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PPT Antibodies

Santa Cruz Biotechnology, Inc. offers a broad range of PPT antibodies. Select PPT antibodies from several monoclonal and/or polyclonal PPT antibodies listed below. View detailed PPT antibody specifications by linking to the specific product blocks. Select appropriate PPT antibodies for your research by isotype, epitope, applications and species reactivity. PPT gene silencer products in siRNA, shRNA Plasmid, shRNA Lentiviral Particle and CRISPR/Cas9 Knockout Plasmid formats are also available.

Introducing HOVERcruz™,

a unique system for rapid identification of PPT Antibodies. Hover over product names in the table to see representative data for each product.

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PRODUCT NAMECAT. #ISOTYPEEPITOPEAPPLICATIONSSPECIESCITATIONSRATING
PPT2 (D-14)sc-169020goat IgGInternal (h)WB, IF, ELISAm, r, h, e, c, b, p
PPT2 (C-18)sc-130238rabbit IgGN/AWB, IP, ELISAm, h
PPT2 (FL-302)sc-292953rabbit IgGFL (h)WB, IP, IF, ELISAm, r, hNEW

PPT CRISPR/Cas9 Knockout Plasmids include:

PRODUCT NAMECAT. #APPLICATIONSSPECIESCITATIONS
PPT2 CRISPR/Cas9 KO Plasmid (h)sc-407546gene knockouthumanNEW
PPT2 CRISPR/Cas9 KO Plasmid (m)sc-424858gene knockoutmouseNEW

PPT siRNA, shRNA Plasmid and shRNA Lentiviral Particles gene silencers include:

siRNAsshRNA PlasmidsshRNA Lentiviral ParticlesCITATIONSRANKING
PPT2 siRNA (h): sc-95460PPT2 shRNA Plasmid (h):
sc-95460-SH
PPT2 shRNA (h)
Lentiviral Particles: sc-95460-V
Not Yet Rated
PPT2 siRNA (m): sc-152428PPT2 shRNA Plasmid (m):
sc-152428-SH
PPT2 shRNA (m)
Lentiviral Particles: sc-152428-V
Not Yet Rated

PPT2 (palmitoyl-protein thioesterase 2), also known as G14, is a 302 amino acid glycosylated protein that localizes to the lysosome and belongs to the palmitoyl-protein thioesterase family. Expressed throughout the body with highest levels in skeletal muscle, PPT2 functions to remove thioester-linked fatty acyl groups from a variety of substrates, including S-palmitoyl-CoA, thereby playing an important role in lipid metabolism. PPT2 operates at an optimal pH of 7 and exhibits the highest activity for the acyl groups on myristic and palmitic acids, with lower levels of activity toward other short- and long-chain acyl substrates. PPT2 exists as two isoforms, one of which is expressed at low levels and is catalytically inactive.