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PTCHD AntibodiesSanta Cruz Biotechnology, Inc. offers a broad range of PTCHD antibodies. Select PTCHD antibodies from several monoclonal and/or polyclonal PTCHD antibodies listed below. View detailed PTCHD antibody specifications by linking to the specific product blocks. Select appropriate PTCHD antibodies for your research by isotype, epitope, applications and species reactivity. PTCHD gene silencer products in siRNA, shRNA Plasmid and shRNA Lentiviral Particle formats are also available. Introducing HOVERcruz™,a unique system for rapid identification of PTCHD Antibodies. Hover over product names in the table to see representative data for each product.Live chat is now available! (click here)Our live chat system is available to answer your product and ordering questions.Also see additional PTCHD Antibodies including, PTCHD1, PTCHD2, PTCHD3
PTCHD siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:
PTCHD3 (patched domain-containing protein 3), also known as PTR (patched-related protein), is a 767 amino acid multi-pass membrane protein that localizes to the midpiece of the sperm tail, where it is Implicated in sperm function and development. A member of the patched family, PTCHD3 contains one SSD (sterol-sensing) domain and is encoded by a gene that maps to human chromosome 10p12.1. PTCHD2 (patched domain containing 2), also known as protein dispatched homolog 3 or DISP3, is a 1,392 amino acid multi-pass membrane protein that contains one SSD (sterol-sensing) domain and belongs to the patched family. Expressed in retina, brain and testis, PTCHD2 localizes to endoplasmic reticulum and colocalizes with cholesterol. PTCHD2 overexpression leads to increased cholesterol levels, suggesting that PTCHD2 may play a role in cholesterol homeostasis. PTCHD2 is further hypothesized to act as a link between thyroid hormone and cholesterol metabolism. Existing as two alternatively spliced isoforms, PTCHD2 is thought to assist in the release of lipid-anchored secreted proteins and is encoded by a gene that maps to human chromosome 1p36.22. |
