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SorCS Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of SorCS antibodies. Select SorCS antibodies from several monoclonal and/or polyclonal SorCS antibodies listed below. View detailed SorCS antibody specifications by linking to the specific product blocks. Select appropriate SorCS antibodies for your research by isotype, epitope, applications and species reactivity. SorCS gene silencer products in siRNA, shRNA Plasmid, shRNA Lentiviral Particle and CRISPR/Cas9 Knockout Plasmid formats are also available as well as CRISPR/dCas9 Activation Plasmids for gene activation.

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a unique system for rapid identification of SorCS Antibodies. Hover over product names in the table to see representative data for each product.

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Also see additional SorCS Antibodies including, SorCS1, SorCS2, SorCS3

PRODUCT NAMECAT. #ISOTYPEEPITOPEAPPLICATIONSSPECIESCITATIONSRATING
SorCS1 (E-8)sc-365605mouse IgG134-153 (h)WB, IP, IF, ELISAhuman
SorCS1 (H-120)sc-67092rabbit IgG34-153 (h)WB, IP, IF, ELISAhuman
SorCS1 (M-15)sc-32341goat IgGC-terminal (m)WB, IF, ELISAm, r, h, e, c, b, p, a
SorCS1 (M-120)sc-67093rabbit IgG34-153 (m)WB, IP, IF, ELISAm, r
SorCS1 (D-20)sc-32340goat IgGinternal (m)WB, IF, ELISAm, r, h, e, c, b, p, a
SorCS2 (A-10)sc-398412mouse IgG2a755-1012 (h)WB, IP, IF, ELISAhumanNEW
SorCS2 (D-12)sc-104658goat IgGInternal (h)WB, IF, ELISAm, r, h, e, c
SorCS2 (H-258)sc-368356rabbit IgG755-1012 (h)WB, IP, IF, ELISAm, r, hNEW
SorCS3 (C-19)sc-324334goat IgGC-terminal (h)WB, IF, ELISAm, r, h
SorCS3 (N-17)sc-324332goat IgGN-terminal (h)WB, IF, ELISAhuman
SorCS2 (V-14)sc-104660goat IgGInternal (h)WB, IF, ELISAm, r, hNEW

SorCS CRISPR Knockout and HDR Plasmids include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSCITATIONSRATING
SorCS1 CRISPR/Cas9 KO Plasmid (h)sc-406146humanGene KnockoutNEWNot Yet Rated
SorCS1 HDR Plasmid (h)sc-406146-HDRhumanHomology Directed RepairNEWNot Yet Rated
SorCS2 CRISPR/Cas9 KO Plasmid (h)sc-407821humanGene KnockoutNEWNot Yet Rated
SorCS2 HDR Plasmid (h)sc-407821-HDRhumanHomology Directed RepairNEWNot Yet Rated
SorCS3 CRISPR/Cas9 KO Plasmid (h)sc-411644humanGene KnockoutNEWNot Yet Rated
SorCS3 HDR Plasmid (h)sc-411644-HDRhumanHomology Directed RepairNEWNot Yet Rated
SorCS1 CRISPR/Cas9 KO Plasmid (m)sc-425469mouseGene KnockoutNEWNot Yet Rated
SorCS1 HDR Plasmid (m)sc-425469-HDRmouseHomology Directed RepairNEWNot Yet Rated
SorCS3 CRISPR/Cas9 KO Plasmid (m)sc-426141mouseGene KnockoutNEWNot Yet Rated
SorCS3 HDR Plasmid (m)sc-426141-HDRmouseHomology Directed RepairNEWNot Yet Rated
SorCS2 CRISPR/Cas9 KO Plasmid (m)sc-429879mouseGene KnockoutNEWNot Yet Rated
SorCS2 HDR Plasmid (m)sc-429879-HDRmouseHomology Directed RepairNEWNot Yet Rated

SorCS CRISPR Activation Plasmids include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSCITATIONSRATING
SorCS1 CRISPR Activation Plasmid (h)sc-406146-ACThumanGene ActivationNEWNot Yet Rated
SorCS2 CRISPR Activation Plasmid (h)sc-407821-ACThumanGene ActivationNEWNot Yet Rated
SorCS3 CRISPR Activation Plasmid (h)sc-411644-ACThumanGene ActivationNEWNot Yet Rated
SorCS1 CRISPR Activation Plasmid (m)sc-425469-ACTmouseGene ActivationNEWNot Yet Rated
SorCS3 CRISPR Activation Plasmid (m)sc-426141-ACTmouseGene ActivationNEWNot Yet Rated
SorCS2 CRISPR Activation Plasmid (m)sc-429879-ACTmouseGene ActivationNEWNot Yet Rated

SorCS siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

PRODUCT NAMECAT. #SPECIESAPPLICATIONSCITATIONSRATING
SorCS1 siRNA (h)sc-44745humanGene SilencingNot Yet Rated
SorCS1 shRNA Plasmid (h)sc-44745-SHhumanGene SilencingNot Yet Rated
SorCS1 shRNA (h) Lentiviral Particlessc-44745-VhumanGene SilencingNot Yet Rated
SorCS1 siRNA (m)sc-44746mouseGene Silencing
SorCS1 shRNA Plasmid (m)sc-44746-SHmouseGene Silencing
SorCS1 shRNA (m) Lentiviral Particlessc-44746-VmouseGene Silencing
SorCS2 siRNA (h)sc-88953humanGene SilencingNot Yet Rated
SorCS2 shRNA Plasmid (h)sc-88953-SHhumanGene SilencingNot Yet Rated
SorCS2 shRNA (h) Lentiviral Particlessc-88953-VhumanGene SilencingNot Yet Rated
SorCS2 siRNA (m)sc-106557mouseGene SilencingNot Yet Rated
SorCS2 shRNA Plasmid (m)sc-106557-SHmouseGene SilencingNot Yet Rated
SorCS2 shRNA (m) Lentiviral Particlessc-106557-VmouseGene SilencingNot Yet Rated
SorCS3 siRNA (h)sc-106558humanGene SilencingNot Yet Rated
SorCS3 shRNA Plasmid (h)sc-106558-SHhumanGene SilencingNot Yet Rated
SorCS3 shRNA (h) Lentiviral Particlessc-106558-VhumanGene SilencingNot Yet Rated
SorCS3 siRNA (m)sc-153685mouseGene SilencingNot Yet Rated
SorCS3 shRNA Plasmid (m)sc-153685-SHmouseGene SilencingNot Yet Rated
SorCS3 shRNA (m) Lentiviral Particlessc-153685-VmouseGene SilencingNot Yet Rated

There are three sorCS genes that have diverse, partially overlapping functions in the central nervous system. In the developing and mature central nervous system, the homologous SorCS1 and SorCS2 genes and the SorCS3 gene are expressed in a combinatorial, non-overlapping pattern. SorCS proteins show homology to the mosaic receptor SorLA and the neurotensin receptor sortilin, based on a common VPS10 domain, which is the hallmark of the SorCS receptor family. SorCS1 is a type 1 receptor containing a VPS10P domain and a leucine-rich domain. Alternative splicing of human SorCS1 results in four isoforms with different cytoplasmic tails and differential expression in tissues. Human SorCS1 is detected in fetal and infant brain and in fetal retina. Alternative splicing of murine SorCS1 also results in four isoforms. Murine isoform 1 is highly expressed in brain and at lower levels in heart, liver and kidney. It is detected in newborn mouse brain and in adult olfactory bulb and cerebral cortex. Murine isoform 2 is highly expressed in liver and at lower levels in heart, brain, kidney and testis.