Heterobifunctional Crosslinkers
Santa Cruz Biotechnology now offers a broad range of Heterobifunctional Crosslinkers. Heterobifunctional Crosslinkers contain two different reactive functional groups that are separated at various lengths. The reactive ends are chosen for their particular chemoselective properties, often targeting the primary amines and sulfhydryl groups of proteins. Our popular products such as N-Succinimidyl Iodoacetate, 3-(2-Pyridyldithio)propionic Acid N-Succinimidyl Ester, and 4-(4-Maleimidophenyl)butyric acid N-hydroxysuccinimide ester are typically available for immediate shipment.
indicates a highly recommended product based on customer preference.
| PRODUCT NAME/Application | CAS | Catalog # | QUANTITY | Price | Citations | RATING | |
|---|---|---|---|---|---|---|---|
6-Maleimidocaproic Acid Sulfo-N-Succinimidyl Ester6-Maleimidocaproic Acid Sulfo-N-Succinimidyl Ester is a water-soluble, heterobifunctional amine- and sulfhydryl-reactive crosslinker, 9.4 angstrom spacer |
215312-86-0 |
sc-217352 sc-217352A |
100 mg 10 mg |
$280.00
$70.00 |
0 |
| |
Maleimidoacetic Acid N-Hydroxysuccinimide EsterMaleimidoacetic Acid N-Hydroxysuccinimide Ester is a heterobifunctional amine- and sulfhydryl-reactive crosslinker |
55750-61-3 |
sc-211769 |
50 mg |
$350.00
|
0 |
| |
Sulfo-SMCCSulfo-SMCC is a sulfhydryl- and amine-reactive crosslinker |
92921-24-9 |
sc-212979 sc-212979A sc-212979B |
10 mg 100 mg 1 g |
$72.00
$400.00 $1,800.00 |
0 |
| |
SMCCSMCC is a heterobifunctional sulfhydryl- and amine- reactive crosslinker, 11.6 Angstrom spacer arm |
64987-85-5 |
sc-212277 sc-212277A sc-212277B |
25 mg 100 mg 1 g |
$64.00
$158.00 $300.00 |
0 |
| |
5-Azido-2-nitrobenzoic acid N-hydroxysuccinimide ester5-Azido-2-nitrobenzoic acid N-hydroxysuccinimide ester is a nitrate-containing, aryl azide-based, amine- and photoreactive crosslinker |
60117-35-3 |
sc-256884 |
100 mg |
$222.00
|
0 |
| |
Benzophenone-4-isothiocyanateBenzophenone-4-isothiocyanate is a benzophenone-based, hydroxyl- and photoreactive crosslinker |
26328-59-6 |
sc-214587 |
100 mg |
$183.00
|
1 |
| |
N-Succinimidyl IodoacetateN-Succinimidyl Iodoacetate is an amine and sulfhydryl reactive crosslinker, 1.5 angstrom spacer arm |
39028-27-8 |
sc-212279 |
100 mg |
$234.00
|
0 |
| |
N-Hydroxysuccinimidyl-4-azidobenzoateN-Hydroxysuccinimidyl-4-azidobenzoate is an aryl azide-based, amine- and photoreactive crosslinker |
53053-08-0 |
sc-263835 |
100 mg |
$126.00
|
0 |
| |
p-Azidophenacyl Bromidep-Azidophenacyl Bromide is an aryl azide-based, sulfhydryl- and photoreactive crosslinker |
57018-46-9 |
sc-212500 |
1 g |
$500.00
|
0 |
| |
N-Succinimidyl-p-FormylbenzoateN-Succinimidyl-p-Formylbenzoate is A amino-reactive crosslinking reagent that is heterobifunctional |
60444-78-2 |
sc-212281 sc-212281A sc-212281B |
100 mg 250 mg 1 g |
$125.00
$210.00 $550.00 |
0 |
| |
3-(2-Pyridyldithio)propionic Acid N-Succinimidyl Ester3-(2-Pyridyldithio)propionic Acid N-Succinimidyl Ester is An amine- and sulfhydryl- reactive crosslinker, 4 atom spacer arm |
68181-17-9 |
sc-209453 |
100 mg |
$350.00
|
0 |
| |
4-(4-Maleimidophenyl)butyric acid N-hydroxysuccinimide ester4-(4-Maleimidophenyl)butyric acid N-hydroxysuccinimide ester is an amine and sulfhydryl reactive crosslinker, 11.6 angstrom spacer arm |
79886-55-8 |
sc-252087 |
25 mg |
$110.00
|
0 |
| |
4-Maleimidobutyric Acid N-Succinimidyl Ester4-Maleimidobutyric Acid N-Succinimidyl Ester is An amine- and sulfhydryl-reactive crosslinker |
80307-12-6 |
sc-210101 |
100 mg |
$217.00
|
0 |
| |
4-[3-(Trifluoromethyl)diazirin-3-yl]benzoic Acid N-Hydroxysuccinimide Ester4-[3-(Trifluoromethyl)diazirin-3-yl]benzoic Acid N-Hydroxysuccinimide Ester is a photoaffinity label and crosslinking reagent. |
87736-89-8 |
sc-209897A sc-209897 sc-209897B sc-209897C sc-209897D |
1 mg 2.5 mg 5 mg 10 mg 25 mg |
$190.00
$250.00 $471.00 $900.00 $2,000.00 |
0 |
| |
4-(N-Succinimidylcarboxy)benzophenone4-(N-Succinimidylcarboxy)benzophenone is a benzophenone-based, amine- and photoreactive crosslinker |
91990-88-4 |
sc-209864 |
25 mg |
$220.00
|
0 |
| |
N-Succinimidyl 4-Azido-2,3,5,6-tetrafluorobenzoateN-Succinimidyl 4-Azido-2,3,5,6-tetrafluorobenzoate is a fluorinated, aryl azide-based, amine- and photoreactive crosslinker |
126695-58-7 |
sc-208056 sc-208056A |
50 mg 100 mg |
$100.00
$190.00 |
0 |
| |
SASDSASD is a hydroxyl-containing, aryl azide-based, amine- and photoreactive crosslinker, 18.9 angstrom spacer arm |
144650-95-3 |
sc-220093 |
10 mg |
$250.00
|
0 |
| |
6-Maleimidocaproic Acid Hydrazide, Trifluoroacetic Acid6-Maleimidocaproic Acid Hydrazide, Trifluoroacetic Acid is a maleimade derivative |
151038-94-7 |
sc-210528 |
50 mg |
$165.00
|
0 |
| |
Succinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoateSuccinimidyl 6-[3-(2-Pyridyldithio)propionamido]hexanoate is a long chain amine and sulfhydryl reactive crosslinker, 11 atom spacer arm |
158913-22-5 |
sc-212962 |
10 mg |
$150.00
|
0 |
| |
4-(Maleimidomethyl)cyclohexane-1-carboxyl-hydrazide, Trifluoroacetic Acid4-(Maleimidomethyl)cyclohexane-1-carboxyl-hydrazide, Trifluoroacetic Acid is a heterobifunctional crosslinking reagent |
181148-00-5 |
sc-209848 |
10 mg |
$250.00
|
0 |
| |
N-Succinimidyloxycarbonylethyl MethanethiosulfonateN-Succinimidyloxycarbonylethyl Methanethiosulfonate is a heterobifunctional and sulfhydryl reactive crosslinker |
385399-11-1 |
sc-212284 |
10 mg |
$280.00
|
0 |
| |
N-Succinimidyloxycarbonylpropyl MethanethiosulfonateN-Succinimidyloxycarbonylpropyl Methanethiosulfonate is a reagent for heterobifunctional sulfhydryl cross-linking |
690632-55-4 |
sc-219231 |
10 mg |
$280.00
|
0 |
| |
6-Maleimidohexanoic acid N-hydroxysuccinimide ester6-Maleimidohexanoic acid N-hydroxysuccinimide ester is a heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity |
55750-63-5 |
sc-239101 |
100 mg |
$81.00
|
0 |
| |
N-Succinimidyl (4-Iodoacetyl)-aminobenzoateN-Succinimidyl (4-Iodoacetyl)-aminobenzoate is A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent |
72252-96-1 |
sc-219221 |
10 mg |
$220.00
|
0 |
| |
3-(2-Pyridyldithio)propanoic Acid Hydrazide3-(2-Pyridyldithio)propanoic Acid Hydrazide is a fluorescent sulfhydryl active reagent |
115616-51-8 |
sc-209452 |
5 mg |
$280.00
|
0 |
| |
Sulfo-N-succinimidyl (N-Iodoacetyl)aminobenzoateSulfo-N-succinimidyl (N-Iodoacetyl)aminobenzoate is a water soluble amine and sulfhydryl reactive crosslinker, 10.6 angstrom spacer arm |
144650-93-1 |
sc-358557 |
25 mg |
$220.00
|
0 |
| |
N-Succinimidyl 6-(3-Maleimidopropionamido) HexanoateN-Succinimidyl 6-(3-Maleimidopropionamido) Hexanoate is a reagent for sulfhydryl and amino reactive heterobifunctional crosslinking |
sc-219226 |
10 mg |
$220.00
|
0 |
| ||
N-Succinimidyl BromoacetateN-Succinimidyl Bromoacetate is an amine and sulfhydryl reactive crosslinker, 1.5 angstrom spacer arm |
42014-51-7 |
sc-212278 |
100 mg |
$200.00
|
0 |
| |
N-Succinimidyl 3-(Bromoacetamido)propionateN-Succinimidyl 3-(Bromoacetamido)propionate is an amine and sulfhydryl reactive crosslinker, 6.2 Angstrom spacer arm |
57159-62-3 |
sc-212276 |
10 mg |
$280.00
|
0 |
| |
3-N-Maleimidobenzoic Acid N-Succinimidyl Ester3-N-Maleimidobenzoic Acid N-Succinimidyl Ester is a heterobifunctional amine- and sulfhydryl-reactive crosslinker, 9.9 Angstrom spacer arm |
58626-38-3 |
sc-209654 |
250 mg |
$220.00
|
0 |
| |
6-(4-Azido-2-nitrophenylamino)hexanoic acid N-hydroxysuccinimide ester6-(4-Azido-2-nitrophenylamino)hexanoic acid N-hydroxysuccinimide ester is a photoactive, heterobifunctional cross-linking reagent |
64309-05-3 |
sc-256960 |
50 mg |
$516.00
|
0 |
| |
N-Succinimidyloxycarbonylpentyl MethanethiosulfonateN-Succinimidyloxycarbonylpentyl methanethiosulfonate is a heterobifunctional amine- and sulfhydryl-reactive crosslinker |
76078-81-4 |
sc-212285 |
10 mg |
$210.00
|
0 |
| |
4-(Maleimido)benzophenone4-(Maleimido)benzophenone is a benzophenone-based, sulfhydryl-reactive photoreactive crosslinker |
92944-71-3 |
sc-209847 |
100 mg |
$142.00
|
1 |
| |
N-Succinimidyl 4-AzidosalicylateN-Succinimidyl 4-Azidosalicylate is a hydroxyl-containing, photoreactive aryl azide-based crosslinker for 125I radiolabeling |
96602-46-9 |
sc-219224 |
50 mg |
$300.00
|
0 |
| |
Sulphosuccinimidyl 6-(4prime-azido-2prime-nitrophenylamino)hexanoateSulphosuccinimidyl 6-(4′-azido-2′-nitrophenylamino)hexanoate is a nitrate-containing, aryl azide-based, amine- and photoreactive crosslinker |
102568-43-4 |
sc-355990 |
100 mg |
$300.00
|
0 |
| |
4-Maleimidophenyl isocyanate4-Maleimidophenyl isocyanate is a novel heterobifunctional crosslinker for hydroxyl-to-thiol coupling |
123457-83-0 |
sc-352445 |
50 mg |
$473.00
|
0 |
| |
N-Succinimidyl 6-[[4-(Maleimidomethyl)cyclohexyl]carboxamido] Caproate |
125559-00-4 |
sc-219227 |
10 mg |
$220.00
|
0 |
| |
S-[2-(4-Azidosalicylamido)ethylthio]-2-thiopyridineS-[2-(4-Azidosalicylamido)ethylthio]-2-thiopyridine is a radioionatable, cleavable, photoactivable cross linking agent |
164575-82-0 |
sc-212808 |
10 mg |
$280.00
|
0 |
| |
Sulfo-N-succinimidyl 6-[3-(2-Pyridyldithio)propionamido] Hexanoate, Sodium Salt |
169751-10-4 |
sc-208407 |
5 mg |
$300.00
|
0 |
| |
S-[2-(Iodo-4-Azidosalicylamido)ethylthio]-2-thiopyridine |
175093-14-8 |
sc-212809 |
5 mg |
$280.00
|
0 |
| |
11-Maleimidoundecanoic Acid Sulfo-N-Succinimidyl Ester |
211236-68-9 |
sc-213588 sc-213588A |
100 mg 250 mg |
$240.00
$500.00 |
0 |
| |
11-Maleimidoundecanoic Acid Hydrazide |
359436-62-7 |
sc-208849 |
10 mg |
$250.00
|
0 |
| |
3-(Benzophenone-4-carboxamido)-2-maleimidopropanoic acid3-(Benzophenone-4-carboxamido)-2-maleimidopropanoic acid is a maleimide derivative |
887352-68-3 |
sc-209472 |
5 mg |
$280.00
|
0 |
| |
4-(Maleimidomethyl)cyclohexane-1-carbonyl-1-(tert-butyl)carbazate |
887406-71-5 |
sc-216696 |
25 mg |
$250.00
|
0 |
| |
N-Succinimidyloxycarbonylheptyl Methanethiosulfonate |
887407-50-3 |
sc-219229 |
10 mg |
$250.00
|
0 |
| |
N-Succinimidyloxycarbonylpentadecyl Methanethiosulfonate |
887407-52-5 |
sc-219230 |
10 mg |
$200.00
|
0 |
| |
N-Succinimidyloxycarbonylundecyl MethanethiosulfonateN-Succinimidyloxycarbonylundecyl Methanethiosulfonate is a heterobifunctional amine- and sulfhydryl- reactive crosslinker |
887407-54-7 |
sc-212286 |
10 mg |
$280.00
|
0 |
| |
3-(Maleimidopropane-1-carbonyl-1-(tert-butyl)carbazate3-(Maleimidopropane-1-carbonyl-1-(tert-butyl)carbazate is A sulfhydryl and carbohydrate reactive, heterobifunctional crosslinking reagent. |
1076198-38-3 |
sc-357585 |
100 mg |
$250.00
|
0 |
| |
11-Maleimidoundecane-1-carbonyl-1-(t-butyl)carbazate |
1076198-39-4 |
sc-213587 |
25 mg |
$220.00
|
0 |
| |
Maleimide-PEG2-NHSMaleimide-PEG2-NHS is a heterobifunctional amine- and sulfhydryl-reactive crosslinker, 17.6 angstrom ethylene oxide spacer arm |
955094-26-5 |
sc-397274 sc-397274A |
50 mg 250 mg |
$150.00
$450.00 |
0 |
| |
Maleimide-PEG12-NHS esterMaleimide-PEG12-NHS ester is a heterobifunctional amine- and sulfhydryl-reactive crosslinker with a 53.3 angstrom ethylene oxide spacer arm |
1426151-00-9 |
sc-397277 sc-397277A |
50 mg 250 mg |
$340.00
$750.00 |
0 |
| |
monodisperse Mal-PEG4-NHS-estermonodisperse Mal-PEG4-NHS-ester is a monodispersed maleimide crosslinker with PEG spacers |
756525-99-2 |
sc-397273 |
100 mg |
$323.00
|
0 |
| |
Maleimide-PEG8-NHS esterMaleimide-PEG8-NHS ester is a heterobifunctional amine- and sulfhydryl-reactive crosslinker with a 39.2 angstrom ethylene oxide spacer arm |
756525-93-6 |
sc-397276 sc-397276A |
50 mg 250 mg |
$206.00
$599.00 |
0 |
| |
[N-(2-Maleimidoethyl]diethylenetriaminepentaacetic Acid, Monoamide[N-(2-Maleimidoethyl]diethylenetriaminepentaacetic Acid, Monoamide is A heterobifunctional crosslinking reagent |
180152-82-3 |
sc-218918 |
10 mg |
$2,400.00
|
0 |
| |
Sulfo-NHS-(PEG4-bismannose)-SS-biotinSulfo-NHS-(PEG4-bismannose)-SS-biotin is a cleavable biotinylated heterobifunctional cross-linking reagent |
sc-220171 |
250 µg |
$1,300.00
|
1 |
| ||
2-maleimidoethylamine hydrochloride2-maleimidoethylamine hydrochloride is a heterobifunctional linker |
134272-64-3 |
sc-265752 |
100 mg |
$83.00
|
0 |
| |
N-(2-Maleimidoethyl)-6-aminohexanamide, Trifluoroacetic Acid SaltN-(2-Maleimidoethyl)-6-aminohexanamide, Trifluoroacetic Acid Salt is a heterobifunctional crosslinking reagent |
1185075-13-1 |
sc-218916 |
10 mg |
$220.00
|
0 |
|