Nap1 Background Information Cell cycle progression is controlled at a point late in G1, designated Start. Passage through Start requires the activity of the cyclin-dependent protein kinase Cdc28 (1,2). Transition from G1 to S phase requires the association of Cdc28 with members of the the G1 cyclin family, including Cln1, Cln2 and Cln3 (also designated Daf1 or Whi1) (3). The G2 to M phase transition requires the M phase cyclins, Clb1 (also referred to as SCB1) and Clb2, as well as the G2 cyclins, Clb3 and Clb4 (4,5). CLB2 is bound by Nap1, a protein required for Clb2 to function in specific mitotic events (6). Nap1 is also required for Clb2 to induce the transition from polar to isotropic bud growth (7,8).
Nap1 (D-2)
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Nap1 (D-2): sc-25342. Western blot analysis of yeast recombinant Nap1 fusion protein.
