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Tom AntibodiesSanta Cruz Biotechnology, Inc. offers a broad range of Tom antibodies. Select Tom antibodies from several monoclonal and/or polyclonal Tom antibodies listed below. View detailed Tom antibody specifications by linking to the specific product blocks. Select appropriate Tom antibodies for your research by isotype, epitope, applications and species reactivity. Tom gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available. Introducing HOVERcruz™,a unique system for rapid identification of Tom Antibodies. Hover over product names in the table to see representative data for each product.Live chat is now available! (click here)Our live chat system is available to answer your product and ordering questions.Also see additional Tom Antibodies including, Tom1, Tom1L-1, Tom1L-2, Tom6, Tom7, Tom20, Tom22... See More, Tom34, Tom40, Tom70
Tom siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:
The mitochondrial protein translocase (MPT) shuttles preproteins into the mitochondria via recognition of an amino-terminal signal sequence (presequence) or an internal targeting domain within the preprotein. MPT contains several components that form three translocons, one in the outer membrane (Tom40/70) and two in the inner membrane (Tim17/23 and Tim22/54). The integral membrane proteins of the MPT include Tom70, Tom37, Tom22 and Tom20. MPT-dependent transport delivers the substrate protein to an outer membrane channel consisting of 5 hydrophobic proteins, Tom40, Tom38, Tom7, Tom6 and Tom5. Tom1 is thought to be involved in intracellular trafficking and may be associated with the translocation of ubiquitinated proteins to early endosomes for degradation. Tom1L-1 (target of myb1 (chicken)-like 1) interacts with Fyn, GRB2, PI 3-kinase p85å and various signaling proteins when phosphorylated. GAT domain of Tom1L1 binds ubiquitin, suggesting participation in the sorting of ubiquitinated proteins into MVBs. Tom34 functions as a chaperone-like protein that binds the mature portion of unfolded proteins and guides their import into mitochondria. In addition, Tom34 is thought to have weak ATPase activity and may interact with other organelles within the cell. |
