PKC Activators

Santa Cruz Biotechnology now offers a broad range of PKC Activators. Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKC Activators offered by Santa Cruz activate PKC and, in some cases, other cell growth and differentiation related proteins. View detailed PKC Activator specifications, including PKC Activator CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
Okadaic Acid
Okadaic Acid® is a naturally occurring polyether toxin that acts as a reversible, potent and selective inhibitor of protein phosphatatses.
78111-17-8 sc-3513
sc-3513A
sc-3513B
25 µg
100 µg
1 mg
$75.00
$200.00
$1,150.00
56
(4)
PMA
PMA is a reversible and highly potent protein kinase C (PKC) activator in vitro and in vivo at nM concentrations.
16561-29-8 sc-3576
sc-3576A
sc-3576B
sc-3576C
1 mg
5 mg
10 mg
25 mg
$33.00
$109.00
$200.00
$480.00
58
(6)
Bryostatin 1
Bryostatin 1 is a macrolactone marine natural product that binds to and modulates PKC
83314-01-6 sc-201407
10 µg
$184.00
5
(1)
1α,25-Dihydroxyvitamin D3
1α,25-Dihydroxyvitamin D3 is also known as Calcitriol, the active form of vitamin D3, and an activator of PKC and VDR
32222-06-3 sc-202877B
sc-202877
sc-202877A
sc-202877C
sc-202877D
50 µg
100 µg
1 mg
5 mg
10 mg
$197.00
$240.00
$620.00
$1,400.00
$2,000.00
21
(1)
Prostratin
Prostratin is a PKC (Protein Kinase C) activator and potential HIV infection inhibitor
60857-08-1 sc-203422
sc-203422A
1 mg
5 mg
$94.00
$376.00
20
(2)
1,2-Dioctanoyl-sn-glycerol
1,2-Dioctanoyl-sn-glycerol is a cell-permeable activator of protein kinase C (PKC)
60514-48-9 sc-202397
sc-202397A
10 mg
50 mg
$45.00
$244.00
0
(1)
1-Oleoyl-2-acetyl-sn-glycerol (OAG)
1-Oleoyl-2-acetyl-sn-glycerol (OAG) is a protein kinase C activating diacylglycerol
86390-77-4 sc-200417
sc-200417A
10 mg
50 mg
$105.00
$425.00
0
(1)
1-O-Hexadecyl-2-O-acetyl-sn-glycerol
1-O-Hexadecyl-2-O-acetyl-sn-glycerol is an inhibitor of protein kinase C activation
77133-35-8 sc-200516
5 mg
$98.00
0
(0)
α-Amyloid Precursor Protein Modulator
α-Amyloid Precursor Protein Modulator is a cell-permeable benzolactam derived PKC activator displaying a marked loss of tumor promoting activity.
497259-23-1 sc-204424
1 mg
$315.00
1
(1)
Oleic Acid
Oleic Acid is an anti-proliferative agent and activator of PKC and CaMKII
112-80-1 sc-200797C
sc-200797
sc-200797A
sc-200797B
1 g
10 g
100 g
250 g
$25.00
$90.00
$548.00
$1,140.00
4
(1)
Ingenol 3-angelate
Ingenol 3-angelate is a PKC activator, anticancer, and immunostimulant compound
75567-37-2 sc-364214
sc-364214A
1 mg
5 mg
$185.00
$720.00
1
(1)
DCP-LA
DCP-LA is a PKC-epsilon activator
28399-31-7 sc-255068
1 mg
$180.00
0
(1)
PIP2
PIP2 is a PKC activator and KIR3.4 inhibitor
383907-42-4 sc-391159
sc-391159A
100 µg
1 mg
$104.00
$431.00
1
(0)
Phorbol-12,13-dibutyrate
Phorbol-12,13-dibutyrate is a protein kinase C activator
37558-16-0 sc-202285
1 mg
$115.00
2
(1)
8(S)-HETE
8(S)-HETE is a fatty acid metabolite and potential PKC and PPARα activator
98462-03-4 sc-200940
50 µg
$226.00
0
(0)
Mezerein
Mezerein is a PKC activator and second stage tumor promoter
34807-41-5 sc-202707
1 mg
$338.00
1
(1)
Clomiphene Citrate
Clomiphene Citrate is a selective estrogen receptor modulator
50-41-9 sc-205636
sc-205636A
1 g
5 g
$55.00
$135.00
0
(0)
Sodium oleate
143-19-1 sc-215879
sc-215879A
250 mg
1 g
$32.00
$84.00
1
(1)
Phorbol-12,13-didecanoate
Phorbol 12,13-didecanoate is a strong NO promoter and potent protein kinase C activator
24928-17-4 sc-202286
1 mg
$68.00
1
(0)
1,2-Dipalmitoyl-sn-glycerol
1,2-Dipalmitoyl-sn-glycerol is a DAG analog and weak PKC activator
30334-71-5 sc-220517
sc-220517A
25 mg
100 mg
$31.00
$68.00
0
(0)
1-Stearoyl-2-linoleoyl-sn-glycerol
1-Stearoyl-2-linoleoyl-sn-glycerol is a protein kinase C activator
34487-26-8 sc-220504
sc-220504A
10 mg
50 mg
$105.00
$400.00
0
(0)
Phorbol 12, 13-Dihexanoate
Phorbol 12, 13-Dihexanoate is a potent and hydrophobic PKC activator
37558-17-1 sc-203421
sc-203421A
1 mg
5 mg
$75.00
$300.00
1
(1)
Resiniferonol 9,13,14-ortho-phenylacetate
Resiniferonol 9,13,14-ortho-phenylacetate is a derivative of resiniferatoxin not active as a capsaicin analog
57852-42-3 sc-202310
5 mg
$195.00
1
(0)
C-8 Ceramide
C-8 Ceramide is a ceramide analog
74713-59-0 sc-205233
sc-205233A
1 mg
5 mg
$19.00
$62.00
0
(0)
RHC-80267
RHC-80267 is a selective inhibitor of DAG lipase and PKC activator
83654-05-1 sc-222251
10 mg
$47.00
0
(1)
(+/-)-1-Oleoyl-2-acetylglycerol
(±)-1-Oleoyl-2-acetylglycerol is A potent and cell permeable activator of protein kinase C
86390-77-4 sc-287175
sc-287175A
sc-287175B
5 mg
10 mg
25 mg
$134.00
$364.00
$533.00
0
(1)
Bryostatin 2
Bryostatin 2 is a macrocyclic lactone and antagonist of phorbol ester action
87745-28-6 sc-202086
sc-202086A
10 µg
25 µg
$195.00
$578.00
1
(0)
Lipoxin A4
Lipoxin A4 is a trihydroxy fatty acid produced through 15-HETE metabolism
89663-86-5 sc-201060
sc-201060A
sc-201060B
sc-201060C
25 µg
50 µg
100 µg
250 µg
$330.00
$471.00
$900.00
$1,980.00
1
(1)
Myelin basic protein (4-14), N-acetylated
Myelin basic protein (4-14), N-acetylated is a specific substrate for α, β, γ isoforms of PKC
126768-94-3 non-acetylated sc-201155
1 mg
$262.00
0
(0)
1-O-Hexadecyl-2-O-methyl-rac-glycerol
1-O-Hexadecyl-2-O-methyl-rac-glycerol is an inhibitor of protein kinase C
111188-59-1 sc-201998
sc-201998A
250 mg
1 g
$196.00
$592.00
0
(0)
7-Oxostaurosporine
7-Oxostaurosporine is an oxidized and highly fluorescent analogue of Antibiotics UCN-01 and UCN-02
141196-69-2 sc-202027
1 mg
$369.00
1
(0)
(−)-Indolactam V
(−)-Indolactam V is a protein kinase C activator; also can direct the differentiation of human ESCs
90365-57-4 sc-202182
sc-202182A
300 µg
1 mg
$163.00
$275.00
1
(1)
SC9
SC9 is a Protein kinase C (PKC) activator in the presence of Ca2+
102649-78-5 sc-202336
sc-202336A
sc-202336B
1 mg
5 mg
50 mg
$30.00
$64.00
$560.00
0
(0)
SC10
SC10 is a protein kinase C (PKC) activator
102649-79-6 sc-202335
sc-202335A
1 mg
5 mg
$30.00
$100.00
0
(0)
Cholesterol 3-sulfate sodium salt
Cholesterol 3-sulfate sodium salt is an activator of multiple protein kinase C enzymes
2864-50-8 sc-202538
sc-202538A
5 mg
25 mg
$36.00
$57.00
0
(1)
Ingenol 3,20-dibenzoate
Ingenol 3,20-dibenzoate is an activator of protein kinase C (PKC) and apoptotic inducer
59086-90-7 sc-202663
sc-202663A
sc-202663B
sc-202663C
1 mg
5 mg
10 mg
100 mg
$600.00
$2,400.00
$3,500.00
$24,000.00
6
(1)
NPC-15437 dihydrochloride
NPC-15437 dihydrochloride is a selective protein kinase C (PKC) inhibitor
136449-85-9 sc-202742
sc-202742A
1 mg
5 mg
$102.00
$315.00
1
(1)
Zoledronic acid monohydrate
Zoledronic acid monohydrate is a highly potent bisphosphonate and activator of PKC
165800-06-6 sc-202859
sc-202859A
sc-202859B
25 mg
100 mg
1 g
$88.00
$278.00
$640.00
1
(1)
1-Stearoyl-2-arachidonoyl-sn-glycerol
1-Stearoyl-2-arachidonoyl-sn-glycerol is a diacylglycerol derivative and activator of PKC
65914-84-3 sc-202864
10 mg
$143.00
0
(1)
(+)-Indolactam V
(+)-Indolactam V is a negative control for (−)-indolactam V studies
90365-56-3 sc-203085
300 µg
$110.00
0
(0)
Hispidin
Hispidin is a cell permeable inhibitor of PKCβ
555-55-5 sc-203998
5 mg
$330.00
0
(0)
PKCbeta Inhibitor
PKCβ Inhibitor is an anilino-monoindolylmaleimide compound that is a potent inhibitor of PKCβ isozymes
257879-35-9 sc-204199
500 µg
$200.00
1
(1)
Safingol
Safingol is a lyso-sphingolipid protein kinase C inhibitor
15639-50-6 sc-204258
1 mg
$179.00
1
(1)
12-Deoxyphorbo 13-Angelate 20-Acetate
12-Deoxyphorbo 13-Angelate 20-Acetate is a weak tumor promoter (mouse skin)
25090-72-6 sc-287294
1 mg
$169.00
0
(0)
Sangivamycin
Sangivamycin is a cytotoxic purine nucleoside
18417-89-5 sc-204261
sc-204261A
sc-204261B
sc-204261C
sc-204261D
sc-204261E
1 mg
10 mg
25 mg
50 mg
100 mg
250 mg
$185.00
$592.00
$1,227.00
$2,100.00
$3,000.00
$4,800.00
0
(1)
TER14687
TER14687 is a compound preventing normal translocation of PKCq in T cells
16931-84-3 sc-204336
sc-204336A
10 mg
50 mg
$180.00
$750.00
0
(0)
6-(N-Decylamino)-4-Hydroxymethylindole
6-(N-Decylamino)-4-Hydroxymethylindole is a synthetic PKC activator
123597-55-7 sc-291161
sc-291161A
1 mg
5 mg
$100.00
$500.00
0
(0)
4alpha-Phorbol 12,13-dibutyrate
4α-Phorbol 12,13-dibutyrate is a negative control for sc-202285
93781-54-5 sc-352029
1 mg
$218.00
1
(0)
Zoledronic Acid, Disodium Salt, Tetrahydrate
Zoledronic Acid, Disodium Salt, Tetrahydrate is an inhibitor of biphosphonate bone resportion
165800-07-7 sc-208497
sc-208497A
sc-208497B
50 mg
100 mg
250 mg
$165.00
$410.00
$950.00
0
(1)
Arachidonic Acid methyl ester
Arachidonic Acid methyl ester is the keystone essential fatty acid at the origin of the arachidonic acid cascade
2566-89-4 sc-362322
50 mg
$83.00
0
(0)
Arachidonic Acid-d8
Arachidonic Acid-d8 is an internal standard for the quantification of arachidonic acid
69254-37-1 sc-205209
sc-205209A
1 mg
5 mg
$228.00
$785.00
1
(0)
Phorbol
Phorbol is a plant-derived diterpene that is a tumor promoter
17673-25-5 sc-253267
5 mg
$270.00
1
(0)
MDL-27,032
MDL-27,032 is a PKA and PKC inhibitor
110124-55-5 sc-205953
sc-205953A
100 µg
1 mg
$200.00
$400.00
0
(0)
rac-2-Ethoxy-3-octadecanamido-1-propylphosphocholine
rac-2-Ethoxy-3-octadecanamido-1-propylphosphocholine is a PKC (protein kinase C) inhibitor
163702-18-9 sc-215787
25 mg
$360.00
0
(0)
rac-2-Methoxy-3-hexadecanamido-1-propylphosphocholine
163751-35-7 sc-215788
10 mg
$295.00
0
(0)
Rp-8-Br-PET-cGMPs
Rp-8-Br-PET-cGMPs is an inhibitor of cGKI and cGKII
185246-32-6 sc-215820
sc-215820A
1 mg
5 mg
$250.00
$1,040.00
1
(0)
N-Myristoyl-Lys-Arg-Thr-Leu-Arg-OH
N-Myristoyl-Lys-Arg-Thr-Leu-Arg-OH is an inhibitor of histone phosphorylation
125678-68-4 sc-222009
1 mg
$48.00
0
(0)
8-MA-cAMP
CAS: 33823-18-6, MF: C11H14N6O6PNa, MW: 380.23
33823-18-6 sc-257017
5 mg
$200.00
0
(0)
NGIC-I
NGIC-I is a potent, cell-permeable, and selective PKC inhibitor
sc-222073
500 µg
$300.00
0
(0)
(+/-)-alpha-CMBHC
7083-09-2 sc-222431
sc-222431A
1 mg
5 mg
$30.00
$135.00
0
(0)
Y-27632 dihydrochloride
Y-27632 dihydrochloride is a cell permeable inhibitor of ROCK-1 and ROCK-2 which plays an important role in Rho-mediated cell adhesion and smooth muscle
129830-38-2 sc-281642
sc-281642A
1 mg
10 mg
$85.00
$225.00
24
(1)
(+/-) 1,2-Didecanoylglycerol (10:0)
(+/_) 1,2-Didecanoylglycerol (10:0) is a chemical shown to promote protein kinase C in platelets
82950-64-9 sc-287217
5 mg
$26.00
0
(1)
12-Deoxyphorbol 13-phenylacetate 20-acetate
54662-30-5 sc-287296
1 mg
$115.00
0
(0)
TMB-8 dot HCl
TMB-8 • HCl is a PKC inhibitor and a calcium and sodium channel blocker
53464-72-5 sc-3522
sc-3522A
10 mg
50 mg
$41.00
$124.00
10
(1)
(Z)-4-Hydroxytamoxifen
(Z)-4-Hydroxytamoxifen is an active metabolite of the antineoplastic agent Tamoxifen and an anti-estrogen agent
68047-06-3 sc-3542C
sc-3542
sc-3542B
sc-3542A
sc-3542D
sc-3542E
1 mg
5 mg
10 mg
25 mg
50 mg
100 mg
$130.00
$200.00
$290.00
$650.00
$1,220.00
$2,250.00
10
(2)
Zoledronic acid, anhydrous
Zoledronic acid, anhydrous is a protein kinase C activator with apoptotic effects
118072-93-8 sc-364663
sc-364663A
25 mg
100 mg
$80.00
$246.00
0
(0)

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