Santa Cruz Biotechnology offers a variety of gene editing products to target specific proteins using the CRISPR/Cas9 system. Provisionally named gene products such as chromosome open reading frame (Corf), KIAA, LOC and TMEM proteins likely play an important role in proper cellular function and are pending further characterization. As an example, KIAA1199 is an uncharacterized protein that may be involved in hearing as it is specifically expressed in the cochlea and vestibular tissues. To knockdown protein expression, Santa Cruz Biotechnology offers target-specific CRISPR/Cas9 Knockout (KO) Plasmids and CRISPR Double Nickase Plasmids.To activate gene transcription, Santa Cruz Biotechnology offers target-specific CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems.