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ROR1 AntibodiesSanta Cruz Biotechnology, Inc. offers a broad range of ROR1 antibodies. Select ROR1 antibodies from several monoclonal and/or polyclonal ROR1 antibodies listed below. View detailed ROR1 antibody specifications by linking to the specific product blocks. Select appropriate ROR1 antibodies for your research by isotype, epitope, applications and species reactivity. ROR1 gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available. Introducing HOVERcruz™,a unique system for rapid identification of ROR1 Antibodies. Hover over product names in the table to see representative data for each product.Live chat is now available! (click here)Our live chat system is available to answer your product and ordering questions.
ROR1 siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:
The ROR-family receptor tyrosine kinases consist of two structurally related proteins, ROR1 and ROR2. These proteins are characterized by having intracellular tyrosine kinase domains, which are highly related to Trk-family kinases, extracellular Frizzled-like cysteine-rich domains (CRDs) and Kringle domains. The ROR family members are highly conserved among species, such as C. elegans, Drosophila, Xenopus and mammals. ROR1 and ROR2 are both involved in organogenesis with particular emphasis in neuronal differentiation. Increased expression of ROR1 in acute lymphoblastic leukemias (ALLs) as well as chronic lymphocytic leukemias (CLLs) implicate this protein as a potential tool for targeted immunotherapy in these diseases. ROR2 is involved in the Wnt-signalling pathway, and mutations in ROR2 lead to Brachydactyly type B and Robinow Syndrome. |
