ADNP inhibitors represent a specialized class of chemical compounds designed to selectively modulate the activity of activity-dependent neuroprotective protein (ADNP). ADNP is a multifunctional protein that plays a pivotal role in neuronal development, functioning as a transcription factor that regulates the expression of genes crucial for neurogenesis and synaptic plasticity. The inhibitors targeting ADNP act by disrupting its interactions with specific cellular components, hindering its regulatory functions. These chemical entities are meticulously crafted to interact with the active sites of ADNP, thereby interfering with the intricate signaling cascades that govern neuroprotective processes. The development of ADNP inhibitors stems from a profound interest in unraveling the molecular mechanisms underpinning neuronal function and development.
ADNP inhibitors is a result of intricate research aimed at elucidating the binding interfaces and molecular interactions that govern ADNP's role in neuroprotection. By selectively inhibiting ADNP, these compounds provide researchers with invaluable tools to explore the nuanced regulatory networks governing neural processes. The study of ADNP inhibitors contributes to the expanding field of neuropharmacology, shedding light on the molecular underpinnings of neuroprotective mechanisms. As scientists delve deeper into the structural characteristics of ADNP inhibitors, they pave the way for a more comprehensive understanding of the intricate molecular landscape that shapes neuronal development and resilience in the face of various physiological and environmental challenges.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
JQ1 is a potent inhibitor of the bromodomain and extra-terminal (BET) family of proteins, including BRD4. BRD4 has been found to interact with ADNP. Therefore, inhibiting BRD4 may indirectly affect ADNP function. | ||||||
I-BET 151 Hydrochloride | 1300031-49-5 (non HCl Salt) | sc-391115 | 10 mg | $450.00 | 2 | |
I-BET151 is another potent BET inhibitor that can modulate the transcriptional network in which ADNP is involved, potentially indirectly influencing ADNP activity. | ||||||
(S)-2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-hydroxyphenyl)acetamide | 202590-98-5 | sc-501130 | 2.5 mg | $330.00 | ||
(S)-2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-hydroxyphenyl)acetamide is a BET inhibitor that can potentially affect ADNP function indirectly by modulating the transcriptional network in which ADNP is involved. | ||||||