Date published: 2025-9-14

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1700065O13Rik Inhibitors

1700065O13Rik Inhibitors encompass a range of compounds that indirectly affect the function and activity of the ZNF763 protein through their action on various cellular pathways and processes. This class includes a variety of compounds, each with distinct mechanisms of action, reflecting the multifaceted nature of cellular regulation and the complex interplay of different molecular pathways. Compounds such as 5-Azacytidine and Decitabine, which modulate DNA methylation, can have a profound impact on gene expression patterns. Since ZNF763 is a zinc finger protein, it's likely involved in gene regulation; thus, altering the epigenetic landscape could indirectly influence its regulatory functions. Similarly, HDAC inhibitors like Vorinostat and Trichostatin A can change chromatin structure and thereby potentially impact the gene regulatory roles of ZNF763.

On the other hand, compounds targeting key signaling molecules, such as LY294002 (a PI3K inhibitor) and Rapamycin (an mTOR inhibitor), can affect the broader signaling networks within which ZNF763 might operate. By modulating these pathways, these compounds can indirectly influence the functional context in which ZNF763 operates. Staurosporine, as a broad-spectrum kinase inhibitor, can impact a range of signaling pathways, potentially affecting the activity of proteins that interact with or regulate ZNF763. Other compounds like Bortezomib, Thalidomide, and Olaparib target specific aspects of cellular function such as proteasome activity, transcription factor degradation, and DNA repair mechanisms, respectively. These actions can create a cellular environment that affects the stability, interactions, or regulatory roles of ZNF763. Nutlin-3 and Palbociclib, by modulating p53 activity and cell cycle progression, respectively, can also indirectly influence the functional dynamics of ZNF763.

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