sirtuin 2)
115687-05-3 sc-202486
sc-202486A
sc-202486B
500 µg
5 mg
25 mg
$30.00
$150.00
$667.00
0
(0)
Rosiglitazone
A potent and selective PPARγ agonist
122320-73-4 sc-202795
sc-202795A
sc-202795B
25 mg
100 mg
5 g
$106.00
$304.00
$1,200.00
22
(1)
Strontium Ranelate
A bone metabolism modulator
135459-87-9 sc-208403
10 mg
$280.00
0
(0)
N-(beta-ketocaproyl)-L-Homoserine lactone
A component of quorum regulatory sensing
143537-62-6 sc-205396
sc-205396A
5 mg
25 mg
$46.00
$156.00
0
(1)
Dihydromyristicin
An inducer of glutathione S-transferase
52811-28-6 sc-202580
100 mg
$142.00
0
(0)
N-octanoyl-L-Homoserine lactone
A small signaling molecule involved in quorum sensing
147852-84-4 sc-222011
sc-222011A
sc-222011B
sc-222011C
5 mg
10 mg
25 mg
50 mg
$60.00
$89.00
$210.00
$372.00
0
(0)
Geninthiocin
A thiopeptide antibiotic tipA gene activator
158792-27-9 sc-202167
500 µg
$359.00
1
(0)
Levofloxacin hydrochloride
A fluoroquinolone antibiotic inhibitor of DNA gyrase and topoisomerase IV
177325-13-2 sc-202693
sc-202693A
1 g
5 g
$50.00
$95.00
1
(1)
GW 1929
A potent, tyrosine-based PPARγ
196808-24-9 sc-202640
1 mg
$87.00
0
(0)
AG-041R
A potent gastrin/CCKB receptor antagonist that exhibits selective binding for CCKB compared to CCKA
199800-49-2 sc-205202
sc-205202A
1 mg
5 mg
$72.00
$325.00
0
(0)
N-butyryl-L-Homocysteine thiolactone
A small signaling molecule involved in quorum sensing
202284-85-3 sc-221995
sc-221995A
5 mg
10 mg
$39.00
$101.00
0
(0)
M 344
A potent HDAC inhibitor with IC50 of 100 nM
251456-60-7 sc-203124
sc-203124A
1 mg
5 mg
$99.00
$304.00
8
(1)
10074-G5
An inhibitor of c-Myc-Max interaction
413611-93-5 sc-213578
sc-213578B
sc-213578A
sc-213578C
sc-213578D
5 mg
10 mg
25 mg
100 mg
1 g
$82.00
$154.00
$330.00
$982.00
$2,045.00
0
(1)
EGFR Inhibitor
A highly selective, cell-permeable EGFR inhibitor
879127-07-8 sc-203934
1 mg
$99.00
0
(1)
Neurodazine
An inducer of neurogenesis of non-pluripotent C2C12 myoblasts
937807-66-4 sc-222056
10 mg
$145.00
0
(0)
1,2,3,4,5,6,7,8-Octahydro-naphthalene
A quorum sensing agent
493-03-8 sc-396633
sc-396633A
1 g
5 g
$100.00
$350.00
0
(0)
Rifampin, gamma irradiated
13292-46-1 sc-296271
150 mg
$43.00
0
(0)
A1120
sc-300151
25 mg
$313.00
0
(0)
BePl
A biochemical which selectively intercalates into triple-helical DNA
sc-319856
1 mg
$61.00
0
(0)
2-Benzylaminoethanol
Used in the synthesis of imidazoles as potent calcitonin antagonists
104-63-2 sc-229954
100 g
$27.00
0
(0)
4-(3,4-Dimethoxyphenyl)butyric acid
Has effects on apoptosis, proliferation and HDAC activity
13575-74-1 sc-226371
5 g
$54.00
0
(0)
5,6-Dichloropyridine-3-methanol
A novel CXCR3 (CXC chemokine receptor) inhibitor
54127-30-9 sc-278346
200 mg
$90.00
0
(0)
2-Heptyl-3-hydroxyl-4-quinolone
An intercellular signal
108985-27-9 sc-396649
25 mg
$165.00
0
(0)
DIF-1
A cell growth suppressor that promotes differentiation in HL-60 cells
111050-72-7 sc-221541
sc-221541A
100 µg
500 µg
$64.00
$255.00
0
(0)
tert-butyl 2-aminophenylcarbamate
An intermediate in the synthesis of histone deacetylase agents and antitumor agents
146651-75-4 sc-356014
sc-356014A
250 mg
1 g
$188.00
$380.00
0
(0)
LED209
A potent conserved membrane histidine sensor kinase
245342-14-7 sc-205368
sc-205368A
1 mg
5 mg
$18.00
$75.00
0
(0)
Fmoc-L-Lys(Me2)-OH*HCl
A Lysine derivative used to study histone modification
252049-10-8 sc-294919
100 mg
$300.00
0
(0)
CASIN
A Cdc42 GTPase inhibitor
425399-05-9 sc-397016
10 mg
$214.00
0
(0)
N-3-oxo-hexadec-11Z-enoyl-L-Homoserine lactone
An autoinducer
479050-91-4 sc-221977
sc-221977A
1 mg
5 mg
$47.00
$156.00
0
(0)
N-3-oxo-tetradec-7Z-enoyl-L-Homoserine lactone
An antimicrobial agent that inhibits biofilm formation
482598-46-9 sc-205401
sc-205401A
1 mg
5 mg
$28.00
$126.00
0
(0)
Staurosporine Solution in Ethyl Acetate
An ATP-competitive protein kinase inhibitor
62996-74-1 sc-360258
100 µg
$92.00
4
(2)
UNC 0224
A potent G9a histone lysine methyltransferase (HMTase) inhibitor
1197196-48-7 sc-362816
sc-362816A
10 mg
50 mg
$190.00
$800.00
0
(0)
I-BET 151 Hydrochloride
A BET bromodomain (BRD) inhibitor
1300031-49-5 (non HCl Salt) sc-391115
10 mg
$410.00
1
(0)
UNC 926 hydrochloride
A methyl lysine reader domain inhibitor
1184136-10-4 sc-397061
10 mg
$159.00
0
(0)
L-Ascorbic acid 2-phosphate sesquimagnesium salt
A compound used in biocatalytic dephosphorylation, cell differentiation, and tissue engineering research
113170-55-1 sc-228390
sc-228390A
sc-228390B
sc-228390C
5 g
25 g
100 g
500 g
$57.00
$240.00
$500.00
$880.00
3
(1)
Dimethyl fumarate
An ester used for research purposes
624-49-7 sc-239774
25 g
$26.00
4
(1)
Phytic acid dipotassium salt
A potent chelator of divalent and trivalent cations
129832-03-7 sc-253276
sc-253276A
5 g
25 g
$215.00
$454.00
0
(1)
Lys-Tyr-Lys acetate salt
35193-18-1 sc-300944
50 mg
$125.00
0
(0)
GW6471
A complete inhibitor of PPARα that allows interaction with co-repressors
436159-64-7 sc-300779
5 mg
$203.00
6
(1)
N-decanoyl-L-Homoserine lactone
A small signaling molecule involved in quorum sensing
177315-87-6 sc-222001
sc-222001A
sc-222001B
sc-222001C
5 mg
10 mg
25 mg
50 mg
$60.00
$114.00
$237.00
$395.00
0
(0)
N-tridecanoyl-L-Homserine lactone
A bacteria-produced lactone involved in quorum sensing
878627-21-5 sc-204812
sc-204812A
5 mg
10 mg
$39.00
$101.00
0
(0)
13(S)-HODE-d4
Intended for use as an internal quantification standard
139408-39-2 sc-205006
sc-205006A
25 µg
100 µg
$112.00
$405.00
0
(0)
RETRA
CAS: 1036069-26-7, MF: C11H12ClNO3S2, MW: 305.80, Purity: ≥98%
1036069-26-7 sc-311522
5 mg
$115.00
0
(0)
2-Phospho-L-ascorbic acid trisodium salt
A long-lasting vitamin C derivative used in studies of gene repression
66170-10-3 sc-230644
sc-230644A
10 g
25 g
$61.00
$150.00
0
(1)
2-Bromohexadecanoic acid
A PPARδ agonist
18263-25-7 sc-251714
sc-251714A
10 g
50 g
$38.00
$152.00
1
(1)
Pyroxamide
An HDAC1 inhibitor
382180-17-8 sc-397030
5 mg
$79.00
0
(0)
5-Carboxy-8-hydroxyquinoline
5-Carboxy-8-hydroxyquinoline is a histone demethylase JMJD inhibitor
5852-78-8 sc-397023
5 mg
$86.00
0
(0)
LG 100754
An agonist of RXR:PPARγ that enhances ligand binding activity
180713-37-5 sc-361231
sc-361231A
10 mg
50 mg
$142.00
$825.00
0
(1)
Imipenem Monohydrate
A third generation cephalosporin and β-lactam antibiotic
64221-86-9 sc-205350A
sc-205350
5 mg
25 mg
$55.00
$110.00
3
(1)
9-cis-Retinoic acid
A Cox-2 inhibitor that prevents cell proliferation and induces cell differentiation
5300-03-8 sc-205589
sc-205589A
sc-205589B
1 mg
5 mg
25 mg
$64.00
$135.00
$400.00
3
(1)
N-(Ketocaproyl)-L-homoserine Lactone
An autoinducer of P. fischeri luciferase
143537-62-6 sc-207922
100 mg
$213.00
0
(1)
Leptomycin B
A potent and specific nuclear export inhibitor that acts as an antifungal agent
87081-35-4 sc-358688
sc-358688A
sc-358688B
50 µg
500 µg
2.5 mg
$98.00
$400.00
$1,200.00
17
(2)
WDR5-0103
A small molecule inhibitor of WDR5
890190-22-4 sc-397024
5 mg
$72.00
0
(0)
SID 7969543
A selective SF-1 inhibitor
868224-64-0 sc-204278
sc-204278A
10 mg
50 mg
$139.00
$585.00
0
(0)
SAG
A potent agonist of Hedgehog (Hh) signalling
912545-86-9 sc-212905
sc-212905A
1 mg
5 mg
$150.00
$395.00
15
(1)
Cardionogen 1
An inhibitor of Wnt/β-catenin-dependent transcription
577696-37-8 sc-397033
sc-397033A
5 mg
25 mg
$109.00
$399.00
0
(0)
(+/-)-JQ1
A selective BET inhibitor that inhibits Brd4
1268524-69-1 sc-472932
sc-472932A
5 mg
25 mg
$165.00
$638.00
0
(0)
ZLN005
49671-76-3 sc-474381A
sc-474381
sc-474381B
sc-474381C
5 mg
10 mg
25 mg
50 mg
$43.00
$65.00
$153.00
$252.00
0
(0)
OAC-1
An Oct-4 activator which increases mRNA expression of Oct-4, Sox-2, Nanog, and Tet1
300586-90-7 sc-397046
sc-397046A
5 mg
25 mg
$80.00
$339.00
0
(0)

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