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SLA/LP AntibodiesSanta Cruz Biotechnology, Inc. offers a broad range of SLA/LP antibodies. Select SLA/LP antibodies from several monoclonal and/or polyclonal SLA/LP antibodies listed below. View detailed SLA/LP antibody specifications by linking to the specific product blocks. Select appropriate SLA/LP antibodies for your research by isotype, epitope, applications and species reactivity. SLA/LP gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available. Introducing HOVERcruz™,a unique system for rapid identification of SLA/LP Antibodies. Hover over product names in the table to see representative data for each product.Live chat is now available! (click here)Our live chat system is available to answer your product and ordering questions.
SLA/LP siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:
The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases. Aminoacyl-tRNA synthetases function to catalyze the aminoacylation of tRNAs by their corresponding amino acids, thus linking amino acids with tRNA-contained nucleotide triplets.SLA/LP (Soluble liver antigen/Liver-pancreas antigen), also known as SEPSECS (Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase) or SLA-p35, is a 501 amino acid cytoplasmic protein that belongs to a diverse family of pyridoxal phosphate-dependent enzymes. Expressed predominantly in liver, lung, kidney and pancreas, SLA/LP plays a role in aminoacyl-tRNA synthesis and, more specifically, selenoprotein biosynthesis. Using PLP as a cofactor, SLA/LP specifically converts O-phosphoseryl-tRNA(Sec) to Sec-tRNA(Sec) by exchanging the phosphate group for a selenol moiety. Due to alternative splicing events, two SLA/LP isoforms exist. |
