TFIIH Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of TFIIH antibodies. Select TFIIH antibodies from several monoclonal and/or polyclonal TFIIH antibodies listed below. View detailed TFIIH antibody specifications by linking to the specific product blocks. Select appropriate TFIIH antibodies for your research by isotype, epitope, applications and species reactivity. TFIIH gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available.

Introducing HOVERcruz™,

Live chat is now available! (click here)

Also see additional TFIIH Antibodies including, TFIIH p8, TFIIH p34, TFIIH p44, TFIIH p44L, TFIIH p52, TFIIH p62, TFIIH p80... See More, TFIIH p89

Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of 5 subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.