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RNGTT AntibodiesSanta Cruz Biotechnology, Inc. offers a broad range of RNGTT antibodies. Select RNGTT antibodies from several monoclonal and/or polyclonal RNGTT antibodies listed below. View detailed RNGTT antibody specifications by linking to the specific product blocks. Select appropriate RNGTT antibodies for your research by isotype, epitope, applications and species reactivity. RNGTT gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available. Introducing HOVERcruz™,a unique system for rapid identification of RNGTT Antibodies. Hover over product names in the table to see representative data for each product.Live chat is now available! (click here)Our live chat system is available to answer your product and ordering questions.
RNGTT siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:
RNGTT (RNA guanylyltransferase and 5'-phosphatase), also known as HCE, HCE1, hCAP or CAP1A, is a 597 amino acid protein that localizes to the nucleus and exists as four alternatively spliced isoforms. Expressed in kidney, lung, heart, brain, liver, testis, skin and muscle, RNGTT acts as a bifunctional mRNA-capping enzyme that exhibits RNA 5'-triphosphatase activity at its N-terminus and mRNA guanylyltransferase activity at its C-terminus. Via its catalytic activity, RNGTT facilitates the first two steps of mRNA cap formation, naming the removal of a γ-phosphate from the end of nascent mRNA and the subsequent transfer of the phospho residue to the 5’-diphosphate terminus. The gene encoding RNGTT maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6% of the human genome. |
