Tenascin-C Antibody (E-9): sc-25328
- Tenascin-C Antibody (E-9) is a mouse monoclonal IgG1 κ Tenascin-C antibody, cited in 15 publications, provided at 200 µg/ml
- raised against amino acids 1601-1900 of Tenascin-C of human origin
- Tenascin-C Antibody (E-9) is recommended for detection of Tenascin-C of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-Tenascin-C Antibody (E-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Tenascin-C Antibody (E-9) for WB and IHC(P) applications. These reagents are now offered in bundles with Tenascin-C Antibody (E-9) (see ordering information below).
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Tenascin-C Antibody (E-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects Tenascin-C protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-Tenascin-C antibody (E-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Tenascin-C, a member of the tenascin family of extracellular matrix proteins, plays a crucial role in cellular adhesion and migration, which are vital processes during development and tissue repair. Tenascin-C is primarily located in the extracellular matrix, where Tenascin-C influences cell behavior by interacting with integrins and other cell surface receptors, thereby modulating cellular responses to environmental cues. Tenascin-C expression is particularly important in tissues undergoing remodeling, such as during wound healing and tumor progression, as Tenascin-C helps regulate the balance between cell adhesion and migration. Tenascin-C′s structure, characterized by multiple EGF-like and fibronectin type-III domains, allows for formation of large hexameric complexes that create a scaffold for cell attachment and migration, further emphasizing Tenascin-C′s significance in developmental processes and tissue homeostasis.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Tenascin-C Antibody (E-9) References:
- Tenascin-C in the matrisome of neural stem and progenitor cells. | Faissner, A., et al. 2017. Mol Cell Neurosci. 81: 22-31. PMID: 27836730
- Tenascin-C in Heart Diseases-The Role of Inflammation. | Imanaka-Yoshida, K. 2021. Int J Mol Sci. 22: PMID: 34072423
- Tenascin-C induction exacerbates post-stroke brain damage. | Chelluboina, B., et al. 2022. J Cereb Blood Flow Metab. 42: 253-263. PMID: 34689646
- Tenascin-C as a potential marker for immunohistopathology of doxorubicin-induced cardiomyopathy. | Nishikawa, T., et al. 2023. Eur Heart J Open. 3: oead104. PMID: 37908440
- Tenascin-C expressing touch dome keratinocytes exhibit characteristics of all epidermal lineages. | Nguyen, MB., et al. 2024. Sci Adv. 10: eadi5791. PMID: 38241368
- Tenascin-C modulates alveolarization in bronchopulmonary dysplasia. | Liu, W., et al. 2024. Inflamm Regen. 44: 16. PMID: 38539268
- The perplexing multifunctionality of janusin, a tenascin-related molecule. | Schachner, M., et al. 1994. Perspect Dev Neurobiol. 2: 33-41. PMID: 7530142
- Tenascins, a growing family of extracellular matrix proteins. | Chiquet-Ehrismann, R. 1995. Experientia. 51: 853-62. PMID: 7556567
- Astrocytes and neurons regulate the expression of the neural recognition molecule janusin by cultured oligodendrocytes. | Jung, M., et al. 1993. Glia. 9: 163-75. PMID: 8294147
- Characterization of the bovine tenascin-X. | Elefteriou, F., et al. 1997. J Biol Chem. 272: 22866-74. PMID: 9278449
- The tenascin gene family in axon growth and guidance. | Faissner, A. 1997. Cell Tissue Res. 290: 331-41. PMID: 9321695
- Interaction of voltage-gated sodium channels with the extracellular matrix molecules tenascin-C and tenascin-R. | Srinivasan, J., et al. 1998. Proc Natl Acad Sci U S A. 95: 15753-7. PMID: 9861042
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Tenascin-C Antibody (E-9) | sc-25328 | 200 µg/ml | $322.00 | |||
Tenascin-C Antibody (E-9): m-IgG Fc BP-HRP Bundle | sc-526650 | 200 µg Ab; 10 µg BP | $361.00 | |||
Tenascin-C Antibody (E-9): m-IgG1 BP-HRP Bundle | sc-532023 | 200 µg Ab; 20 µg BP | $361.00 | |||
Tenascin-C Antibody (E-9) AC | sc-25328 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Tenascin-C Antibody (E-9) HRP | sc-25328 HRP | 200 µg/ml | $322.00 | |||
Tenascin-C Antibody (E-9) FITC | sc-25328 FITC | 200 µg/ml | $336.00 | |||
Tenascin-C Antibody (E-9) PE | sc-25328 PE | 200 µg/ml | $349.00 | |||
Tenascin-C Antibody (E-9) Alexa Fluor® 488 | sc-25328 AF488 | 200 µg/ml | $364.00 | |||
Tenascin-C Antibody (E-9) Alexa Fluor® 546 | sc-25328 AF546 | 200 µg/ml | $364.00 | |||
Tenascin-C Antibody (E-9) Alexa Fluor® 594 | sc-25328 AF594 | 200 µg/ml | $364.00 | |||
Tenascin-C Antibody (E-9) Alexa Fluor® 647 | sc-25328 AF647 | 200 µg/ml | $364.00 | |||
Tenascin-C Antibody (E-9) Alexa Fluor® 680 | sc-25328 AF680 | 200 µg/ml | $364.00 | |||
Tenascin-C Antibody (E-9) Alexa Fluor® 790 | sc-25328 AF790 | 200 µg/ml | $364.00 |