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RFX AntibodiesSanta Cruz Biotechnology, Inc. offers a broad range of RFX antibodies. Select RFX antibodies from several monoclonal and/or polyclonal RFX antibodies listed below. View detailed RFX antibody specifications by linking to the specific product blocks. Select appropriate RFX antibodies for your research by isotype, epitope, applications and species reactivity. RFX gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available. Introducing HOVERcruz™,a unique system for rapid identification of RFX Antibodies. Hover over product names in the table to see representative data for each product.Live chat is now available! (click here)Our live chat system is available to answer your product and ordering questions.Also see additional RFX Antibodies including, RFX-B, RFX1, RFX2, RFX3, RFX4, RFX5, RFX6... See More, RFX7, RFX8
RFX siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:
The EP-like element is bound by a ubiquitous nuclear protein complex that consists of homo- and heterodimers involving the RFX1, RFX2, RFX3, RFX4, RFX5, RFX6 AND RFX7 proteins. The RFX proteins represent an essential class II transcription factor family that share several conserved regions, including a centrally located DNA-binding domain (DBD) and a C-terminal D region that facilitates dimerization. RFX complexes can activate the enhancer elements of several HBV genes and also promote the induction of MHC class II genes in response to interferon-g stimulation. RFX5, RFX-B/Ank and RFXAP comprise the RFX trimer, which binds to X and S boxes in MHC class II promoters. Even though RFXAP lacks a DNA-binding domain, RFXAP and RFX-B/Ank are essential to the RFX DNA-binding function. The RFXAP interacts specifically with RFX5. Loss of RFXAP function is linked to MHC class II deficiency disease class D. |
