Cell Synchronization Reagents
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Aphidicolin | 38966-21-1 | sc-201535 sc-201535A sc-201535B | 1 mg 5 mg 25 mg | $84.00 $306.00 $1104.00 | 30 | |
Aphidicolin is a selective inhibitor of DNA polymerase, primarily affecting the S phase of the cell cycle. By binding to the enzyme's active site, it disrupts DNA synthesis, leading to cell cycle arrest. This compound's unique ability to interfere with nucleotide incorporation results in a synchronized population of cells, allowing for detailed studies of cellular processes. Its specificity for DNA polymerase makes it a valuable tool for investigating replication dynamics and cell cycle regulation. | ||||||
Acyclovir | 59277-89-3 | sc-202906 sc-202906A | 50 mg 500 mg | $150.00 $940.00 | 2 | |
Acyclovir acts as a potent cell synchronization reagent by selectively inhibiting viral DNA polymerase, which indirectly influences host cell replication processes. Its unique structure allows it to mimic nucleosides, leading to competitive inhibition of nucleotide incorporation during DNA synthesis. This interaction results in a distinct arrest of cells in the S phase, facilitating the study of cellular dynamics and the regulation of the cell cycle without affecting normal cellular functions. | ||||||