Date published: 2025-9-18

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Acid Halides

Santa Cruz Biotechnology now offers a broad range of Acid Halides for use in various applications. Acid halides, also known as acyl halides, are a class of organic compounds derived from carboxylic acids by replacing the hydroxyl group (-OH) with a halide group (such as chloride, bromide, or fluoride). These compounds are highly reactive intermediates in organic synthesis due to the electrophilic nature of the carbonyl carbon, which readily undergoes nucleophilic acyl substitution reactions. Acid halides are pivotal in the synthesis of a wide array of chemical compounds, including esters, amides, and anhydrides, making them indispensable in chemical research and industrial processes. In scientific research, acid halides are frequently used to study reaction mechanisms and to develop new synthetic methodologies. Their reactivity also allows for the modification of complex molecules, facilitating the construction of elaborate molecular architectures and the introduction of functional groups that can be further manipulated. Additionally, acid halides play a crucial role in polymer chemistry, where they are used to produce polymers with specific structural and functional properties. Researchers have employed acid halides to explore the synthesis of novel materials, catalysts, and ligands, thereby advancing the fields of materials science, catalysis, and coordination chemistry. The availability of a wide variety of acid halides from Santa Cruz Biotechnology enables researchers to select the appropriate compound for their specific needs, thus driving innovation and discovery in multiple scientific disciplines. View detailed information on our available acid halides by clicking on the product name.

Items 301 to 310 of 374 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-bromo-2-butoxybenzoyl chloride

sc-336818
100 mg
$150.00
(0)

5-bromo-2-butoxybenzoyl chloride is a notable acid halide characterized by its aromatic structure and the presence of a bromine atom, which influences its reactivity. The bromine enhances the electrophilicity of the carbonyl, making it a potent acylating agent. This compound can engage in rapid nucleophilic acyl substitution, leading to diverse synthetic pathways. Its butoxy group contributes to solubility and steric effects, further modulating reaction kinetics and selectivity in various chemical transformations.

2-Chloro-5-(trifluoromethyl)benzenesulfonyl chloride

54090-08-3sc-274546
1 g
$94.00
(0)

2-Chloro-5-(trifluoromethyl)benzenesulfonyl chloride is a distinctive acid halide featuring a trifluoromethyl group that significantly enhances its electrophilic character. This compound exhibits strong reactivity towards nucleophiles, facilitating swift acylation reactions. The presence of the sulfonyl chloride moiety allows for unique interactions with amines and alcohols, promoting diverse synthetic routes. Its chlorinated aromatic framework also contributes to its stability and selectivity in various chemical environments.

2-(2,4-dichlorophenoxy)propanoyl chloride

sc-320494
100 mg
$150.00
(0)

2-(2,4-Dichlorophenoxy)propanoyl chloride is a notable acid halide characterized by its dichlorophenoxy group, which imparts enhanced steric hindrance and electronic effects. This compound demonstrates a high reactivity towards nucleophiles, enabling rapid acylation and substitution reactions. The presence of the acid chloride functionality allows for efficient formation of esters and amides, while its unique molecular structure facilitates selective interactions in complex synthetic pathways, making it a versatile intermediate in organic synthesis.

3-chloro-6-methyl-1-benzothiophene-2-carbonyl chloride

sc-335765
100 mg
$200.00
(0)

3-Chloro-6-methyl-1-benzothiophene-2-carbonyl chloride is a distinctive acid halide featuring a benzothiophene core that enhances its reactivity profile. The presence of the chloro and methyl substituents contributes to its electrophilic character, promoting swift acylation reactions with nucleophiles. This compound's unique structure allows for selective interactions in diverse synthetic routes, facilitating the formation of various derivatives while exhibiting notable stability under specific conditions.

2-(4-ethylphenyl)-8-methylquinoline-4-carbonyl chloride

sc-320748
100 mg
$150.00
(0)

2-(4-ethylphenyl)-8-methylquinoline-4-carbonyl chloride is a notable acid halide characterized by its quinoline framework, which imparts unique electronic properties. The presence of the ethyl and methyl groups enhances steric hindrance, influencing reaction kinetics and selectivity during acylation processes. This compound exhibits a propensity for forming stable intermediates, allowing for efficient coupling reactions with various nucleophiles, thus expanding its utility in synthetic chemistry.

2,3,4,5-Tetrachlorobenzoyl Chloride

42221-52-3sc-476510
25 g
$165.00
(0)

2,3,4,5-Tetrachlorobenzoyl Chloride is a distinctive acid halide featuring a highly chlorinated aromatic ring, which significantly enhances its electrophilicity. The multiple chlorine substituents create a strong electron-withdrawing effect, facilitating rapid acylation reactions with nucleophiles. This compound's reactivity is further influenced by its ability to stabilize transition states, leading to efficient formation of acyl derivatives. Its unique structure allows for selective functionalization in complex organic syntheses.

2-(2,4-difluorophenoxy)propanoyl chloride

sc-320504
100 mg
$150.00
(0)

2-(2,4-difluorophenoxy)propanoyl chloride is a notable acid halide characterized by its difluorophenoxy group, which imparts unique steric and electronic properties. The presence of fluorine atoms enhances the compound's electrophilic nature, promoting swift acylation with nucleophiles. Its distinctive molecular interactions enable selective reactivity, making it a versatile intermediate in various synthetic pathways. The compound's ability to stabilize reactive intermediates contributes to its efficiency in forming diverse acyl derivatives.

2-(3-methyl-4-nitrophenoxy)butanoyl chloride

sc-320607
100 mg
$150.00
(0)

2-(3-methyl-4-nitrophenoxy)butanoyl chloride is an intriguing acid halide distinguished by its nitrophenoxy moiety, which introduces significant electron-withdrawing effects. This feature enhances its reactivity towards nucleophiles, facilitating rapid acylation reactions. The compound's unique steric hindrance from the methyl group influences its selectivity in synthetic routes, allowing for tailored synthesis of complex molecules. Its reactivity profile is further characterized by the formation of stable intermediates, promoting efficient transformation in various chemical processes.

4-[(3-bromobenzyl)oxy]benzoyl chloride

sc-336203
100 mg
$150.00
(0)

4-[(3-bromobenzyl)oxy]benzoyl chloride is a notable acid halide characterized by its bromobenzyl ether linkage, which imparts unique electronic properties. The presence of the bromine atom enhances electrophilicity, making it highly reactive towards nucleophiles. This compound exhibits distinct reaction kinetics, often leading to rapid acylation and the formation of diverse acyl derivatives. Its structural features also allow for selective functionalization, enabling the synthesis of complex organic frameworks.

4-(4-Chlorophenoxy)benzenesulfonyl chloride

191327-30-7sc-284026
sc-284026A
100 mg
250 mg
$135.00
$270.00
(0)

4-(4-Chlorophenoxy)benzenesulfonyl chloride is a distinctive acid halide known for its sulfonyl chloride functionality, which enhances its reactivity towards nucleophiles. The chlorophenoxy group contributes to its unique steric and electronic environment, facilitating selective acylation reactions. This compound exhibits rapid reaction kinetics, often leading to the formation of sulfonamide derivatives. Its ability to engage in diverse coupling reactions makes it a versatile intermediate in organic synthesis.