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SMA CRISPR/Cas9 Knockout Plasmids and si/shRNA Gene Silencers

Santa Cruz Biotechnology, Inc. offers a broad range of gene silencers in the form of siRNAs, shRNA Plasmids and shRNA Lentiviral Particles as well as CRISPR/Cas9 Knockout plasmids. SMA gene silencers are available as SMA siRNA, SMA shRNA Plasmid, SMA shRNA Lentiviral Particles and SMA CRISPR/Cas9 Knockout plasmids. Gene silencers are useful for gene studies in combination with antibodies used for protein detection.

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PRODUCT NAMECAT. #ISOTYPEEPITOPEAPPLICATIONSSPECIESCITATIONSRATING
SMA5 (D-18)sc-324317goat IgGC-terminal (h)WB, IF, ELISAhuman1
SMA5 (N-17)sc-324316goat IgGN-terminal (h)WB, IF, ELISAhuman

SMA siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

siRNAsshRNA PlasmidsshRNA Lentiviral ParticlesCITATIONSRANKING
SMA5 siRNA (h): sc-92040SMA5 shRNA Plasmid (h):
sc-92040-SH
SMA5 shRNA (h)
Lentiviral Particles: sc-92040-V
Not Yet Rated

SMA5 is a 140 amino acid protein that is encoded by a gene mapping to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.