Homobifunctional Crosslinkers

Santa Cruz Biotechnology now offers a broad range of Homobifunctional Crosslinkers. Homobifunctional Crosslinkers contain two identical reactive functional groups that are separated at various lengths. The reactive ends are chosen for their particular chemoselective properties, often targeting the primary amines and sulfhydryl groups of proteins. Our popular products such as Dimethyl pimelimidate dihydrochloride, Suberic acid bis(N-hydroxysuccinimide ester), and Disuccinimidyl glutarate are typically available for immediate shipment.

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PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
DIDS, Disodium Salt
DIDS, Disodium Salt is an anion transport inhibitor that inhibits Cl- uptake through plasma membrane-localized Cl- channels.
67483-13-0 sc-203919A
sc-203919B
sc-203919
sc-203919C
25 mg
100 mg
250 mg
1 g
$39.00
$120.00
$170.00
$364.00
3
(1)
1,14-Diazido-3,6,9,12-tetraoxatetradecane
182760-73-2 sc-206217
250 mg
$300.00
0
(0)
3,3prime-Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester
3,3′-Dithiobispropionic Acid Bis-sulfosuccinimidyl Ester is a water soluble and cleavable amine-reactive crosslinker
81069-02-5 sc-206694
100 mg
$168.00
0
(0)
1,1-Methanediyl Bismethanethiosulfonate
1,1-Methanediyl Bismethanethiosulfonate is a sulfhydryl cross-linking reagent
22418-52-6 sc-208706
20 mg
$210.00
0
(0)
1,10-Decadiyl Bismethanethiosulfonate
1,10-Decadiyl Bismethanethiosulfonate is a sulfhydryl cross-linking reagent
56-02-0 sc-208713
25 mg
$280.00
0
(1)
1,11-Bis(methanesulfonyloxy)-3,6,9-trioxandecane
55400-73-2 sc-208714
1 g
$240.00
0
(0)
1,11-Bismaleimidotetraethyleneglycol
1,11-Bismaleimidotetraethyleneglycol is a sulfhydryl reactive homobifunctional reagent
86099-06-1 sc-208715
25 mg
$250.00
0
(0)
1,11-Diazido-3,6,9-trioxaundecane
1,11-Diazido-3,6,9-trioxaundecane is an oligoether spacer and linker compound
101187-39-7 sc-208716
1 g
$420.00
0
(0)
1,2-Ethanediyl Bismethanethiosulfonate
1,2-Ethanediyl Bismethanethiosulfonate is a homobifunctional sulfhydryl-reactive crosslinker, 4 atom spacer arm
55-95-8 sc-208746
25 mg
$300.00
0
(1)
1,2-Phenylene-bis-maleimide
1,2-Phenylene-bis-maleimide is a short, sulfhydryl reactive homobifunctional crosslinking reagent in protein crosslinking
13118-04-2 sc-208752
5 g
$160.00
0
(0)
1,3-Propanediyl Bismethanethiosulfonate
1,3-Propanediyl Bismethanethiosulfonate is a sulfhydryl cross-linking reagent
55-96-9 sc-208779
25 mg
$280.00
0
(0)
1,4-Bis-maleimidobutane
1,4-Bis-maleimidobutane is a thiol reactive crosslinking reagent
28537-70-4 sc-208788
10 mg
$225.00
0
(0)
1,4-Butanediyl Bismethanethiosulfonate
1,4-Butanediyl Bismethanethiosulfonate is a sulfhydryl cross-linking reagent
55-99-2 sc-208789
25 mg
$250.00
0
(0)
1,4-Phenylene-bis-maleimide
1,4-Phenylene-bis-maleimide is a short, sulfhydryl reactive, homobifunctional crosslinking reagent
3278-31-7 sc-208795
5 g
$162.00
0
(0)
1,5-Diazido-3-oxapentane
1,5-Diazido-3-oxapentane is A multifunctional, alkylating agent
24345-74-2 sc-208800
1 g
$240.00
0
(0)
1,5-Pentanediyl Bismethanethiosulfonate
56-00-8 sc-208802
25 mg
$280.00
0
(0)
1,6-Hexane-bis-[3-(2-pyridyldithio)propionamide]
359435-46-4 sc-208807
25 mg
$220.00
0
(0)
1,6-Hexanediyl Bismethanethiosulfonate
1,6-Hexanediyl Bismethanethiosulfonate is a homobifunctional sulfhydryl-reactive crosslinker
56-01-9 sc-208808
25 mg
$250.00
0
(0)
1,8-Bis-maleimidotetraethyleneglycol
1,8-Bis-maleimidotetraethyleneglycol is a homobifunctional sulfhydryl-reactive crosslinker
115597-84-7 sc-208810
25 mg
$165.00
0
(0)
1,8-Octadiyl Bismethanethiosulfonate
1,8-Octadiyl Bismethanethiosulfonate is a homobifunctional sulfhydryl-reactive crosslinker
4356-71-2 sc-208815
25 mg
$250.00
0
(0)
3,6-Dioxaoctane-1,8-diyl Bismethanethiosulfonate
3,6-Dioxaoctane-1,8-diyl Bismethanethiosulfonate is a homobifunctional sulfhydryl-reactive crosslinker
212262-04-9 sc-209726
10 mg
$280.00
0
(0)
3,6,9-Trioxaundecane-1,11-diyl-bismethanethiosulfonate
212262-02-7 sc-209728
10 mg
$300.00
0
(0)
3,6,9,12-Tetraoxatetradecane-1,14-diyl-bis-methanethiosulfonate
212262-08-3 sc-209729
10 mg
$300.00
0
(0)
Bis-maleimidomethyl Ether
Bis-maleimidomethyl Ether is a short sulfhydryl reactive homobifunctional crosslinking reagent
15209-14-0 sc-210928
25 mg
$300.00
0
(0)
Bis[2-(succinimidooxycarbonyloxy)ethyl] Sulfone
Bis[2-(succinimidooxycarbonyloxy)ethyl] Sulfone is a homobifunctional amine-reactive crosslinker, 13.0 angstrom spacer arm
57683-72-4 sc-210948
25 mg
$220.00
0
(0)
Disuccinimidyl L-Tartrate
Disuccinimidyl L-Tartrate is a homobifunctional amine-reactive crosslinker
62069-75-4 sc-211361
250 mg
$210.00
0
(0)
Heptaoxatricosanedioic Acid Bis(N-Hydroxysuccinimide) Ester
211746-85-9 sc-211585
25 mg
$280.00
0
(0)
N-Succinimidoxycarbonyl-β-alanine N-Succinimidyl Ester
N-Succinimidoxycarbonyl-β-alanine N-Succinimidyl Ester is A short amino reactive homobifunctional crosslinking reagent
21994-89-8 sc-212275
sc-212275A
sc-212275B
sc-212275C
sc-212275D
25 mg
100 mg
250 mg
1 g
10 g
$68.00
$150.00
$225.00
$1,030.00
$10,000.00
0
(1)
N,N'-Bis[2-(chloroacetamido)ethyl]-N,N'-dimethylrhodamine
N,N′-Bis[2-(chloroacetamido)ethyl]-N,N′-dimethylrhodamine is a homobifunctional crosslinker
1022050-89-0 sc-212321
1 mg
$280.00
0
(0)
(+/-)-trans-1,2-Bis(chloroacetamido)cyclohexane
150576-46-8 sc-213079
250 mg
$220.00
0
(0)
4,4prime-Diisothiocyanatostilbene-2,2prime-disulfonic acid disodium salt
4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt is a negatively charged homobifunctional cross-linking reagent and dye
207233-90-7 sc-214282
sc-214282A
sc-214282B
25 mg
100 mg
250 mg
$41.00
$86.00
$137.00
0
(1)
DTME
DTME is a homobifunctional , thiol-cleavable, sulfhydryl-reactive crosslinker, 13.3 angstrom spacer arm
71865-37-7 sc-214925A
sc-214925
sc-214925B
sc-214925C
sc-214925D
5 mg
10 mg
25 mg
50 mg
100 mg
$150.00
$210.00
$540.00
$1,055.00
$2,000.00
0
(0)
N,Nprime-Ethylenebis(iodoacetamide)
N,N′-Ethylenebis(iodoacetamide) is A homobifunctional sulfhydryl-reactive crosslinker
7250-43-3 sc-215511
100 mg
$300.00
2
(0)
Bis-(2-methanethiosulfonatoethyl)dimethylammonium Chloride
sc-217766
5 mg
$280.00
0
(0)
Decaoxadotriacontadioic Acid Bis(N-Hydroxysuccinimide) Ester
sc-218093
5 mg
$350.00
0
(0)
MTS-17-O5-MTS
MTS-17-O5-MTS is A sulfhydryl cross-linking reagent
384342-61-4 sc-218886
25 mg
$280.00
0
(0)
Nonaoxanonacosanedioic Acid Bis(N-Hydroxysuccinimide) Ester
sc-219394
5 mg
$350.00
0
(0)
Octaoxahexacosanedioic Acid Bis(N-Hydroxysuccinimide) Ester
sc-219459
5 mg
$350.00
0
(0)
Suberate Bis(sulfosuccinimidyl) Sodium Salt
Suberate Bis(sulfosuccinimidyl) Sodium Salt is A water soluble, amine reactive, homobifunctional crosslinker
127634-19-9 sc-220138
100 mg
$255.00
0
(1)
alpha,alphaprime-Paraxylyl Bismethanethiosulfonate
α,α′-Paraxylyl Bismethanethiosulfonate is A sulfhydryl cross-linking reagent
3948-46-7 sc-220450
10 mg
$240.00
0
(0)
O,Oprime-Bis[2-(N-Succinimidyl-succinylamino)ethyl]polyethylene glycol
186020-53-1 sc-228867
1 g
$239.00
0
(0)
PEG NHS ester disulfide (n=7)
PEG NHS ester disulfide (n=7) is commonly used as a linker molecule
947601-98-1 sc-236303
100 mg
$189.00
0
(1)
DPDPB
DPDPB is a thiol-cleavable, homobifunctional sulfhydryl-reactive crosslinker
141647-62-3 sc-237746
10 mg
$128.00
0
(0)
Bis[2-(4-azidosalicylamido)ethyl] disulfide
Bis[2-(4-azidosalicylamido)ethyl] disulfide is A homobifunctional, long chain cross-linking reagent
199804-21-2 sc-239377
10 mg
$265.00
0
(0)
Dimethyl erimidate dihydrochloride
Dimethyl suberimidate dihydrochloride is a homobifunctional imidoester based crosslinker, amine reactive
34490-86-3 sc-239782
5 g
$76.00
0
(0)
p-Phenylene diisothiocyanate
4044-65-9 sc-250628
1 g
$31.00
0
(0)
Dimethyl 3,3prime-dithiopropionimidate dihydrochloride
Dimethyl 3,3′-dithiopropionimidate dihydrochloride is A thiol-cleavable, homobifunctional amine-reactive crosslinker, 8-atom spacer arm
38285-78-8 sc-252733
100 mg
$84.00
0
(0)
Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester)
Ethylene glycol-bis(succinic acid N-hydroxysuccinimide ester) is a homobifunctional, cleavable, amine-reactive crosslinker, 12 atom spacer arm
70539-42-3 sc-252807
sc-252807A
250 mg
1 g
$124.00
$300.00
0
(0)
Sebacic acid bis(N-succinimidyl) ester
Sebacic acid bis(N-succinimidyl) ester is a reagent for crosslinking proteins and peptides
23024-29-5 sc-253546
100 mg
$63.00
0
(0)
Suberic acid bis(N-hydroxysuccinimide ester)
Suberic acid bis(N-hydroxysuccinimide ester) is a homobifunctional amine-reactive crosslinker, 8 atom spacer arm
68528-80-3 sc-253611
sc-253611A
500 mg
1 g
$72.00
$119.00
0
(0)
Adipic acid dihydrazide
CAS: 1071-93-8, MF: C6H14N4O2, MW: 174.20, Purity: ≥99%
1071-93-8 sc-257072
25 g
$63.00
0
(0)
Glutaraldehyde solution, 70% w/w
Glutaraldehyde solution, 70% w/w is A homobifunctional crosslinker suitable as a fixative for electron microscopy
111-30-8 sc-257558
10 ml
$46.00
1
(1)
3,3prime-Dithiodipropionic acid di(N-hydroxysuccinimide ester)
3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) is a cleavable disulfide linkage-containing homobifunctional cross-linking reagent
57757-57-0 sc-266859
500 mg
$140.00
0
(1)
Dimethyl pimelimidate dihydrochloride
A homobifunctional amine-reactive crosslinker
58537-94-3 sc-268943
sc-268943A
250 mg
1 g
$45.00
$60.00
1
(3)
4,4prime-Diisothiocyano-2,2prime-dihydrostilbenedisulfonic Acid Disodium Salt
150321-88-3 sc-281687
250 mg
$250.00
0
(0)
Disuccinimidyl glutarate
Disuccinimidyl glutarate is an amine-reactive, NHS ester-based crosslinker useful in isolation of the insulin receptor.
79642-50-5 sc-285455
sc-285455A
sc-285455B
sc-285455C
sc-285455D
100 mg
500 mg
1 g
5 g
10 g
$136.00
$255.00
$500.00
$2,500.00
$5,000.00
7
(1)
Glutaraldehyde solution, 25% w/w
Glutaraldehyde solution, 25% w/w is a protein cross-linking agent
111-30-8 sc-300764A
sc-300764
sc-300764B
10 ml
100 ml
1 L
$20.00
$35.00
$104.00
1
(1)
Bis(sulphosuccinimidyl)erate
Bis(sulphosuccinimidyl)suberate is a crosslinking agent
87067-99-0 sc-353092
100 mg
$240.00
0
(0)
1,6-Bis-maleimidohexane
1,6-Bis-maleimidohexane is a sulfhydryl reactive maleimide based crosslinker, 16.1 angstrom spacer arm
4856-87-5 sc-357486
100 mg
$194.00
0
(0)
3-Maleimidopropionic Acid Hydrazonium, Trifluoroacetate
CAS: 359436-61-6, MF: C7H9N3O3•C2F3O2, MW: 296.18
359436-61-6 sc-357610
25 mg
$240.00
0
(0)
Ethylene-bis-maleimide
Ethylene-bis-maleimide is a homobifunctional sulfhydryl-reactive crosslinker
5132-30-9 sc-358228
100 mg
$220.00
0
(0)

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