简介 HOVERcruz™a unique system for rapid identification of GrpEL Antibodies. Hover over the icon next to the product names in the table to see representative data for that product.
GrpEL CRISPR Knockout, HDR and Nickase Knockout Plasmids include:
GrpEL 特异 siRNA, shRNA 质粒和 shRNA 慢病毒颗粒基因沉默子产品包括：
GrpEL2 (GrpE protein homolog 2) is a 225 amino acid mitochondrial matrix protein and component of the PAM complex. Consisting of Tim44, Tim14, HSP 70, Magmas, GrpEL1 and GrpEL2, the PAM complex plays an essential role in the ATP-dependent translocation of transit peptide-containing proteins to the mitochondrial matrix from the inner membrane. GrpEL2 regulates the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins and stimulates its ATPase activity. The gene encoding GrpEL2 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.