Mig-2 Background Information Mig-2 recruits migfilin to cell-matrix adhesions, while the interaction with filamin mediates the association of migfilin with actin filaments. Together, Mig-2, migfilin and filamin define a connection between cell matrix adhesions and the actin cytoskeleton and participate in the orchestration of actin assembly and cell shape modulation. Mig-2 expression is transcriptionally elevated in leiomyomas and could be involved in its hormone-mediated growth of leiomyomas of the uterus. Expression of Mig-2 is ubiquitous, and it is found in numerous tumor tissues.
Mig-2 (NQ-A16)
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Mig-2 (NQ-A16): sc-134387. Western blot analysis of Mig-2 expression in human Mig-2 transfected (A) and non-transfected (B) 293T whole cell lysates.
