Trifunctional Crosslinkers

Santa Cruz Biotechnology now offers a broad range of Trifunctional Crosslinkers. Trifunctional Crosslinkers containing biotin are valuable label transfer reagents, typically used to identify protein interactions. Typically one arm of the trifunctional linker consists of a cleavable spacer and a chemoselective reactive group for the initial targeting of a known 'bait' protein. Once attached to the bait protein the photoreactive end can then be activated to bind any nearby, interacting, 'prey' proteins. These captured bait:prey complexes can then undergo various avidin-biotin detection, isolation, or purification techniques. At any point the disulfide bridge can be cleaved by gentle reductive methods to transfer the biotin label to the unknown interacting protein of interest.

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PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
5-[2-Biotinylamidoethyl]-dithiopropionamido]-3,7-diaza-4,6-diketononanoic Acid, Bis-N-sulfosuccinimidyl Ester
5-[2-Biotinylamidoethyl]-dithiopropionamido]-3,7-diaza-4,6-diketononanoic Acid, Bis-N-sulfosuccinimidyl Ester is a cleavable Suflo-NHS and biotin contain
sc-223688
1 mg
$280.00
0
(0)
6-[2-Biotinylamidoethyl]-dithiopropionamido]-4,8-diaza-5,7-diketoundecanoic Acid, Bis-N-sulfosuccinimidyl Ester Disodium Salt
6-[2-Biotinylamidoethyl]-dithiopropionamido]-4,8-diaza-5,7-diketoundecanoic Acid, Bis-N-sulfosuccinimidyl Ester Disodium Salt is a cleavable Suflo-NHS an
1044220-56-5 sc-207084
1 mg
$250.00
0
(0)
[Biotinylamidoethyl]-dithiomethylenemalonic Acid Bis(2-aminoethanoic Acid)
[Biotinylamidoethyl]-dithiomethylenemalonic Acid Bis(2-aminoethanoic Acid) is a cleavable biotin crosslinker
sc-221363
5 mg
$220.00
0
(0)
2-[N2-(N6-t-Boc-6-aminocaproyl)-N6-(6-biotinamidocaproy)-L -lysinylamido]ethyl Methanethiosulfonate
sc-223339
5 mg
$200.00
0
(0)
Trans-3,4-Bis(methylmethanethiosulfonylmethyl)-2,2,5,5-tetramethylpyrrolidin-1-yloxyl Radical
Trans-3,4-Bis(methylmethanethiosulfonylmethyl)-2,2,5,5-tetramethylpyrrolidin-1-yloxyl Radical is a cross-linking, sulfhydryl spin label
229621-30-1 sc-213085
1 mg
$263.00
0
(0)
2-[N2-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-N6-(6 -biotinamidocaproyl)-L-lysinyl]ethyl 2-Carboxyethyl Disulfide
sc-213714
1 mg
$250.00
0
(0)
2-[N2-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-N6-(6-biotinamidocaproyl)-L-lysinyl]ethyl Methanethiosulfonate
2-[N2-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-N6-(6-biotinamidocaproyl)-L-lysinyl]ethyl Methanethiosulfonate is a biotin containing suflhydryl- and photo-re
1356383-18-0 sc-213715
1 mg
$300.00
0
(0)
2-{N2-[N6-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-6 -aminocaproyl]-N6-(6-biotinamidocaproyl)-L -lysinylamido}] Ethyl 2-Carboxyethyl Disulfide
sc-213718
1 mg
$280.00
0
(0)
2-{N2-[N6-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-6- aminocaproyl]-N6-(6-biotinamidocaproyl)-L -lysinylamido}ethyl Methanethiosulfonate
2-{N2-[N6-(4-Azido-2,3,5,6-tetrafluorobenzoyl)-6- aminocaproyl]-N6-(6-biotinamidocaproyl)-L -lysinylamido}ethyl Methanethiosulfonate is a biotin containi
1356841-34-3 sc-213720
sc-213720A
1 mg
10 mg
$250.00
$2,000.00
0
(0)
Biotinylamidoethyl]-dithiomethylenemalonic Acid Bis(3-aminopropionic Acid)
sc-221364
5 mg
$350.00
0
(0)
[Biotinylamidoethyl]-dithiomethylenemalonic Acid Bis(4-aminobutyric Acid)
sc-221365
5 mg
$220.00
0
(0)
2-{N2-[Nalpha-Benzoylbenzoicamido-N6-6-biotinamidocaproyl]lysinylamido}ethyl-2prime-(N-sulfosuccinimidylcarboxy)ethyl Disulfide Sodium Salt
2-{N2-[Nα-Benzoylbenzoicamido-N6-6-biotinamidocaproyl]lysinylamido}ethyl-2′-(N-sulfosuccinimidylcarboxy)ethyl Disulfide Sodium Salt is An amine reactive
sc-229868
1 mg
$210.00
1
(0)
3,4-Bis-(methanethiosulfonylmethyl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxy Radical
229621-21-0 sc-206698
1 mg
$350.00
0
(0)
Benzophenone-4-carboxamidocysteine Methanethiosulfonate
Benzophenone-4-carboxamidocysteine Methanethiosulfonate is A trifunctional conjugate containing a photo reactive benzophenone group and an MTS function f
317821-69-5 sc-217724
10 mg
$280.00
0
(0)
Sulfo-SBED
Sulfo-SBED is an amine reactive trifunctional crosslinking reagent
sc-397353
10 mg
$456.00
0
(0)

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