Cox Inhibitors

Santa Cruz Biotechnology now offers a broad range of Cox Inhibitors. Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid (AA). Cox Inhibitors offered by Santa Cruz inhibit Cox and, in some cases, other prostaglandin and inflammation related proteins. View detailed Cox Inhibitor specifications, including Cox Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
Sulindac sulfide
Sulindac sulfide is an active metabolite of sulindac that inhibits for Cox
32004-67-4 sc-200118
sc-200118A
5 mg
25 mg
$61.00
$215.00
2
(1)
Pravadoline
Pravadoline is a cannabimimetic analgesic and Cox-1 and Cox-2 inhibitor
92623-83-1 sc-200369
sc-200369A
5 mg
25 mg
$47.00
$251.00
0
(0)
Gallic acid
Gallic acid is a cyclooxygease inhibitor substance found in plants
149-91-7 sc-205704
sc-205704A
sc-205704B
10 g
100 g
500 g
$41.00
$64.00
$147.00
2
(1)
Zaltoprofen
Zaltoprofen is an inhibitor of Cox-1 and Cox-2
74711-43-6 sc-213173
sc-213173A
10 mg
100 mg
$130.00
$290.00
1
(1)
5-Nitro-2-(3-phenylpropylamino)benzoic Acid (NPPB)
5-Nitro-2-(3-phenylpropylamino)benzoic Acid (NPPB) is a Cox inhibitor and GPR35 activator
107254-86-4 sc-201542
sc-201542A
10 mg
50 mg
$52.00
$227.00
6
(1)
HET-0016
HET-0016 is a potent and selective inhibitor of the biosynthesis of 20-HETE
339068-25-6 sc-200673B
sc-200673
sc-200673D
sc-200673A
sc-200673C
1 mg
5 mg
10 mg
25 mg
100 mg
$18.00
$84.00
$144.00
$325.00
$1,080.00
5
(1)
(R)-Flurbiprofen
(R)-Flurbiprofen is an inhibitor of γ-secretase and Cox
51543-40-9 sc-205487
sc-205487A
10 mg
50 mg
$20.00
$60.00
0
(0)
Phenidone
Phenidone is a dual LO (lipoxygenase) and Cox (cyclooxygenase) inhibitor
92-43-3 sc-200508
5 g
$30.00
0
(0)
Fenoprofen
Fenoprofen is a compound that blocks cyclooxygenases
29679-58-1 sc-204752
sc-204752A
sc-204752B
250 mg
1 g
5 g
$257.00
$640.00
$1,950.00
1
(0)
Diclofenac-d4
Diclofenac-d4 is a nonsteroidal anti-inflammatory compound and a COX inhibitor
153466-65-0 sc-207562
sc-207562A
1 mg
10 mg
$280.00
$2,250.00
1
(1)
Phenylbutazone
Phenylbutazone is an inhibitor of Cox
50-33-9 sc-204843
5 g
$30.00
1
(0)
D-(-)-Salicin
D-(−)-Salicin is an inhibitor of Cox
138-52-3 sc-218004
5 g
$33.00
0
(0)
Ketoprofen
Ketoprofen is an inhibitor of Cox-1 and Cox-2
22071-15-4 sc-205359
sc-205359A
5 g
25 g
$86.00
$297.00
0
(0)
8,11,14-Eicosatriynoic Acid
8,11,14-Eicosatriynoic Acid is a Cox, 12-LO, and 5-LO inhibitor
34262-64-1 sc-221152
sc-221152A
1 mg
5 mg
$132.00
$595.00
0
(0)
Nabumetone
Nabumetone is a non-steroidal COX II inhibitor that reduces production of prostaglandins
42924-53-8 sc-204813
sc-204813A
5 g
25 g
$86.00
$300.00
1
(1)
Avarol
Avarol is a cytostatic agent which has potent antileukemic activity
55303-98-5 sc-202480
1 mg
$130.00
0
(0)
Talniflumate
Talniflumate is an inhibitor of Cox and Cl-/HCO3- exchange
66898-62-2 sc-203706
sc-203706A
10 mg
50 mg
$85.00
$359.00
0
(0)
Thielavin A
Thielavin A is apotent prostaglandin synthetase inhibitor
71950-66-8 sc-202361
500 µg
$298.00
0
(0)
Thielavin B
Thielavin B is an inhibitor peptidoglycan formation, prostaglandin biosynthesis, and PLC
71950-67-9 sc-202362
500 µg
$307.00
0
(1)
SKF 86002
SKF 86002 is an inhibitor of p53, Cox, and 5-LO
72873-74-6 sc-203265
5 mg
$153.00
0
(0)
Loxoprofen sodium
CAS: 80382-23-6, MF: C15H17O3 Na, MW: 268.286, Purity: ≥98%
80382-23-6 sc-279283
1 g
$300.00
0
(0)
(+/-)14,15-Epoxyeicosa-5Z,8Z,11Z-trienoic acid
(±)14,15-Epoxyeicosa-5Z,8Z,11Z-trienoic acid is a Cox inhibitor
81276-03-1 sc-220607
sc-220607A
50 µg
1 mg
$72.00
$803.00
0
(0)
Licofelone
Licofelone is an inhibitor of Cox-1, Cox-2, and 5-lipoxygenase
156897-06-2 sc-207826
sc-207826A
sc-207826B
sc-207826C
5 mg
250 mg
1 g
4 g
$60.00
$240.00
$800.00
$3,200.00
3
(1)
SC236
SC236 is a highly selective and potent inhibitor of Cox-2 and Cox-1
170569-86-5 sc-222298
sc-222298A
5 mg
25 mg
$77.00
$304.00
0
(0)
TFAP
TFAP is a selective inhibitor of Cox-1
1011244-68-0 sc-364633
10 mg
$194.00
0
(0)
4prime-Hydroxy Diclofenac-D4 (Major)
4′-Hydroxy Diclofenac-D4 (Major) is Labeled metabolite of the NSAID and COX inhibitor compound Diclofenac
254762-27-1 sc-206953
0.5 mg
$500.00
0
(0)
2,4,5-Trimethoxybenzaldehyde
2,4,5-Trimethoxybenzaldehyde is a selective Cox-2 inhibitor
4460-86-0 sc-238357
sc-238357A
25 g
100 g
$51.00
$177.00
0
(0)
8,11-Eicosadiynoic Acid
8,11-Eicosadiynoic Acid is a Cox, arachidonoyl synthase, and acyl-CoA synthase inhibitor
82073-91-4 sc-205179
sc-205179A
1 mg
5 mg
$80.00
$391.00
0
(0)
BTB 02472
BTB 02472 is an active-site-targeting Cox-2 inhibitor
1177728-24-3 sc-364449
25 mg
$209.00
0
(0)
SB 203580
SB 203580 is a pyridinyl imidazole that suppresses p38 mediated activation of MK2.
152121-47-6 sc-3533
sc-3533A
1 mg
5 mg
$84.00
$332.00
210
(4)
Resveratrol
Resveratrol is a natural phenolic antioxidant that is a potent activator of SIRT1 and inhibitor of Cox-1
501-36-0 sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$53.00
$175.00
$350.00
22
(2)
(R)-Ibuprofen
(R)-Ibuprofen is an inhibitor of Cox-1 and Cox-2
51146-57-7 sc-200625
200 mg
$126.00
2
(1)
Acetaminophen
Acetaminophen is a Cox-1, Cox-2, and Cox-3 (cyclooxygenase) inhibitor
103-90-2 sc-203425
sc-203425A
sc-203425B
5 g
100 g
500 g
$20.00
$25.00
$114.00
3
(1)
MK-886 sodium salt
MK-886 sodium salt is a potent and selective inhibitor of FLAP and Cox-1
118427-55-7 sc-200608B
sc-200608
sc-200608A
1 mg
5 mg
25 mg
$45.00
$91.00
$364.00
3
(1)
Diclofenac Sodium
Diclofenac Sodium is an inhibitor of Cox-1 and Cox-2
15307-79-6 sc-202136
sc-202136A
5 g
25 g
$28.00
$116.00
0
(1)
Naproxen
Naproxen is a Cox-1 and Cox-2 inhibitor
22204-53-1 sc-200506
sc-200506A
1 g
5 g
$24.00
$39.00
0
(1)
Meclofenamate sodium
Meclofenamate sodium is an inhibitor of 5-LO, Cox-1, and Cox-2
6385-02-0 sc-200532
sc-200532A
1 g
5 g
$50.00
$75.00
0
(0)
Ibuprofen
Ibuprofen is a Cox-1 and Cox-2 inhibitor
1189866-35-0 (unlabeled) sc-200534
sc-200534A
1 g
5 g
$44.00
$78.00
2
(0)
Piroxicam
Piroxicam is an inhibitor of prostaglandin synthesis as well as Cox-1 and Cox-2
36322-90-4 sc-200576
sc-200576A
1 g
5 g
$44.00
$180.00
2
(0)
6-Methoxy-2-Naphthylacetic acid
6-Methoxy-2-Naphthylacetic acid is a competitive and selective inhibitor of Cox-2
23981-47-7 sc-200602
sc-200602A
10 mg
50 mg
$82.00
$325.00
4
(0)
Sedanolide
Sedanolide is an inducer of GST and inhibitor of Cox-1, Cox-2, Topo I, Topo II, and carcinogenesis
6415-59-4 sc-205972
100 mg
$148.00
0
(1)
Ebselen
Ebselen is a cysteine modifier that inhibits 5-LO, 15-LO, Cox, NADPH, and NADPH oxidase
60940-34-3 sc-200740B
sc-200740
sc-200740A
1 mg
25 mg
100 mg
$20.00
$125.00
$435.00
4
(1)
cis-Resveratrol Solution (in Ethanol)
cis-Resveratrol Solution (in Ethanol) is an antioxidant antiproliferative compound shown to inhibit Cox-1
61434-67-1 sc-205254
sc-205254A
5 mg
10 mg
$120.00
$228.00
2
(1)
Indomethacin
Indomethacin is an inhibitor of Cox-1 and activator of PPARγ
53-86-1 sc-200503
sc-200503A
1 g
5 g
$23.00
$31.00
7
(1)
Radicicol
Radicicol is a potent inhibitor of HSP 90, SRC, and Cox-2
12772-57-5 sc-200620
sc-200620A
1 mg
5 mg
$80.00
$320.00
13
(1)
9-cis-Retinoic acid
9-cis-Retinoic acid is a Cox-2 inhibitor that prevents cell proliferation and induces cell differentiation
5300-03-8 sc-205589
sc-205589A
sc-205589B
1 mg
5 mg
25 mg
$64.00
$135.00
$400.00
3
(1)
Curcumin (Synthetic)
Curcumin (Synthetic) is reported to suppress COX-1, COX-2, NF-κB and other inflammatory mediators
458-37-7 sc-294110
sc-294110A
5 g
25 g
$50.00
$150.00
2
(1)
A77 1726
A77 1726 is an active metabolite of leflunomide that inhibits Cox-2
163451-81-8 sc-207235
10 mg
$55.00
11
(1)
Nimesulide
Nimesulide is a selective Cox-2 inhibitor
51803-78-2 sc-200623
5 g
$71.00
0
(0)
(S)-Ketoprofen
(S)-Ketoprofen is an inhibitor of TXB2 generation and of Cox
22161-81-5 sc-200624
1 g
$114.00
0
(1)
Meloxicam
Meloxicam is an inhibitor of Cox-1 and Cox-2, selective for Cox-2
71125-38-7 sc-200626
sc-200626A
sc-200626B
20 mg
100 mg
500 mg
$34.00
$90.00
$150.00
2
(1)
Deguelin
Deguelin is an inhibitor of Cox-2
522-17-8 sc-200657
sc-200657A
sc-200657B
5 mg
25 mg
500 mg
$67.00
$268.00
$1,821.00
1
(1)
APHS
APHS is a anti-inflammatory, selective, and potent Cox-2 inhibitor
209125-28-0 sc-200668
sc-200668B
10 mg
100 mg
$250.00
$2,000.00
0
(0)
Niflumic acid
Niflumic acid is a selective Cox-2 inhibitor and GPR35 activator
4394-00-7 sc-204820
5 g
$30.00
2
(1)
Xanthorrhizol
Xanthorrhizol is a pro-apoptotic inhibitor of Cox-2 and NOS2
30199-26-9 sc-202855
1 mg
$150.00
1
(1)
(S)-Ibuprofen
(S)-Ibuprofen is an inhibitor of Cox-1 and Cox-2
51146-56-6 sc-200612
sc-200612A
1 g
5 g
$41.00
$132.00
1
(1)
NS-398
NS-398 is a selective Cox-2 inhibitor neuroprotective agent
123653-11-2 sc-200604
sc-200604A
5 mg
25 mg
$82.00
$325.00
4
(1)
Pranoprofen
Pranoprofen is a non-steroidal antiinflammatory
52549-17-4 sc-205814
sc-205814A
100 mg
250 mg
$75.00
$180.00
0
(1)
Phenacetin
Phenacetin is a Cox-3 inhibitor
62-44-2 sc-257998
sc-257998A
50 g
250 g
$24.00
$55.00
3
(0)
Geniposidic acid
27741-01-1 sc-357361
sc-357361A
5 mg
25 mg
$162.00
$487.00
0
(0)
ETYA
ETYA is a Cox, LO, and PLA2 inhibitor
1191-85-1 sc-200764
sc-200764A
20 mg
100 mg
$74.00
$307.00
1
(1)
Flurbiprofen
Flurbiprofen is a potent inhibitor of Cox-1 and Cox-2
5104-49-4 sc-202158
sc-202158A
100 mg
1 g
$68.00
$102.00
0
(1)
Leflunomide
Leflunomide is an inhibitor of Cox-2 and tyrosine kinase
75706-12-6 sc-202209
sc-202209A
10 mg
50 mg
$20.00
$79.00
3
(1)
4'-Hydroxy Diclofenac
4′-Hydroxy Diclofenac is an active metabolite of Aceclofenac and Cox-2 inhibitor
64118-84-9 sc-202423
sc-202423A
1 mg
5 mg
$167.00
$600.00
2
(0)
Aspirin
Aspirin is an inhibitor of COX-1 (cylooxygenase) and NFκB
50-78-2 sc-202471
sc-202471A
5 g
50 g
$20.00
$40.00
3
(1)
Diclofenac Acyl-β-D-glucuronide
Diclofenac Acyl-β-D-glucuronide is a non-steroidal anti-inflammatory compound and COX inhibitor
64118-81-6 sc-207559
sc-207559A
sc-207559B
sc-207559C
1 mg
2 mg
5 mg
10 mg
$300.00
$560.00
$1,400.00
$2,400.00
0
(1)
COX-1 Inhibitor II
COX-1 Inhibitor II is a selective inhibitor of Cox-1
304913-22-2 sc-202556
25 mg
$195.00
0
(0)
COX-2 Inhibitor V, FK3311
COX-2 Inhibitor V, FK3311 is a selective Cox-2 inhibitor and NSAID
116686-15-8 sc-202557
5 mg
$199.00
0
(0)
Kaempferol
Kaempferol is an inhibitor of Fatty Acid Synthase, COX-1 activity, and Topo I
520-18-3 sc-202679
sc-202679A
sc-202679B
25 mg
100 mg
1 g
$85.00
$198.00
$480.00
3
(1)
N-tert-Butyl-a-phenylnitrone
N-tert-Butyl-a-phenylnitrone is a Cox-2 inhibitor
3376-24-7 sc-202722
500 mg
$50.00
0
(1)
SC 560
SC 560 is a highly potent and selective inhibitor of Cox-1
188817-13-2 sc-202805
5 mg
$67.00
0
(1)
4-Acetaminophen-d3 Sulfate Potassium Salt
4-Acetaminophen-d3 Sulfate Potassium Salt is a labeled metabolite of Acetaminophen
1188263-45-7 sc-216758
1 mg
$200.00
0
(0)
Sulindac
Sulindac is an inhibitor of the NF-κB pathway and a Cox inhibitor
38194-50-2 sc-202823
sc-202823A
sc-202823B
1 g
5 g
10 g
$30.00
$82.00
$144.00
2
(1)
Tryptanthrin
Tryptanthrin is a potent inhibitor of Cox-2 and NOS II
13220-57-0 sc-202844
sc-202844A
1 mg
5 mg
$50.00
$213.00
0
(0)
Cinnamtannin B-1
Cinnamtannin B-1 is a potent antioxidant and Cox-2 inhibitor
88082-60-4 sc-202997
5 mg
$237.00
0
(1)
Fexofenadine HCl
Fexofenadine HCl is an antihistamine that inhibits Cox-1, Cox-2, and is a histamine H1 receptor agonist
153439-40-8 sc-203047
sc-203047A
10 mg
50 mg
$95.00
$399.00
0
(0)
Pterostilbene, Pterocarpus marsupium
Pterostilbene, Pterocarpus marsupium is a Cox-1 and Cox-2 inhibitor
537-42-8 sc-203223
10 mg
$203.00
0
(0)
4prime-Hydroxy Diclofenac-13C6
4′-Hydroxy Diclofenac-13C6 is a labeled metabolite of Diclofenac
64118-84-9 (unlabeled) sc-217053
1 mg
$500.00
0
(0)
FR 122047 hydrochloride
FR 122047 hydrochloride is a highly selective Cox-1 inhibitor
130717-51-0 sc-203584
sc-203584A
10 mg
50 mg
$155.00
$620.00
0
(0)
SC 58125
SC 58125 is a selective Cox-2 inhibitor
162054-19-5 sc-204267
sc-204267A
10 mg
50 mg
$113.00
$550.00
0
(0)
Tenidap
Tenidap is a 5-LO and selective Cox-1 inhibitor
120210-48-2 sc-204334
sc-204334A
10 mg
50 mg
$129.00
$548.00
1
(1)
Etodolac
Etodolac is a Cox-2 inhibitor with anti-inflammatory activity
41340-25-4 sc-204747
sc-204747A
100 mg
250 mg
$85.00
$125.00
0
(1)
7Z,10Z,13Z,16Z,19Z-Docosapentaenoic acid
7Z,10Z,13Z,16Z,19Z-Docosapentaenoic acid is a fatty acid shown to inhibit platelet aggregation
24880-45-3 sc-200786
sc-200786A
1 mg
10 mg
$39.00
$64.00
0
(0)
3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole
3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole is a dual inhibitor of Cox-2 and 5-L
443919-96-8 sc-205108
sc-205108A
1 mg
5 mg
$90.00
$406.00
0
(0)
Phenylbutazone-d9
Phenylbutazone-d9 is an inhibitor of Cox (cyclooxygenase)
sc-219606
2.5 mg
$280.00
0
(0)
9,12-Octadecadiynoic Acid
9,12-Octadecadiynoic Acid is an inhibitor of Cox and LO
2012-14-8 sc-205191
sc-205191A
1 mg
5 mg
$80.00
$360.00
0
(0)
Ketorolac (tromethamine salt)
Ketorolac (tromethamine salt) is a non selective inhibitior of Cox-1 and Cox-2
74103-07-4 sc-205360
sc-205360A
500 mg
1 g
$20.00
$50.00
2
(0)
NO-Indomethacin
NO-Indomethacin is a Cox-1 and Cox-2 inhibitor and NO donor
301838-28-8 sc-205414
sc-205414A
sc-205414B
sc-205414C
1 mg
5 mg
10 mg
50 mg
$25.00
$108.00
$192.00
$849.00
0
(0)
(S)-(+)-Flurbiprofen
(S)-(+)-Flurbiprofen is an inhibitor of Cox-1 and Cox-2
51543-39-6 sc-205503
sc-205503A
10 mg
50 mg
$25.00
$113.00
0
(0)
DuP-697
DuP-697 is a thiophene that inhibits Cox-2
88149-94-4 sc-200680
sc-200680A
5 mg
25 mg
$114.00
$465.00
0
(1)
Lumaricoxib
Lumaricoxib is a Cox-2 selective inhibitor and NSAID
220991-20-8 sc-205736
sc-205736A
100 mg
250 mg
$140.00
$280.00
0
(0)
Rutaecarpine
Rutaecarpine is an inhibitor of Cox-2 and platelet aggregation
84-26-4 sc-205846
sc-205846A
10 mg
25 mg
$123.00
$359.00
1
(0)
Valeryl salicylate
Valeryl salicylate is a selective inhibitor of Cox-1
64206-54-8 sc-205985
100 mg
$87.00
0
(0)
N-(4-Acetamidophenyl)indomethacin Amide
N-(4-Acetamidophenyl)indomethacin Amide is a selective reversible Cox-2 inhibitor
261766-23-8 sc-207912
50 mg
$250.00
0
(0)
Vioxx
Vioxx is a selective Cox-2 inhibitorthat has anti-inflammatory properties
162011-90-7 sc-208486
100 mg
$146.00
3
(1)
7-(Trifluoromethyl)1H-indole-2,3-dione
391-12-8 sc-217411
100 mg
$250.00
0
(0)
Naproxen Sodium Salt
Naproxen Sodium Salt is a nonselective inhibitor of Cox-1 and Cox-2
26159-34-2 sc-212361
25 g
$177.00
1
(0)
(S)-(+)-Ketoprofen
(S)-(+)-Ketoprofen is a Cox inhibitor
22161-81-5 sc-212844
100 mg
$83.00
0
(0)
Meloxicam sodium salt
Meloxicam sodium salt is a Cox-2 inhibitor
71125-39-8 sc-215294
100 mg
$177.00
1
(0)
N-(2-Phenylethyl)indomethacin Amide
N-(2-Phenylethyl)indomethacin Amide is an inhibitor of Cox-2
261766-32-9 sc-218925
50 mg
$250.00
0
(0)
N-(3-Pyridyl)indomethacin Amide
N-(3-Pyridyl)indomethacin Amide is a potent and selective reversible Cox-2 inhibitor
261755-29-4 sc-218939
50 mg
$250.00
0
(0)
COX-2 Inhibitor I
COX-2 Inhibitor I is an inhibitor of Cox-2
416901-58-1 sc-221436
5 mg
$257.00
0
(0)
COX-2 Inhibitor II
COX-2 Inhibitor II is a selective inhibitor of Cox-2
181696-33-3 sc-221437
5 mg
$270.00
0
(0)
FR122047 monohydrate
FR122047 monohydrate is a highly selective Cox-1 inhibitor
sc-221628
sc-221628A
sc-221628B
sc-221628C
1 mg
5 mg
10 mg
50 mg
$25.00
$95.00
$168.00
$739.00
0
(0)
Indomethacin heptyl ester
Indomethacin heptyl ester is a selective Cox-2 inhibitor that reduces expression and activity of MDR-1
sc-221758
sc-221758A
1 mg
5 mg
$24.00
$108.00
0
(0)
CAY10589
CAY10589 is an inhibitor of 5-LO, Cox-1, and Cox-2
1077626-52-8 sc-223872
sc-223872A
1 mg
5 mg
$56.00
$255.00
0
(0)
ZLJ-6
ZLJ-6 is an inhibitor of Cox-1, Cox-2, and 5-LO
1051931-39-5 sc-224468
sc-224468A
1 mg
5 mg
$40.00
$180.00
0
(0)
YS121
YS121 is an inhibitor of mPGES-1, 5-LO, Cox-1, and Cox-2
916482-17-2 sc-296707
sc-296707A
1 mg
5 mg
$56.00
$251.00
0
(0)
NCX 4040
NCX 4040 is an inhibitor of Cox-2 expression
287118-97-2 sc-364547
sc-364547A
5 mg
25 mg
$73.00
$221.00
0
(0)
MEG, Hydrochloride
MEG, Hydrochloride is a NOS2, Cox-1, and Cox-2 inhibitor
19767-44-3 sc-364694
10 mg
$225.00
0
(0)
(E)-3,5,4prime-Tribenzyloxystilbene
CAS: 89946-06-5, MF: C35H30O3, MW: 498.61
89946-06-5 sc-474967
1 g
$300.00
0
(0)

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