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EMSY (A-15) 抗体: sc-34995

 |  说明书
  • goat polyclonal IgG, 200 µg/ml
  • epitope mapping near the N-terminus of EMSY of human origin
  • recommended for detection of EMSY isoforms 1 and 2 of mouse and human origin by WB, IP, IF and ELISA; also reactive with additional species, including canine, bovine, porcine and avian
  • blocking peptide, sc-34995 P
 
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WB   IP   IF   siRNA  
 
种属 基因名称 基因ID 染色质位置 亚型(mRNA)即位号码 蛋白质即位号码 OMIM™ 号码
人类 C11orf30 56946 11q13.5 NM_020193 Q7Z589
608573
小鼠 2210018M11Rik 233545 7 E2 Q8BMB0
N/A
 
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产品名称产品编号规格价格数量添加我的最爱
EMSY (A-15) sc-34995 200 µg/ml $279
EMSY (A-15) P sc-34995 P
(peptide)
100 µg/0.5 ml $61
 siRNA 基因沉默子 (点击产品名称查看详细信息‭ ‬)
产品名称产品编号规格价格数量添加我的最爱
EMSY siRNA (h) sc-45565 10 µM $258
EMSY siRNA (m) sc-45566 10 µM $258
EMSY siRNA (h)-PR sc-45565-PR 10 µM $23
EMSY siRNA (m)-PR sc-45566-PR 10 µM $23
 shRNA 质粒 (点击产品名称查看详细信息‭ ‬)
产品名称产品编号规格价格数量添加我的最爱
EMSY shRNA Plasmid (h) sc-45565-SH 20 µg $520
EMSY shRNA Plasmid (m) sc-45566-SH 20 µg $520
 shRNA 慢病毒颗粒 (点击产品名称查看详细信息‭ ‬)
产品名称产品编号规格价格数量添加我的最爱
EMSY siRNA shRNA (h) Lentiviral Particles sc-45565-V 200 µl $625
EMSY siRNA shRNA (m) Lentiviral Particles sc-45566-V 200 µl $625
 WB 阳性对照细胞裂解液 (点击产品名称查看详细信息‭ ‬)
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HeLa Whole Cell Lysate sc-2200 500 µg/200 µl $104

EMSY Background Information
EMSY interacts with BRCA2 and plays a role in chromatin remodeling. This interaction has been confirmed in HeLa cells. Overexpression of EMSY strongly correlates with amplification in sporadic breast cancer and higher grade ovarian cancer. The EMSY gene is amplified in 18% of breast cancer cell lines. EMSY amplification is highly correlated with DNA amplification in both cell lines and primary tumors. This amplification is a general sign of poor prognosis and shortened disease-free survival time. EMSY from a wide variety of species has a conserved 80 amino acid sequence at the N-terminus. In irradiated MEFs (mouse embryonic fibroblasts), EMSY was found to migrate to damaged DNA.

EMSY (A-15)
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EMSY (A-15): sc-34995. Western blot analysis of EMSY expression in HeLa whole cell lysate.
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